Brandon Bernard,Christopher J Sweeney
Brandon Bernard
Testicular germ cell tumors (GCTs) include seminoma and nonseminoma. Chance of cure is excellent for clinical stage I disease regardless of whether adjuvant treatment or a surveillance strategy with treatment only for those who relapse is u...
Brooke E Howitt,Daniel M Berney
Brooke E Howitt
This article reviews the most frequently encountered tumor of the testis; pure and mixed malignant testicular germ cell tumors (TGCT), with emphasis on adult (postpubertal) TGCTs and their differential diagnoses. We additionally review TGCT...
Lauren C Harshman,Mark A Preston,Joaquim Bellmunt et al.
Lauren C Harshman et al.
In 2014, more than 74,000 new cases and 15,000 deaths from bladder cancer were estimated to occur. The most reliable prognostic factors for survival are pathologic stage and histologic grade. Accordingly, a good understanding of the patholo...
James P Solomon,Donna E Hansel
James P Solomon
Bladder cancer is the fourth most common cancer in men, and is associated with significant morbidity and mortality. Pathologic evaluation of urothelial cancers relies predominantly on histomorphologic features but can be aided in a small su...
Laurence Albiges,André P Fay,Rana R McKay et al.
Laurence Albiges et al.
Renal cell carcinoma (RCC) is a heterogeneous disease. A rigorous diagnostic assessment by a pathologist with close communication with the clinician provides more accurate prognostication and informed treatment decisions. In the localized s...
Rohit Mehra,Steven C Smith,Mukul Divatia et al.
Rohit Mehra et al.
This article reviews emerging entities in renal epithelial neoplasia, including tubulocystic carcinoma, clear-cell-papillary renal cell carcinoma (RCC), thyroid-like follicular RCC, ALK-related RCC, translocation RCC, acquired cystic diseas...
Adult Renal Cell Carcinoma: A Review of Established Entities from Morphology to Molecular Genetics [0.03%]
成人肾细胞癌：从形态学到分子遗传学的既定实体回顾
Michelle S Hirsch,Sabina Signoretti,Paola Dal Cin
Michelle S Hirsch
According to the current World Health Organization (WHO), renal cell carcinomas (RCCs) that primarily affect adults are classified into 8 major subtypes. Additional emerging entities in renal neoplasia have also been recently recognized and...
Active Surveillance: Pathologic and Clinical Variables Associated with Outcome [0.03%]
活性监测：与结果相关的病理和临床变量
Mark Pomerantz
Mark Pomerantz
Over the past 10 years, active surveillance has emerged as a primary management option for men diagnosed with low-risk prostate cancer. Given the morbidity associated with curative treatment, active surveillance maintains quality of life fo...
George J Netto
George J Netto
A wide array of molecular markers and genomic signatures, reviewed in this article, may soon be used as adjuncts to currently established screening strategies, prognostic parameters, and early detection markers. Markers of genetic susceptib...
Adebowale J Adeniran,Peter A Humphrey
Adebowale J Adeniran
In the past several years, modifications have been made to the original Gleason system with resultant therapeutic and prognostic implications. Several morphologic variants of prostatic adenocarcinoma have also been described. Prostate patho...