Emerging, Uncommon, and Aggressive Pediatric Kidney Tumors: An Update and Diagnostic Pitfalls [0.03%]
儿童肾脏肿瘤的新兴类型、罕见类型及侵袭性类型：更新与诊断陷阱
Lauren N Parsons,Amy L Treece
Lauren N Parsons
Although favorable histology Wilms tumors are the most prevalent pediatric renal tumor, the remainder includes a small but diverse and important group of malignant neoplasms. Among these are diffuse anaplastic Wilms tumor, blastemal Wilms t...
Primary Central Nervous System Mesenchymal Neoplasms in the Pediatric Population-An Update [0.03%]
儿童群体中主要的中枢神经系统间质性肿瘤最新研究动态
Sanda Alexandrescu
Sanda Alexandrescu
This article reviews the latest updates in the classification and understanding of pediatric primary central nervous system mesenchymal tumors. It highlights changes in the World Health Organization Classification, including new tumor entit...
Sanda Alexandrescu
Sanda Alexandrescu
Recent strides in pediatric neuropathology have revolutionized the field. The integration of advanced technologies like next-generation sequencing and methylation arrays have refined the diagnosis and classifications of pediatric brain tumo...
Updates on Oncologic Genitourinary Pathology: Focus on Molecular Data and Biomarkers Relevant for Disease Classification and Clinical Management [0.03%]
泌尿生殖道肿瘤病理学进展：与疾病分类和临床处理相关的分子数据和生物标志物聚焦
Andrés Martin Acosta
Andrés Martin Acosta
Current Role of MicroRNAs in the Diagnosis and Clinical Management of Germ Cell Tumors [0.03%]
微小核糖核酸在生殖细胞肿瘤诊断和临床治疗中的作用
Nuno Tiago Tavares,Rui Henrique,Carmen Jerónimo et al.
Nuno Tiago Tavares et al.
Germ cell tumors (GCTs) are a rare and heterogeneous group of neoplasms arising from primitive germ cells. MicroRNAs are small noncoding RNAs that have emerged as potential cancer biomarkers in the last decade. In particular, miR-371a-3p ha...
Maurizio Colecchia,Michelangelo Fiorentino,Costantino Ricci et al.
Maurizio Colecchia et al.
This article reviews potential future changes in the classification of sex cord stromal tumors (SCST). The most useful immunohistochemical stains are summarized, and recent molecular developments are highlighted, considering their clinical ...
(Epi)genetic and Genomic Features of Pediatric and Adult Germ Cell Tumors [0.03%]
儿童和成人生殖细胞瘤的(表观)遗传和基因组特征
Alexander Fichtner,Stefanie Zschäbitz,Daniel Nettersheim et al.
Alexander Fichtner et al.
Testicular germ cell tumors (TGCTs) are a heterogeneous group of tumors that occur more commonly in adolescent and adult men. Depending on their age of onset, biological behavior, morphologic characteristics, and molecular alterations, they...
Updates on Urothelial Carcinoma of the Upper Urinary Tract with a Focus on Molecular Findings [0.03%]
聚焦分子发现的上尿路尿路上皮癌研究进展
Compérat Eva,Kläger Johannes,Shariat Shahrokh et al.
Compérat Eva et al.
Urothelial carcinoma (UC) of the upper urinary tract (UUT) is rare, constituting 5% to 10% of UCs, with a higher prevalence in males and older adults. It encompasses various subtypes and, unlike UC of the bladder, often presents as invasive...
Jie-Fu Chen,Hikmat Al-Ahmadie
Jie-Fu Chen
Urothelial carcinoma exhibits a wide spectrum of morphologic and molecular heterogeneity. Advances in molecular testing have improved our understanding of the molecular biology of urothelial carcinoma, including recurrent genomic alteration...
Deciphering Complexity: The Molecular Landscape of Castration-Resistant Prostate Cancer [0.03%]
破解复杂性：去势抵抗性前列腺癌的分子景观
Giuseppe Nicolò Fanelli,Pier Vitale Nuzzo,Filippo Pederzoli et al.
Giuseppe Nicolò Fanelli et al.
Despite improvements in diagnosis and treatment approaches, prostate cancer (PC) remains a leading cause of cancer-related death in men. PC progresses through various stages, mostly driven by androgen receptor signaling. However, after andr...