Corrigendum to "DNA methylation profiling for a confirmatory test for blood, saliva, semen, vaginal fluid and menstrual blood" [Forensic Sci. Int. Genet. 24 (2016) 75-82] [0.03%]
“基于DNA甲基化分型的血液、唾液、精斑、阴道分泌物及月经血确认检验”一文勘误通知书
Hwan Young Lee,Sang-Eun Jung,Eun Hee Lee et al.
Hwan Young Lee et al.
Transferring a microhaplotype-specific probabilistic genotyping model from targeted amplification to hybridization capture: A proof-of-concept study of a 100-locus panel for DNA mixtures [0.03%]
一种将靶向扩增特异性微等位基因概率分型模型转移到杂交捕获上的概念验证研究：用于DNA混合物的100个遗传标记面板
Chun Yang,Yueyan Cao,Yuting Wang et al.
Chun Yang et al.
Probabilistic genotyping (PG) has become the standard framework for evaluating forensic DNA mixtures, yet most implementations were developed for STR data and PCR-based enrichment. Microhaplotypes (MHs) provide high allele diversity without...
Targeting ultrashort fragments: Development and validation of a 44-InDel panel for highly degraded DNA [0.03%]
靶向超短片段：针对高度降解DNA的44个InDel基因座_panel的研发与验证
Ye Li,Yuepeng Wang,Xiaoyi Fu et al.
Ye Li et al.
Degraded samples are common yet challenging evidence types in forensic casework, and obtaining complete profiles from highly degraded samples has long been a major difficulty in forensic DNA analysis. However, there is a lack of effective m...
SiMSen-Seq STR sequencing across five laboratories enables lowered noise thresholds and improved allele calling [0.03%]
五个实验室的SiMSen-Seq检测使STR测序能够降低噪音并提高等位基因判断的准确性
Arvid H Gynnå,Maja Sidstedt,Kevin M Kiesler et al.
Arvid H Gynnå et al.
Unique molecular identifiers (UMI) can be used in forensic STR sequencing to reduce the level of analytical artifacts. Here, we perform an interlaboratory study across five independent sites where the previously developed UMI-based SiMSen-S...
COSA: A consolidated methylation-based prediction panel for body fluid/tissue of origin, smoking status, and chronological age using amplicon-based massively parallel sequencing [0.03%]
COSA：一种基于甲基化的预测板，用于身体液体/组织起源、吸烟状况和生物学年龄的评估，使用扩增子大规模平行测序
Soo-Bin Yang,Ga Hyung Kim,Moon Hyun So et al.
Soo-Bin Yang et al.
DNA methylation at CpG sites has emerged as a powerful epigenetic biomarker for predicting forensically relevant traits, including chronological age, the biological origin of forensic samples encompassing body fluid and tissue sources, and ...
DNA tests for ancestry and phenotype inference applied to the UK Metropolitan Police Operation Minstead: The investigation of serial sex offender Delroy Grant [0.03%]
应用于英国大都会警察机关Minstead行动的祖先和表型鉴定的DNA检测：对系列性罪犯Delroy Grant的调查研究
C Phillips,A Rodriguez,A Gómez-Tato et al.
C Phillips et al.
SNP analysis in forensic genetics has expanded substantially over the past two decades, particularly for ancestry inference and forensic DNA phenotyping (FDP). However, interpretation of data from such analyses in complex, admixed populatio...
Uncovering mixture inversion: The prevalence of non-handlers as major contributors in forensic DNA evidence [0.03%]
揭开混合斑中的“隐匿个体”现象——非供体在法医DNA检材中的高占比贡献分析研究
Helen Roebuck,Roland A H van Oorschot,Bianca Szkuta et al.
Helen Roebuck et al.
This study presents the first systematic review examining the prevalence of DNA mixture inversion, defined as the occurrence of a major contributor to a DNA profile generated through indirect transfer via an intermediary individual. Followi...
Evaluating relationship inference from low-quality DNA using a conditional simulation framework [0.03%]
基于条件模拟框架评估低质量DNA的亲属关系推断
Alberte Honoré Jepsen,Marie-Louise Kampmann,Andreas Tillmar et al.
Alberte Honoré Jepsen et al.
Inference of genetic relationships from genomic data is central to applications in human, plant, and conservation genetics, with investigative genetic genealogy (IGG) increasingly used in forensic and population studies. While high-quality ...
Are genetically defined "metapopulations" self-evident in YHRD? [0.03%]
在YHRD中，根据基因型定义的“元种群（meta- population）”是显而易见的吗？
Tóra Oluffa Stenberg Olsen,Mikkel Meyer Andersen,James Curran et al.
Tóra Oluffa Stenberg Olsen et al.
In forensic genetics, the evidential value of a match between the Y-chromosomal short tandem repeat (Y-STR) profiles of a trace and a suspect is typically quantified by the frequency of the profile in a population database, particularly the...
Reduced amplification and amplicon dropout in PCR-based mitochondrial DNA massively parallel sequencing kits [0.03%]
基于PCR的线粒体DNA大规模平行测序试剂盒中的扩增减弱和amplicon丢失现象
Lourdes Prieto,Masinda Nguidi,Christina Amory et al.
Lourdes Prieto et al.
The highly polymorphic nature of mitochondrial DNA (mtDNA) poses a significant challenge for primer design in PCR-based assays, because mismatches under primer binding sites can lead to reduced amplification and thus lower sequencing read d...