MatchY in practice: Factors influencing pedigree-based Y-STR match probabilities [0.03%]
基于谱系的Y-STR基因分型匹配概率计算：实例分析及影响因素探讨
Dion Zandstra,Amke Caliebe,Mohsen Ghanbari et al.
Dion Zandstra et al.
While widely applied in forensic practice, equating Y-STR match probabilities with haplotype frequencies derived from population databases has been considered inappropriate, as these databases cannot be representative of each and every case...
MitoFREQ: A novel approach for mitogenome frequency estimation from top-level haplogroups and single nucleotide variants [0.03%]
MitoFREQ：一种从顶级单倍群和单核苷酸多态性估计线粒体基因组频率的新方法
Mikkel Meyer Andersen,Nicole Huber,Kimberly Sturk-Andreaggi et al.
Mikkel Meyer Andersen et al.
Forensic lineage markers pose a challenge in forensic genetics as their evidential value can be difficult to quantify. Lineage marker population frequencies can serve as one way to express evidential value. However, for some markers, e.g., ...
Genetic analysis and in silico prediction of CACNA1S and RYR1 variants of sudden unexplained nocturnal death syndrome in Thai population [0.03%]
泰国人群中央导管相关性夜间突发性不明原因死亡的CACNA1S和RYR1基因变异的遗传分析及计算机预测研究
Ashfaque Ahmed Kanhar,Aummarin Chaloemthanetphong,Kiattawee Choowongkomon et al.
Ashfaque Ahmed Kanhar et al.
Sudden Unexplained Nocturnal Death Syndrome (SUNDS) is a lethal disorder with a largely elusive genetic etiology. While traditionally associated with cardiac channelopathies and cardiomyopathies, the role of skeletal muscle excitation-contr...
Identifying unknown contributors to two-person DNA mixtures via whole-genome sequencing [0.03%]
通过全基因组测序识别两个人DNA混合物中的未知供者
Yuting Lei,Zhen Liu,Shuang Han et al.
Yuting Lei et al.
Forensic investigative genetic genealogy (FIGG) has demonstrated considerable promise in identifying perpetrators and unidentified human remains. While whole-genome sequencing (WGS) offers a robust foundation for FIGG, DNA mixtures-prevalen...
Improving accessibility of species identification for wildlife crime prosecution: Expanding WildSEQ for calcified and keratinised materials [0.03%]
改善野生动植物犯罪鉴定的物种识别的可访问性：扩大WildSEQ（针对钙化和角蛋白材料）
O Yugovich,V Cave,S Sturrock et al.
O Yugovich et al.
The growing need for simplified and accessible species identification methods is critical for supporting the prosecution of illegal wildlife trafficking. This requires the development of approaches suitable for implementation across both we...
A triplex RPA-LFA assay for the simultaneous detection of forensically important necrophagous insects in complex DNA mixtures [0.03%]
一种三联体RPA-LFA检测试剂盒同时检测复杂DNA混合物中重要的法医腐败昆虫的方法
Fengqin Yang,Xuan Tang,Dan Wen et al.
Fengqin Yang et al.
Accurate species identification of necrophagous insects is crucial in forensic investigations. To overcome the limitations of complex morphological identification-especially for larval stages-and time-consuming DNA sequencing methods, we de...
Non-parametric simulation of DNA mixture profiles from one-person trace profiles [0.03%]
基于单人微量样本的DNA混合图谱非参数模拟方法研究
Kai Budrikas,Klaas Slooten
Kai Budrikas
Evidential test data of genotyping softwares must clearly carry the characteristics of real-life evidential trace profiles. Ensuring that simulated data, which is used in research and validation, is similar and behaves similarly to real-lif...
Can DNA withstand the test of time? Exploring degradation across storage conditions [0.03%]
DNA能否经受时间的考验？探究不同保存条件下的降解情况
Giulia Sguazzi,Eugenio Alladio,Selena Cisana et al.
Giulia Sguazzi et al.
The integrity of DNA extracts is a critical factor in forensic genetics, particularly when DNA represents the sole source of evidentiary value in criminal investigations. Although technologies such as mini-STRs have improved the amplificati...
Who packed the drugs? Improved DNA recovery and its impact on findings given activity-level propositions [0.03%]
谁做了案？改进DNA提取方法及其对活动水平命题调查结果的影响
Sara Faria,Peter Gill,Ana Clara Ribeiro et al.
Sara Faria et al.
The interpretation of forensic DNA findings given activity-level propositions depends on the processes governing DNA transfer, persistence, and recovery, as well as on the laboratory methods used to recover DNA. This study investigated the ...
Advancing forensic SNP typing: Insights from an interlaboratory study of the FORCE panel [0.03%]
法医SNP分型研究的进展：FORCE基因座板多个实验室实验的启示
Andreas Tillmar,Kimberly Sturk-Andreaggi,Adam Staadig et al.
Andreas Tillmar et al.
This study evaluated the ability to produce FORensic Capture Enrichment (FORCE) genotypes using amplicon-based and capture-based enrichment assays. The FORCE panel is a standardized set of single nucleotide polymorphism (SNP) markers develo...