Diagnostic Challenges and Recent Developments in Soft Tissue Pathology. Preface [0.03%]
软组织病理学的诊断挑战及 recent developments。前言
Leona A Doyle,Karen J Fritchie
Leona A Doyle
Advances in the Molecular Analysis of Soft Tissue Tumors and Clinical Implications [0.03%]
软组织肿瘤分子分析进展及临床意义
Adrian Marino-Enriquez
Adrian Marino-Enriquez
The emergence of high-throughput molecular technologies has accelerated the discovery of novel diagnostic, prognostic and predictive molecular markers. Clinical implementation of these technologies is expected to transform the practice of s...
Genetics of Gastrointestinal Stromal Tumors: A Heterogeneous Family of Tumors? [0.03%]
胃肠间质瘤的遗传学：一个异质性的肿瘤家族吗？
Deepa T Patil,Brian P Rubin
Deepa T Patil
Approximately 85-90% of adult gastrointestinal stromal tumors (GISTs) harbor KIT and PDGFRA mutations. The remaining cases, including the majority of pediatric GISTs, lack these mutations, and have been designated as KIT/PDGFRA wild-type (W...
Leona A Doyle
Leona A Doyle
A variety of different non-mesenchymal neoplasms may mimic sarcoma, in particular sarcomatoid carcinoma and melanoma, but also mesothelioma and rarely some lymphomas. This article reviews the key clinical and histologic features of such neo...
Nicole N Riddle,Jerad M Gardner
Nicole N Riddle
Soft tissue pathology is a rapidly changing subspecialty. New entities are described relatively often, and new molecular findings for soft tissue tumors are reported in the literature almost every month. This article summarizes the major fe...
Vickie Y Jo
Vickie Y Jo
Primary myoepithelial neoplasms of soft tissue are uncommon, and have been increasingly characterized by clinicopathologic and genetic means. Tumors are classified as mixed tumor/chondroid syringoma, myoepithelioma, and myoepithelial carcin...
Soo-Jin Cho,Andrew Horvai
Soo-Jin Cho
Soft tissue lesions can contain bone or cartilage matrix as an incidental, often metaplastic, phenomenon or as a diagnostic feature. The latter category includes a diverse group ranging from self-limited proliferations to benign neoplasms t...
Alyaa Al-Ibraheemi,Harry Kozakewich,Antonio R Perez-Atayde
Alyaa Al-Ibraheemi
Many benign and malignant soft tissue tumors in children are challenging and their diagnosis requires knowledge of their vast diversity, histopathological complexity, and immunohistochemical, cytogenetic, and molecular characteristics. The ...
Karen J Fritchie
Karen J Fritchie
A variety of benign and malignant retroperitoneal mesenchymal lesions may have a component of adipose tissue, including entities such as lipoma, myolipoma, angiomyolipoma, solitary fibrous tumor, genital stromal tumors, and well-differentia...
Inga-Marie Schaefer,Christopher D M Fletcher
Inga-Marie Schaefer
The diagnostic spectrum of spindle cell neoplasms arising in the retroperitoneum is wide and, in the presence of commonly shared morphologic features, it may be challenging to establish a correct diagnosis in certain cases. Beyond seemingly...