Anxiety-related attentional characteristics and their relation to freezing of gait in people with Parkinson's: Cross-validation of the Adapted Gait Specific Attentional Profile (G-SAP) [0.03%]
焦虑相关注意特征及其与帕金森病患者冻结步态的关系:适应性步态特异性注意特征量表(G-SAP)的跨验证
Uri Rosenblum,Adam J Cocks,Meriel Norris et al.
Uri Rosenblum et al.
BackgroundAnxiety often exacerbates freezing of gait (FOG) in people with Parkinson's (PwP). Anxiety-related attentional processes and associated processing inefficiencies, like conscious movement processing (CMP) and ruminations, can subst...
Sex-specific progression of Parkinson's disease: A longitudinal mixed-models analysis [0.03%]
基于纵向混合效应模型分析帕金森病的性别差异特征
Anne-Marie Hanff,Christopher McCrum,Armin Rauschenberger et al.
Anne-Marie Hanff et al.
BackgroundDespite its relevance, the clinical progression of motor- and non-motor symptoms associated with Parkinson's disease (PD) is poorly described and understood, particularly in relation to sex-specific differences in clinical progres...
Effects of theta burst stimulation on the Parkinsonian gait disorder and cortical gait-network activity [0.03%]
经颅磁theta burst刺激对帕金森病步态障碍及皮层步态网络的影响
Janina Dutke,Jonas Gehlenborg,Miriam Heise et al.
Janina Dutke et al.
BackgroundThe Parkinsonian gait disorder and freezing of gait (FoG) are challenging symptoms of Parkinson's disease (PD).ObjectiveTo assess the effect of subthalamic theta burst deep brain stimulation (TBS-DBS) on the Parkinsonian gait perf...
Visual hallucinations in Parkinson's disease are associated with deficits in social perception [0.03%]
视觉假象与帕金森病的社会知觉缺陷有关
Louis Albert,Neza Vehar,Jevita Potheegadoo et al.
Louis Albert et al.
BackgroundMost structured visual hallucinations (VH) in Parkinson's disease (PD) involve animate-social objects, yet current theories fail to account for the prominent social component of VH in PD.ObjectiveTo study social perception in PD p...
Early thinking palliative care for people with Parkinson's disease: A thematic synthesis based on a systematic mixed-methods review [0.03%]
帕金森病患者的早期姑息治疗思考:基于系统混合方法回顾的语义综合主题分析
Michela Garon,Christiane Weck,Valentina Leta et al.
Michela Garon et al.
BackgroundParkinson's disease is a progressive neurodegenerative disorder. Awareness and the evidence supporting the merits of palliative care (PC) approaches to people with Parkinson's disease (PwP) are increasing.ObjectiveThis review aime...
One-year practice effects predict long-term cognitive outcomes in Parkinson's disease [0.03%]
帕金森病一年的练习效果预测长期的认知结果
Sofía Avila Pérez,Vincent Koppelmans,Kevin M Duff et al.
Sofía Avila Pérez et al.
Background: Predicting which individuals with Parkinson's disease (PD) will develop cognitive deficits is challenging, but important towards selecting those individuals at higher risk of progression for personalized early intervention and e...
Dementia risk prediction in early Parkinson's disease: Validation and genetic integration of the Montreal Parkinson risk of dementia scale (MoPaRDS) [0.03%]
早期帕金森病患者痴呆风险预测:莫诺特帕金森痴呆风险评分量表(MoPaRDS)的验证及遗传因素整合分析
Aleksandra A Szwedo,Ingvild Dalen,Rachael A Lawson et al.
Aleksandra A Szwedo et al.
BackgroundPrediction models for dementia in Parkinson disease (PD) are needed to better identify high-risk patients, but existing risk models often lack validation in early-stage PD, when prognosis is most challenging.ObjectiveThis study ai...
Use of β-adrenoreceptor drugs and Parkinson's disease incidence in women from the French E3N cohort study [0.03%]
法国E3N队列研究中β-肾上腺素受体药物使用与女性帕金森病发病率的关系
Thi Thu Ha Nguyen,Agnès Fournier,Émeline Courtois et al.
Thi Thu Ha Nguyen et al.
BackgroundExperimental and observational studies suggest that β-adrenoreceptor drugs (β2-agonists/β-antagonists) are associated with Parkinson's disease (PD) risk. Previous epidemiological studies may be hampered by reverse causation/con...
Preparing for Parkinson's disease prevention trials: Current progress and future directions [0.03%]
备战帕金森病预防试验——目前进展与未来方向
Sarah Bouhadoun,Aline Delva,Michael A Schwarzschild et al.
Sarah Bouhadoun et al.
In recent decades, numerous clinical trials have aimed to delay or prevent Parkinson's disease (PD) progression. Despite the theoretical promise and encouraging preclinical data, none have shown clear efficacy in slowing or preventing PD pr...
From past to future: Digital approaches to success of clinical drug trials for Parkinson's disease [0.03%]
从过去到未来:帕金森病临床试验成功的数字方法
Cen Cong,Madison Milne-Ives,Ananya Ananthakrishnan et al.
Cen Cong et al.
Recent years have seen successes in symptomatic drugs for Parkinson's disease, but the development of treatments for stopping disease progression continues to fail in clinical drug trials, largely due to the lack of clinical efficacy of dru...