J N Rosenbaum,Ricardo Vincent Lloyd
J N Rosenbaum
Pancreatic neuroendocrine neoplasms (Pan-NENs) are rare but clinically important lesions. Pan-NENs are known for and often categorized by their capacity to produce clinical syndromes mediated by the production of hormones. Despite sometimes...
Paragangliomas Arising in the Head and Neck: A Morphologic Review and Genetic Update [0.03%]
头颈部副神经节瘤的形态学复习和遗传学新进展
Michelle D Williams,Thereasa A Rich
Michelle D Williams
Seventy percent of parasympathetic paragangliomas arise in the head and neck and are nonsecretory. Awareness of the differential diagnosis based on location, overlapping morphology, and immunohistochemical profiles aids in the correct diagn...
Isobel C Mouat,Thomas J Giordano
Isobel C Mouat
Pathologists are highly skilled at the evaluation of adrenal neoplasms. Occasional adrenocortical tumors can be diagnostically challenging and supplementary tools can assist in these cases. Histologic and molecular studies support a model t...
Virginia A LiVolsi,Kathleen T Montone,Zubair N Baloch
Virginia A LiVolsi
This review focuses on the pathologic entities associated with hyperparathyroidism in humans. A discussion of the lesions, their embryology, and pathologic features is included. Immunohistology, cytopathology, and a brief overview of molecu...
Marc P Pusztaszeri,William C Faquin,Peter M Sadow
Marc P Pusztaszeri
The complex interactions between immune cells and tumor cells in cancer play a major role in tumor development and subsequent patient outcomes. Different types of tumor-associated inflammatory cells (TAICs), such as dendritic cells, macroph...
Guido Fadda,Esther Diana Rossi
Guido Fadda
Recent insight into the molecular mechanisms of thyroid carcinogenesis has led to studies involving newly directed antibodies. With the introduction of new molecular targeted therapies, these antibodies may represent useful predictors of th...
Namrata Setia,Justine A Barletta
Namrata Setia
Poorly differentiated thyroid carcinoma (PDTC) has been recognized for the past 30 years as an entity showing intermediate differentiation and clinical behavior between well-differentiated thyroid carcinomas (ie, papillary thyroid carcinoma...
Anthony Chang
Anthony Chang
Emerging Concepts and Controversies in Renal Pathology: C4d-Negative and Arterial Lesions as Manifestations of Antibody-Mediated Transplant Rejection [0.03%]
肾脏病理学中的新兴概念和争议：C4d阴性以及抗体介导的移植排斥反应的动脉病变
Mark Haas
Mark Haas
The consensus classification of antibody-mediated rejection (AMR) of renal allografts developed at the Sixth Banff Conference on Allograft Pathology, in 2001, identified three findings necessary for the diagnosis of active AMR: histologic e...
Michael Mengel
Michael Mengel
In this article, various omics technologies and their applications in renal pathology (native and transplant biopsies) are reviewed and discussed. Despite significant progress and novel insights derived from these applications, extensive ad...