Metabolic syndrome necroptosis: disease implications and therapeutic targeting [0.03%]
代谢综合征坏死性凋亡：疾病影响与靶向治疗
Jiaenli Bolati,Ahequeli Gemingnuer,Fang Lu et al.
Jiaenli Bolati et al.
Necroptosis is a regulated form of cell death characterized by receptor-interacting protein kinase (RIPK) activation, leading to necrosome formation and subsequent membrane rupture. Increasing evidence indicates that necroptosis contributes...
Irisin/PGC-1-α improves acute kidney injury by enhancing autophagy and regulating lipid metabolism [0.03%]
irisin/pgc-1-α通过增强自噬和调节脂质代谢改善急性肾损伤
Jinrun Han,Hailin Yang,Fangning Liu et al.
Jinrun Han et al.
Combined functional lipids modulate lipid metabolism and attenuate metabolic dysregulation in a rat model of cafeteria diet [0.03%]
功能脂质调节血脂代谢及改善西式膳食大鼠模型的代谢紊乱作用研究
Candela L Suppo,Gisela N Kuhn,Jimena V Lavandera et al.
Candela L Suppo et al.
Comprehensive analysis and therapeutic implications of prognostic value of circadian rhythm genes in hepatocellular carcinoma [0.03%]
肝癌中昼夜节律基因预后价值的全面分析及治疗启示
Jichun Sun,Jiaxing Hou,Hongbo Xu et al.
Jichun Sun et al.
Concurrent initiation of treadmill exercise protects against angiotensin II-induced renal injury by modulating oxidative stress and autophagy in mice [0.03%]
同时进行跑步运动通过调节氧化应激和自噬减轻血管紧张素Ⅱ致小鼠肾损伤
Kyung-Wan Baek,Jong-Hwa Won,Ying-Ying Xiang et al.
Kyung-Wan Baek et al.
From molecular mechanisms to nutritional applications: protein and polyphenol interventions in sarcopenia [0.03%]
从分子机制到营养应用：蛋白质和多酚在肌少症中的干预作用
Patricia Aragón-Espinosa,Patricia Pérez-Matute,Catherine Bompart et al.
Patricia Aragón-Espinosa et al.
Sarcopenia, the progressive loss of skeletal muscle mass and function, represents a major public health concern due to its impact on mobility, independence, and quality of life, especially in oldadults. Current treatment strategies primaril...
Resveratrol and dexamethasone have cell-specific effects on the circadian clock but not on the rhythm of mitochondrial function in the fetal heart [0.03%]
白藜芦醇和地塞米松对胎儿心脏的昼夜节律钟具有细胞特异性作用，但并非对线粒体功能节律如此
Dmytro Semenovykh,Kateryna Semenovykh,Martin Sládek et al.
Dmytro Semenovykh et al.
Proper development of the heart during the fetal period is a prerequisite for health in later life. It was shown that maternal supplementation with stilbenoid resveratrol (RES) is beneficial for cardiovascular function. Synthetic glucocorti...
Exercise training reinforces the therapeutic efficacy of bone marrow-derived mesenchymal stem cell transplantation for ventricular ectopy and myocardial infarction injury [0.03%]
运动训练增强骨髓间充质干细胞移植治疗室性心律失常及心肌梗死损伤的疗效
Shirin Abazari,Seyed Abdollah Hashemvarzi,Kamal Ranjbar
Shirin Abazari
This study investigated the synergistic effect of early bone marrow-derived mesenchymal stem cells (BM-MSC) transplantation and endurance training on exercise-induced ventricular ectopy, myocardial infarction-induced injury and cardiac func...
Protective effect of melatonin against age-related ischemia-reperfusion injury is associated with the NLRP3 inflammasome pathway [0.03%]
褪黑素通过NLRP3炎症小体途径对抗年龄相关的缺血再灌注损伤的保护作用
Ikram Ben Jeddou,Ángela Berlana,Esther Rey et al.
Ikram Ben Jeddou et al.
Aging heightens susceptibility to ischemia-reperfusion (IR) injury, complicating liver transplantation, while the nucleotide-binding oligomerization domain (NOD)-like receptor pyrin domain containing 3 (NLRP3) inflammasome drives IR- and ag...
Liver fibrosis and type 2 diabetes modulate postprandial incretin and glucagon responses in fatty liver disease [0.03%]
肝纤维化和2型糖尿病会调节脂肪肝病的餐后肠促胰素和胰高糖素反应
Brenno Astiarraga,Adrià Rodriguez-Castellano,Victoria Ceperuelo-Mallafré et al.
Brenno Astiarraga et al.
The study aims to characterize the secretion dynamics of glucagon-related peptides, including GLP-1, GIP, and GLP-2, across different stages of metabolic-associated steatotic liver disease (MASLD), while evaluating the impact of type 2 diab...