Evolving Controversies in Assessing Gastrointestinal Disorders: The Pathologist's Role [0.03%]
胃肠疾病评估中的争议与发展:病理学家的角色
Nicole C Panarelli
Nicole C Panarelli
The Diagnosis of Rare and Problematic Gastrointestinal Tract Infections: An Approach to a Road Less Traveled [0.03%]
罕见和棘手的胃肠道感染诊断:一条不寻常的道路的方法学探讨
Tomas Slavik
Tomas Slavik
The histopathologist is an integral part of the specialty team involved in the diagnosis of rare and problematic gastrointestinal tract infections. Frequently, routine hematoxylin and eosin morphology, supported by various histochemical and...
Byoung Uk Park,Fowsiyo Ahmed,Catherine E Hagen
Byoung Uk Park
Graft-versus-host disease (GVHD) continues to be a major cause of morbidity after allogeneic stem cell transplantation. This article summarizes current approaches to grading and reporting gastrointestinal GVHD while outlining key histopatho...
Histologic Activity in Inflammatory Bowel Disease:: Clinical Importance and Pathologic Evaluation [0.03%]
炎症性肠病的组织学活动度:临床意义和病理评估
Alexandros D Polydorides
Alexandros D Polydorides
Newer, more comprehensive treatment endpoints in the clinical management of patients with inflammatory bowel disease necessitate a robust, accurate, and reproducible approach during the histologic examination of disease activity in specimen...
Juan Putra,Jeffrey D Goldsmith
Juan Putra
The diagnosis of celiac disease requires integration of clinical features, serologic testing, and histopathologic findings. Duodenal biopsy remains essential, with characteristic findings that include villous atrophy, crypt hyperplasia, and...
The Intricacies of the Histopathology of Eosinophilic Esophagitis: A Critical Review [0.03%]
嗜酸细胞性食管炎活检病理特征的复杂性:一例批判性综述
Jose Jessurun,Justyna Szafranska,Lihui Qin
Jose Jessurun
Eosinophilic esophagitis is a chronic, immune-mediated disorder that afflicts both adults and children. Dysphagia and food impaction are common symptoms in adults, whereas children experience failure to thrive, vomiting, and food aversion. ...
Pathologic Assessment and Staging Cancers of Digestive Organs in the Era of Neoadjuvant Therapy [0.03%]
新辅助治疗时代的消化系统肿瘤病理评估和分期
Monika Vyas,Dipti M Karamchandani
Monika Vyas
Neoadjuvant therapy is employed to downstage many locally advanced gastrointestinal and pancreatic cancers, reduce tumor burden, and improve survival. However, treatment also produces gross and histologic therapy-related changes, confoundin...
Invasive Front and Peritumoral Prognostic Factors in Colorectal Cancer: Current Perspectives and Future Considerations [0.03%]
结直肠癌侵袭性前缘及瘤周预后因素的现状与未来考虑事项
Sameer Shivji,Rish K Pai,Richard Kirsch
Sameer Shivji
The invasive front and peritumoral region of colorectal cancers are replete with powerful prognostic biomarkers that can predict oncologic outcomes with far greater precision than achievable by tumor, node, metastasis (TNM) stage alone. Thi...
Mucinous Carcinomas of the Gastrointestinal and Gynecologic Tracts-Diagnostic Challenges in Overlapping Pathologies [0.03%]
胃肠和生殖道黏液癌-重叠病变的诊断难题
Mary Kinloch,David F Schaeffer
Mary Kinloch
Mucinous carcinomas of the gastrointestinal and gynecologic tracts constitute a biologically and morphologically heterogeneous group of epithelial malignancies defined by prominent extracellular mucin production. Accurate classification of ...
Common Sense Reporting of Colorectal Adenocarcinoma in Endoscopically Obtained Samples [0.03%]
内镜获得的标本中结直肠腺癌的合理报告事项
Domenika Ortiz Requena,Rhonda K Yantiss
Domenika Ortiz Requena
Some authors recommend including numerous histologic prognostic features when reporting colorectal carcinomas detected in endoscopic specimens. Unfortunately, data regarding their utility in polypectomy specimens (1) are mostly derived from...