A double-blind randomised controlled trial assessing the effect of menaquinone producing probiotics on vitamin K status [0.03%]
M Muilwijk,S Kremers,L J Schurgers et al.
M Muilwijk et al.
This double-blinded randomised controlled trial investigated whether menaquinones (MK) producing probiotics for 12 weeks improve vitamin K status, compared with placebo in 50-75 years old with at least one cardiovascular risk factor. Twenty...
Effects of fermented milk containing Lacticaseibacillus paracasei strain Shirota on constipation and gut microbiota: A randomised pilot study in Vietnam [0.03%]
V Hoang Van,T Dong Van,N Nguyen Bao et al.
V Hoang Van et al.
Fermented milk containing Lacticaseibacillus paracasei strain Shirota (LcS) has been shown to improve stool consistency in various countries; however, its effect on hard or lumpy stools (HLS) in the Vietnamese population remains unclear. We...
The effects of probiotics supplementation on serum markers of oxidative stress in relapsing-remitting multiple sclerosis: a randomised, double-blind, placebo-controlled clinical trial [0.03%]
益生菌补充对复发缓解型多发性硬化症患者血清氧化应激标志物影响的随机双盲安慰剂对照试验
N Mohy,S Sanaie,S Rahnemayan et al.
N Mohy et al.
Oxidative stress is a significant contributor to neuronal damage in multiple sclerosis (MS), marked by an imbalance in reactive oxygen species and antioxidant defences. Probiotics may modulate oxidative stress and improve antioxidant levels...
Lactiplantibacillus plantarum LP4 alleviates alcoholic liver disease in C57BL/6 mice [0.03%]
植物乳杆菌LP4可减轻C57BL/6小鼠酒精性肝病
L Liu,X Tian,S Hao et al.
L Liu et al.
Chronic alcoholism can result in alcoholic liver disease. Current treatment methods for alcoholic liver injury primarily include abstinence, drug therapy, and surgical treatment. However, these methods have their own shortcomings - abstinen...
Obesity and the gut microbiota in the Middle East: a cross-cultural study of Lebanese and Emirati adults [0.03%]
中东的肥胖与肠道微生物群：黎巴嫩人和阿联酋成年人的跨文化研究
M Ali Ahmad,M Abou-Samra,E Blaak et al.
M Ali Ahmad et al.
Obesity is a growing public health concern in the Middle East and North Africa (MENA) region, yet limited research has explored how gut microbiota varies between Arab populations. This study compared the gut microbiota composition and diver...
Effects of a Bacillus subtilis HU58 and Heyndrickxia faecalis SC208 spore-forming probiotic formula on gastrointestinal health: results of a randomised, double-blind, placebo-controlled pilot study [0.03%]
枯草杆菌和两联球菌SP株式芽孢益生菌配方对中国人的肠道健康的影响：一项随机、双盲、安慰剂对照试点研究的结果
K Sorensen,S Khanna,A Porwal et al.
K Sorensen et al.
Irritable bowel syndrome (IBS) is a chronic functional disorder characterised by abdominal pain and altered bowel habits. The most prevalent subtype is diarrhoea-predominant IBS (IBS-D). The combination of Bacillus subtilis HU58 and Heyndri...
Targeted detection of microbes in synbiotic medical foods SBD111 and SBD121 to evaluate gut persistence: a randomised, open label trial [0.03%]
一种针对合生元医疗食品SBD111和SBD121中微生物的目标检测方法，以评估肠道定植：一项随机开放标签试验
K J Miller,I M Wolff,L A Montes de Oca Valeriano et al.
K J Miller et al.
The viability and persistence of orally administered microbes in the human gut are essential to their biological function. We previously described the development of two synbiotic medical foods, SBD111 and SBD121, each comprising four food-...
A pragmatic approach to integrate evidence-based medicine and personalized medicine: the example of personalized microbiome-targeting interventions [0.03%]
一种实用的方法来结合循证医学和个性化医学：以针对肠道菌群的个性化干预为例
D Zeilstra,A A Te Velde,G Remmers et al.
D Zeilstra et al.
Health care practitioners (HCPs) strive to provide the best medical care for each individual patient. The question as to what constitutes 'the best' does, however, not have a single straightforward answer. Evidence-based Medicine (EBM) and ...
Evaluation of antioxidant activity of novel potential probiotic cocktail in mice model of gut inflammation via oxidative stress-related pathways [0.03%]
评估新型潜在益生菌混合制剂在小鼠肠道炎症模型中的抗氧化活性及相关氧化应激通路的影响
N Rezaie,S Aghamohammad,F Bagheri-Amiri et al.
N Rezaie et al.
Oxidative stress plays a key role in colitis, a type of Inflammatory Bowel Disease, particularly when associated with a high-fat diet (HFD). Probiotics are known to alleviate inflammation through multiple mechanisms. This study aimed to eva...
Investigating therapeutic efficacy of Lactobacillus salivarius GZLC1 on colitis by examining its effects on intestinal fungi, antioxidant capacity, and inflammatory response in mice [0.03%]
通过检测小鼠肠道真菌、抗氧化能力和炎症反应的影响研究植物乳杆菌GZLC1治疗肠炎的疗效
J Ma,D Wu,M Liu et al.
J Ma et al.
We investigated the therapeutic potential of Lactobacillus salivarius in colitis mice, and the mice were randomly allocated into three groups with each consisting of 10 mice (n = 10): a control group (CSG), a DSS-induced colitis model group...