The immunomodulatory effects of Bifidobacterium lactis XLTG11 on cyclophosphamide-induced immune dysfunction in mice [0.03%]
鼠蹊磷酰胺致免疫功能障碍的乳双歧杆菌XLTG11的免疫调节作用
S Zhang,L Lian,H Yu et al.
S Zhang et al.
Previous studies have demonstrated that Bifidobacterium lactis (B. lactis) XLTG11 exerts significant immunomodulatory effects. However, the underlying mechanisms remain unclear. To investigate these mechanisms, BALB/c mice were randomly div...
The effects of a postbiotic supplement on biomarkers of microbiome, gastrointestinal, cardiometabolic, and immunometabolic health [0.03%]
一种后生物补充剂对微生物组、胃肠、心血管代谢和免疫代谢健康生物标志物的影响
C J Delebecque,M B La Monica,D Keller et al.
C J Delebecque et al.
The gut microbiome is increasingly recognised as a modifiable contributor to metabolic, immune, and stress-related physiology, yet many nutritional interventions produce broad microbial shifts that may be poorly tolerated. We investigated t...
Mechanistic characterisation of a novel oat-based postbiotic: microbiome modulation, barrier protection, and wound healing [0.03%]
一种新型燕麦后生物制品的机制特征：调节微生物组、保护屏障和促进伤口愈合
A Aditya,M J Koenigsknecht,C J Delebecque et al.
A Aditya et al.
Postbiotics, the inactivated microorganisms and their products derived from fermentation, represent an evolution in the rapidly growing biotics industry and extend health benefits without the need for bacterial viability. In this study, we ...
Harnessing microbial modulators to mitigate antibiotic-induced gut dysbiosis: from phytochemicals to faecal microbiota transplantation [0.03%]
利用微生物调节剂来缓解抗生素引起的肠道菌群失调：从中草药到粪便微生物移植
Q Wang,W Zhong,H Huang et al.
Q Wang et al.
Antibiotics remain indispensable for the management of infectious diseases; however, their use inevitably perturbs the gut microbiota. Advances in metagenomics and multiomics approaches have demonstrated that antibiotic exposure profoundly ...
A lysate of a multi-strain probiotic formulation inhibits cell growth and oxidative phosphorylation in colorectal cancer cells via a ceramide-mediated mechanism [0.03%]
一种多菌株益生菌制剂的裂解物通过诱导细胞内鞘氨醇从而抑制结直肠癌细胞生长和氧化磷酸化作用
D Gnocchi,F Lombardi,B Cinque et al.
D Gnocchi et al.
The multi-strain probiotic formulation (MPF - Oxxyslab™) regulates several biological processes, including oxygenation in human and mouse models of neurodegenerative diseases. Its effect on oxidative metabolism of tumour cells has not yet ...
Gut microbial differences and function in infants with gastroschisis: a pilot prospective cohort study [0.03%]
胃外翻婴儿肠道微生物差异及功能的前瞻性队列研究
K M Strobel,S L Leibel,S Bhute et al.
K M Strobel et al.
Newborns with gastroschisis hospitalised in the neonatal intensive care unit (NICU) are at risk for a disrupted gut microbiome. Infants with gastroschisis are particularly vulnerable to a dysbiotic microbiome; they require prolonged parente...
Infant gut microbiota composition and metabolism can be influenced by extensively hydrolysed casein in vitro [0.03%]
酪蛋白部分水解物对婴儿肠道菌群组成的体外影响研究
G Gross,I Bobeldijk-Pastorova,A M T Ouwens et al.
G Gross et al.
Composition of the gut microbiota, and related short chain fatty acids (SCFAs) production can influence allergic status. Extensively hydrolysed casein (eHC) infant formulas are used for management of cow's milk protein (CMP) allergy; howeve...
Gut commensal Bacteroides faecichinchillae, a potential novel candidate of next-generation probiotics targeting type 2 diabetes [0.03%]
结直肠癌肠道共生菌拟杆菌门费氏毛软粪球菌可能是下一代糖尿病益生菌候选菌
M Godet,E Delmas,C Gérard et al.
M Godet et al.
The implication of gut microbiota in the pathophysiology of type 2 diabetes, one of the major health concerns worldwide, has demonstrated the benefits of using probiotics to improve dysbiosis. Facing the lack of defined research strategy to...
Ultra long-lived plasma cells in the human small intestine produce microbiota-reactive IgA antibodies [0.03%]
人小肠中的超长寿命浆细胞产生反应微生物群的IgA抗体
N B Pati,B K Chung,K Holm et al.
N B Pati et al.
A large fraction of the intestinal microbiota is highly coated with secretory IgA, and bacteria-specific IgA is believed to shape the composition of the microbiota. A hallmark of the adaptive immune system is immunological memory to specifi...
Engraftment of staphylococcal strains on human skin can competitively displace native staphylococci [0.03%]
金黄色葡萄球菌的定植可竞争性替换人类皮肤上的固有菌群
C Feidenhansl,K Schweinshaut,E Rruci et al.
C Feidenhansl et al.
Topical probiotic formulations containing live bacteria are being explored as treatments for skin disorders such as atopic dermatitis and acne vulgaris. Certain bacterial strains with antimicrobial and/or anti-inflammatory properties show p...