The battle of the titans: Comparative performance of Kintelligence, microarray, and shotgun sequencing in ten Estonian cases with unidentified human remains [0.03%]
巨人之战：Kintelligence、微阵列和霰弹枪测序在十个爱沙尼亚身份不明遗骸案件中的比较性能
Monika Stoljarova-Bibb,Marie-Louise Kampmann,Jeppe D Andersen et al.
Monika Stoljarova-Bibb et al.
To conduct forensic investigative genetic genealogy (FIGG), reliable true-positive matches in genetic genealogy databases are required, which in turn depend on the generation of high-quality SNP profiles. This is particularly challenging fo...
Extending biogeographic ancestry inference to minor contributors in forensic DNA mixtures [0.03%]
法医DNA混合物中推断次要供体的生物地理想亲缘关系的方法
Géraldine Damour,Pierre Oppliger,Diana Hall
Géraldine Damour
DNA mixtures are common in forensic samples and limit the effectiveness of recently developed intelligence tools based on novel sequencing technologies, such as biogeographic ancestry prediction. DIP-STR markers, which combine a low-mutatio...
Preparing for shotgun sequencing in forensic genetics - Benchmarking of tools for read mapping, genotype calling, and imputation [0.03%]
测序技术在法医遗传学中的应用展望——基于读长定位、基因型识别和隐性标记的工具评估基准分析
Alberte Honoré Jepsen,Brando Poggiali,Martin Tuwel Jensen et al.
Alberte Honoré Jepsen et al.
Shotgun sequencing has emerged as a powerful tool in forensic genetics, as it allows for comprehensive genetic profiles to be generated from highly degraded DNA. The method enables simultaneous access to a wide range of markers, thereby sup...
Letter to the Editor Response to "Minimum FSI: Genetics requirements for publishing data on DNA transfer and recovery, given activities" [0.03%]
致编辑的信：关于“最低FSI：在给定活动情况下发布有关DNA转移和恢复的遗传要求”
Kathrin Broderius,Annica Gosch,Malte Bamberg et al.
Kathrin Broderius et al.
This is a response to the Editorial ""Minimum FSI: Genetics requirements for publishing data on DNA transfer and recovery, given activities" by Gill at el. ...
Simultaneous analysis of miRNA and 16S rDNA by a multiplex droplet digital PCR system for body fluid source identification [0.03%]
一种用于鉴定体液类型的多重微滴数字PCR系统及 simultaneou分析miRNA和16S rDNA的方法
Jingjing Xu,Niu Gao,Wenjing Hu et al.
Jingjing Xu et al.
Forensic body fluid identification, crucial for crime scene reconstruction, is often limited by sample scarcity and degradation. Hence, there is growing interest in more stable biomarkers like miRNA and microbial markers. While each has its...
A nanopore sequencing scheme for MiniHap markers and its application in kinship analysis [0.03%]
用于MiniHap标记的纳米孔测序方案及其在亲缘分析中的应用
Bo Liu,Qiang Zhu,Lanrui Jiang et al.
Bo Liu et al.
Kinship testing based on genetic correlation is one of the primary tasks in forensic genetics. Currently, microhaplotypes (MHs) have become a research hotspot in the field of forensic genetics. Traditional MHs are defined as tightly linked ...
Age-associated DNA methylation loci at lncRNA genomic regions revealed by Oxford Nanopore whole-genome sequencing using four methylation callers [0.03%]
基于牛津纳米孔全长基因组测序的四种甲基化调用算法在长链非编码 RNA 基因组区域揭示与年龄相关的 DNA 甲基化位点
Fatih Tiras,Christian Cole,Alexander Gray
Fatih Tiras
Accurate age inference from biological material is an essential component of forensic investigations. DNA methylation is a particularly informative biomarker, yet most current forensic approaches rely on bisulphite conversion, which can deg...
Erroneous D7S820 genotypes caused by X.1 artefact removal in ForenSeq™ UAS v2.7.0 and their impact on forensic analyses [0.03%]
ForenSeq™ UAS 分析软件v2.7.0中由于去除X.1信号所造成的D7S820基因座的错误分型及其对法医遗传学分析的影响
Alan Codoñer-Alejos,Sandra Carbó-Ramírez,Jorge Ruiz-Ramírez et al.
Alan Codoñer-Alejos et al.
The latest release of ForenSeq™ Universal Analysis Software (UAS), version 2.7.0, introduces several major upgrades, including the implementation of bracketed formatting for short tandem repeats (STRs) and adoption of the International Soc...
DNA methylation-based assay and Random Forest classification model for identification of biological materials [0.03%]
基于DNA甲基化鉴别人体组织的随机森林模型及检测试剂盒
Laura Schmelzer,Franz Haehn,Ulrike Schmidt et al.
Laura Schmelzer et al.
Determination of the biological origin of trace material is an important forensic tool for supporting crime investigations. Differentially methylated DNA positions (DMPs) can be used to discriminate among forensically relevant biological ma...