Quo vadis, BGA? A collaborative EDNAP exercise on the challenges and progress in forensic biogeographical ancestry inference [0.03%]
BGA的未来在哪里？一项关于法医生物地理祖先推断挑战与进展的EDNAP合作练习
Marta Diepenbroek,António Amorim,Katja Anslinger et al.
Marta Diepenbroek et al.
There is a broad consensus that forensic tests for the prediction of externally visible characteristics (EVC) and analysis of biogeographic ancestry (BGA) of an individual are technically reliable. However, interpretation of the results and...
KLINK: A program for kinship testing with pairwise linked STR markers [0.03%]
基于STR基因座进行亲缘关系检验的软件KLINK
Magnus D Vigeland,Siv Gilfillan
Magnus D Vigeland
We present KLINK, a free, user-friendly tool for forensic kinship testing that accommodates linkage between marker pairs and also advanced mutation models. This addresses a gap in existing software, which typically handles either linkage or...
Carlotta Cammareri,Claire Wagenaar,Abel de Wit et al.
Carlotta Cammareri et al.
In forensic DNA casework, complex trace samples may benefit from rework procedures involving additional PCR replicates and lowered analytical thresholds. These procedures may strongly increase or decrease the likelihood ratio (LR), simplify...
Quantitative DNA/RNA fragmentation assays for estimating the time since deposition (TsD) of bloodstains [0.03%]
定量DNA/RNA片段化测定用于估算血迹的沉积时间(TsD)
Hongxia He,Xiaoting Mo,Zhe Zhou et al.
Hongxia He et al.
The time since deposition (TsD) of bloodstains can provide crucial information for forensic casework, yet reliable estimation methods remain limited. This study aimed to identify an optimal quantitative PCR (qPCR) approach for bloodstain Ts...
Ensaya: An ensemble age model for prediction of chronological age in adolescents and young adults [0.03%]
Ensaya：一种预测青少年和年轻人Chronological年龄的集成模型
Kristina Stenløkk,Pål Skage Dahlberg,Veslemøy Rolseth et al.
Kristina Stenløkk et al.
DNA methylation-based models for chronological age estimation have, for over a decade, been among the most important methods for age prediction in humans. While large-scale data have enabled the development of numerous models, their accurac...
Comparison of key diagnostics for probabilistic interpretation of STR mixture data generated with length-based and MPS methodologies [0.03%]
基于长度和MPS方法学的STR混合数据的概率解释的关键诊断比较
Kyle Duke,Daniela Cuenca,Kevin Cheng et al.
Kyle Duke et al.
This study directly compared the mixture deconvolution performance of two probabilistic genotyping software applications: STRmix™ v2.8, which accepts length-based STR input data, and STRmix™ NGS v1.1.0, which accepts sequence-based STR in...
Likelihood Ratios Given Activity-Level Propositions for DNA Transfer Evidence: Theoretical Foundations of the HaloGen Framework (Part I) [0.03%]
基于活动水平命题的DNA遗传亲缘关系检验似然比计算（HALOGEN框架理论基础）（一）
Peter Gill,Øyvind Bleka
Peter Gill
The interpretation of trace DNA evidence at activity level requires explicit modelling of transfer, persistence, and the possibility that a relevant actor leaves no detectable DNA. We present the theoretical foundations of HaloGen, an open-...
Likelihood Ratios Given Activity-Level Propositions for DNA Transfer Evidence: Practical Implementation and Simulation Studies Using the HaloGen Engine (Part II) [0.03%]
基于活动水平命题的DNA遗传物质转移检验证据似然比计算及其在HaloGen引擎中的实现和模拟研究（二）
Peter Gill,Øyvind Bleka
Peter Gill
The quantitative interpretation of low-template DNA findings given activity-level propositions requires models that can accommodate inter-laboratory variability, uncertainty in transfer and recovery, and case-specific assumptions. This pape...
Forensic evaluation of 101 identity-informative SNPs in a Filipino population using massively parallel sequencing [0.03%]
基于大规模平行测序在菲律宾人群的101个身份识别SNP的法医学效能评估
Jazelyn M Salvador,Dame Loveliness T Apaga,Maeviviene V Sosing et al.
Jazelyn M Salvador et al.
DNA-based human identification traditionally relies on short tandem repeats (STRs) as the primary genetic markers for analysis. However, single nucleotide polymorphisms (SNPs), particularly identity-informative SNPs (iiSNPs) located on auto...
Reprocessing of hair roots using conventional forensic DNA analysis following RapidHIT® ID processing [0.03%]
使用常规法医DNA分析重复处理经过RapidHIT®ID系统处理的毛囊根部
Alicia Haines,Tabarek Aljumaili,David Bruce
Alicia Haines
Hair traces are frequently recovered at crime scenes and represent a valuable source of forensic DNA, although the cellular content of hair roots varies substantially depending on growth stage, with shed hairs typically containing limited D...