Sukesh R Bhaumik
Sukesh R Bhaumik
TAP-MS analysis of FACT interactions and regulation by a ubiquitin ligase, San1 [0.03%]
FACT互作及由泛素连接酶San1调控的Tap-MS分析
Priyanka Barman,Pritam Chakraborty,Shalini Guha et al.
Priyanka Barman et al.
An evolutionarily conserved heterodimeric FACT (Facilitates chromatin transcription) regulates transcription, DNA repair, replication and other cellular processes via its interactions with other proteins. FACT is recently found to be regula...
Susceptibility to pseudoexfoliation linked to intronic variant rs4926246 in CACNA1A: Evidence from an Indian population study [0.03%]
印度人群研究中CACNA1A内含子多态性rs4926246与伪假体排出症易感性的关联证据
Bushra Hayat,Swagatika Panigrahi,Senjit Ram Behera et al.
Bushra Hayat et al.
Pseudoexfoliation (PEX) is an age-related, complex systemic disorder of protein aggregopathy. It is characterized by the extracellular fibril depositions, termed PEX fibrils, initially observed in various organ tissues during pseudoexfoliat...
Transcriptional responses of three slc39a/zip members (zip4, zip5 and zip9) and their roles in Zn metabolism in grass carp (Ctenopharyngodon idella) [0.03%]
三种铁锌转运蛋白家族成员(zip4、zip5和zip9)的转录组响应及其在草鱼锌代谢中的作用
Jia-Cheng Guo,Peng-Cheng Xu,Yi-Chuang Xu et al.
Jia-Cheng Guo et al.
In order to explore the regulatory mechanism of zip4, zip5 and zip9 in zinc metabolism of grass carp (Ctenopharyngodon idella), the effects of zinc (Zn) on the mRNA expression of zip4, zip5 and zip9 were investigated. Compared to the contro...
Experimental approaches to investigate biophysical interactions between homeodomain transcription factors and DNA [0.03%]
研究家园域转录因子与DNA之间生物物理相互作用的实验方法
Fadwa Mekkaoui,Robert A Drewell,Jacqueline M Dresch et al.
Fadwa Mekkaoui et al.
Homeodomain transcription factors (TFs) bind to specific DNA sequences to regulate the expression of target genes. Structural work has provided insight into molecular identities and aided in unraveling structural features of these TFs. Howe...
Competing endogenous RNAs network and therapeutic implications: New horizons in disease research [0.03%]
竞争性内源RNA网络及治疗意义：疾病研究的新视野
Nahla E El-Ashmawy,Eman G Khedr,Renad T Darwish et al.
Nahla E El-Ashmawy et al.
Different diseases may arise from the dysregulation of non-coding RNAs (ncRNAs), which regulation is necessary for maintaining cellular homeostasis. ncRNAs are regulated by transcriptional, post-transcriptional, translational and post-trans...
Bioinformatic meta-analysis of transcriptomics of developing Drosophila muscles identifies temporal regulatory transcription factors including a Notch effector [0.03%]
对发育中的果蝇肌肉的转录组学进行生物信息综合分析，确定了包括一个Notch效应物在内的时间调控转录因子
Amartya Mukherjee,Fathima Ashraf,Upendra Nongthomba
Amartya Mukherjee
The intricate mechanism of gene regulation coordinates the precise control of when, where, and to what extent genes are activated or repressed, directing the complex processes that govern cellular functions and development. Dysregulation of...
BCL11b interacts with RNA and proteins involved in RNA processing and developmental diseases [0.03%]
BCL11B与参与rna加工和发育疾病的rna及蛋白质相互作用
Haitham Sobhy,Marco De Rovere,Amina Ait-Ammar et al.
Haitham Sobhy et al.
BCL11b is a transcription regulator and a tumor suppressor involved in lymphomagenesis, central nervous system (CNS) and immune system developments. BCL11b favors persistence of HIV latency and contributes to control cell cycle, differentia...
Human stem cell-specific epigenetic signatures control transgene expression [0.03%]
人类干细胞特异的表观遗传谱系控制转基因表达
Chulhwan S Kwak,Furkan E Oflaz,Jiamin Qiu et al.
Chulhwan S Kwak et al.
Human stem cell-derived models have emerged as an important platform to study tissue differentiation and disease mechanisms. Those models could capitalize on biochemical and cell biological methodologies such as omics, autophagy, and organe...
EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis? [0.03%]
EB病毒感染改变人结肠细胞的DNA甲基化：通向炎症和癌变的道路？
Roberta Santarelli,Giuseppe Rubens Pascucci,Salvatore Lo Presti et al.
Roberta Santarelli et al.
Epstein-Barr Virus (EBV) is associated with several types of human cancers, and changes in DNA methylation are reported to contribute to viral-driven carcinogenesis, particularly in cancers of epithelial origin. In a previous study, we demo...