Micah M Murray,David J Lewkowicz,Amir Amedi et al.
Micah M Murray et al.
Multisensory processes are fundamental in scaffolding perception, cognition, learning, and behavior. How and when stimuli from different sensory modalities are integrated rather than treated as separate entities is poorly understood. We rev...
Jonathan E Peelle,Arthur Wingfield
Jonathan E Peelle
During hearing, acoustic signals travel up the ascending auditory pathway from the cochlea to auditory cortex; efferent connections provide descending feedback. In human listeners, although auditory and cognitive processing have sometimes b...
Olga I Kahn,Peter W Baas
Olga I Kahn
Navigation of the growth cone at the tip of the developing axon is crucial for the proper wiring of the nervous system. Mechanisms of actin-dependent growth cone steering, via signaling cascades, are well documented. Microtubules are also i...
GABAergic Function as a Limiting Factor for Prefrontal Maturation during Adolescence [0.03%]
青春期前额叶成熟过程中GABA能功能的限制因素
Adriana Caballero,Kuei Y Tseng
Adriana Caballero
Adolescence is a vulnerable period for the onset of mental illnesses including schizophrenia and affective disorders, yet the neurodevelopmental processes underlying this vulnerability remain poorly understood. The prefrontal cortex (PFC) a...
Prefrontal Cortical Opioids and Dysregulated Motivation: A Network Hypothesis [0.03%]
前额皮层阿片类物质与动机失调:网络假说
Brian A Baldo
Brian A Baldo
Loss of inhibitory control over appetitively motivated behavior occurs in multiple psychiatric disorders, including drug abuse, behavioral addictions, and eating disorders with binge features. In this opinion article, novel actions of μ-op...
Patrick J Mulholland,L Judson Chandler,Peter W Kalivas
Patrick J Mulholland
Despite the enormous societal burden of alcohol and drug addiction and abundant research describing drug-induced maladaptive synaptic plasticity, there are few effective strategies for treating substance use disorders. Recent awareness that...
Taking a Toll on Self-Renewal: TLR-Mediated Innate Immune Signaling in Stem Cells [0.03%]
toll-like receptor介导的干细胞先天免疫信号转导
Alvaro G Alvarado,Justin D Lathia
Alvaro G Alvarado
Innate immunity has evolved as the front-line cellular defense mechanism to acutely sense and decisively respond to microenvironmental alterations. The Toll-like receptor (TLR) family activates signaling pathways in response to stimuli and ...
Metastability and Coherence: Extending the Communication through Coherence Hypothesis Using a Whole-Brain Computational Perspective [0.03%]
关于相干性的元稳定性和连贯性:从全脑计算视角扩展连贯性交流假设
Gustavo Deco,Morten Kringelbach
Gustavo Deco
Published Erratum
Trends in neurosciences. 2016 Jun;39(6):432. DOI:10.1016/j.tins.2016.04.006 2016
Douglas Storace,Masoud Sepehri Rad,BokEum Kang et al.
Douglas Storace et al.
Genetically encoded optical sensors of cell activity are powerful tools that can be targeted to specific cell types. This is especially important in neuroscience because individual brain regions can include a multitude of different cell typ...
Blake A Pellman,Jeansok J Kim
Blake A Pellman
Foraging-associated predation risk is a natural problem all prey must face. Fear evolved due to its protective functions, guiding and shaping behaviors that help animals adapt to various ecological challenges. Despite the breadth of risky s...