Transcription and microbial profiling of body fluids using a massively parallel sequencing approach [0.03%]
采用高通量测序技术分析和表征人体体液中的微生物群落
Andrea Patrizia Salzmann,Giancarlo Russo,Sirisha Aluri et al.
Andrea Patrizia Salzmann et al.
Analysis of biological evidence typically begins with a preliminary screening for the presence of biological fluids, traditionally with enzymatic or immunologic tests and of late by RNA profiling. The goal of this study was to create a whol...
Laura Otten,Sabrina Banken,Marianne Schürenkamp et al.
Laura Otten et al.
With the development of highly sensitive STR profiling methods, combined with sound statistical tools, DNA analysis on the (sub-)source level is hardly ever seriously questioned in court. More often, the exact mode of DNA transfer to the cr...
Demonstration of a mitochondrial DNA-compatible workflow for genetically variant peptide identification from human hair samples [0.03%]
一种适用于线粒体DNA的_workflow_以鉴定来自人类头发样本的遗传变异肽的演示
L A Catlin,R M Chou,Z C Goecker et al.
L A Catlin et al.
Hair is an evidentiary sample that typically does not provide sufficient nuclear DNA for forensic analysis. Therefore, state-of-the-art forensic examination for hair samples include subjective microscopic evaluation, mitochondrial DNA (mtDN...
A novel phylogenetic approach for de novo discovery of putative nuclear mitochondrial (pNumt) haplotypes [0.03%]
一种新颖的系统发育方法，用于从头发现潜在的核线粒体（pNumt）单倍型
Utpal Smart,Bruce Budowle,Angie Ambers et al.
Utpal Smart et al.
Current approaches for parsing true variation (i.e. signal) from noise, broadly involve estimating a baseline value of the latter, below which all sequence data are ignored. In an effort to deliver a more objective criterion for setting suc...
Analysis of Uyghur and Kazakh populations using the Precision ID Ancestry Panel [0.03%]
利用Precision ID-Ancestry Panel分析维吾尔族和哈萨克族人群
H Simayijiang,C Børsting,T Tvedebrink et al.
H Simayijiang et al.
Autosomal ancestry informative markers (AIMs) are important markers for inferring ancestry of humans. In the present study, we typed 105 Uyghurs and 94 Kazakhs with the Precision ID Ancestry Panel that amplifies 165 autosomal AIMs. No stati...
Elaine Y Y Cheung,Christopher Phillips,Mayra Eduardoff et al.
Elaine Y Y Cheung et al.
The use of microhaplotypes (MHs) for ancestry inference has added to an increasing number of ancestry-informative markers (AIMs) for forensic application that includes autosomal single nucleotide polymorphisms (SNPs) and insertions/deletion...
Magdalena M Buś,Maria Lembring,Anna Kjellström et al.
Magdalena M Buś et al.
In 1998, a Viking Age mass grave was discovered and excavated at St. Laurence´s churchyard in Sigtuna, Sweden. The excavated bones underwent osteoarchaeological analysis and were assigned to at least 19 individuals. Eleven skeletons showed...
Base specific variation rates at mtDNA positions 16093 and 16183 in human hairs [0.03%]
人头发中mtDNA的两个位点16093和16183的变异率
Stijn Desmyter,Sophie Dognaux,Fabrice Noel et al.
Stijn Desmyter et al.
Small variations between haplotypes detected in different tissues from the same individual have been previously described. These differences complicate the interpretation of mtDNA results in real forensic casework. mtDNA haplotypes detected...
Pilot study for forensic evaluations of the Precision ID GlobalFiler™ NGS STR Panel v2 with the Ion S5™ system [0.03%]
用于全球基因图谱NGS检测的法医研究试点工作
Ruiyang Tao,Wenjie Qi,Chong Chen et al.
Ruiyang Tao et al.
With the continuous development of massively parallel sequencing (MPS), increasing numbers of laboratories have utilized this method for forensic genomic analyses. When sequencing common short tandem repeats (STRs), MPS does have many advan...
Development and validation of the EUROFORGEN NAME (North African and Middle Eastern) ancestry panel [0.03%]
EUROFORGEN-NAME（北非和中东）祖源检测芯片的构建及验证
V Pereira,A Freire-Aradas,D Ballard et al.
V Pereira et al.
Inference of biogeographic origin is an important factor in clinical, population and forensic genetics. The information provided by AIMs (Ancestry Informative Markers) can allow the differentiation of major continental population groups, an...