Demystifying cognitive flexibility: Implications for clinical and developmental neuroscience [0.03%]
解开认知灵活性之谜：对临床和发育神经科学的意义
Dina R Dajani,Lucina Q Uddin
Dina R Dajani
Cognitive flexibility, the readiness with which one can selectively switch between mental processes to generate appropriate behavioral responses, develops in a protracted manner and is compromised in several prevalent neurodevelopmental dis...
Camille Allene,Joana Lourenço,Alberto Bacci
Camille Allene
In the neocortex, different types of excitatory and inhibitory neurons connect to one another following a detailed blueprint, defining functionally-distinct subnetworks, whose activity and modulation underlie complex cognitive functions. We...
Do stars govern our actions? Astrocyte involvement in rodent behavior [0.03%]
星真的影响我们的行为吗？小胶质细胞参与啮齿动物的行为
João Filipe Oliveira,Vanessa Morais Sardinha,Sónia Guerra-Gomes et al.
João Filipe Oliveira et al.
Astrocytes have emerged as important partners of neurons in information processing. Important progress has been made in the past two decades in understanding the role of astrocytes in the generation of neuron-astrocyte network outputs resul...
Dragos Inta,Heather A Cameron,Peter Gass
Dragos Inta
Most neurons are generated during development and are not replaced during adulthood, even if they are lost to injury or disease. However, it is firmly established that new neurons are generated in the dentate gyrus of the hippocampus of alm...
Laura A Atherton,David Dupret,Jack R Mellor
Laura A Atherton
The consolidation of memories for places and events is thought to rely, at the network level, on the replay of spatially tuned neuronal firing patterns representing discrete places and spatial trajectories. This occurs in the hippocampal-en...
África Flores,Rocío Saravia,Rafael Maldonado et al.
África Flores et al.
An understanding of the neurobiological mechanisms involved in the regulation of fear is essential for the development of new treatments for anxiety disorders, such as phobias, panic, and post-traumatic stress disorders (PTSD). Orexins, als...
Michael A Bemben,Seth L Shipman,Roger A Nicoll et al.
Michael A Bemben et al.
A fundamental physical interaction exists across the synapse. It is mediated by synaptic adhesion molecules, and is among the earliest and most indispensable of molecular events occurring during synaptogenesis. The regulation of adhesion mo...
Origins of feature selectivities and maps in the mammalian primary visual cortex [0.03%]
哺乳动物初级视觉皮层特征选择性和投射的起源
Trichur R Vidyasagar,Ulf T Eysel
Trichur R Vidyasagar
A common feature of the mammalian striate cortex is the arrangement of 'orientation domains' containing neurons preferring similar stimulus orientations. They are arranged as spokes of a pinwheel that converge at singularities known as 'pin...
Martin Picard
Martin Picard
Communication is a central theme in biology. Consequently, specialized structures have evolved to permit rapid communication among cells, tissues, organs, and physiological systems, thus enhancing the overall function and adaptation of the ...
Stan B Floresco
Stan B Floresco
Varazzani and colleagues explored how noradrenergic and dopaminergic neural activity relates to cost/benefit decisions involving effort. They show these systems may play complementary roles in resolving these decisions; dopamine encodes cos...