Sanda Alexandrescu
Sanda Alexandrescu
Recent strides in pediatric neuropathology have revolutionized the field. The integration of advanced technologies like next-generation sequencing and methylation arrays have refined the diagnosis and classifications of pediatric brain tumo...
Updates on Oncologic Genitourinary Pathology: Focus on Molecular Data and Biomarkers Relevant for Disease Classification and Clinical Management [0.03%]
泌尿生殖道肿瘤病理学进展:与疾病分类和临床处理相关的分子数据和生物标志物聚焦
Andrés Martin Acosta
Andrés Martin Acosta
Current Role of MicroRNAs in the Diagnosis and Clinical Management of Germ Cell Tumors [0.03%]
微小核糖核酸在生殖细胞肿瘤诊断和临床治疗中的作用
Nuno Tiago Tavares,Rui Henrique,Carmen Jerónimo et al.
Nuno Tiago Tavares et al.
Germ cell tumors (GCTs) are a rare and heterogeneous group of neoplasms arising from primitive germ cells. MicroRNAs are small noncoding RNAs that have emerged as potential cancer biomarkers in the last decade. In particular, miR-371a-3p ha...
Maurizio Colecchia,Michelangelo Fiorentino,Costantino Ricci et al.
Maurizio Colecchia et al.
This article reviews potential future changes in the classification of sex cord stromal tumors (SCST). The most useful immunohistochemical stains are summarized, and recent molecular developments are highlighted, considering their clinical ...
(Epi)genetic and Genomic Features of Pediatric and Adult Germ Cell Tumors [0.03%]
儿童和成人生殖细胞瘤的(表观)遗传和基因组特征
Alexander Fichtner,Stefanie Zschäbitz,Daniel Nettersheim et al.
Alexander Fichtner et al.
Testicular germ cell tumors (TGCTs) are a heterogeneous group of tumors that occur more commonly in adolescent and adult men. Depending on their age of onset, biological behavior, morphologic characteristics, and molecular alterations, they...
Updates on Urothelial Carcinoma of the Upper Urinary Tract with a Focus on Molecular Findings [0.03%]
聚焦分子发现的上尿路尿路上皮癌研究进展
Compérat Eva,Kläger Johannes,Shariat Shahrokh et al.
Compérat Eva et al.
Urothelial carcinoma (UC) of the upper urinary tract (UUT) is rare, constituting 5% to 10% of UCs, with a higher prevalence in males and older adults. It encompasses various subtypes and, unlike UC of the bladder, often presents as invasive...
Jie-Fu Chen,Hikmat Al-Ahmadie
Jie-Fu Chen
Urothelial carcinoma exhibits a wide spectrum of morphologic and molecular heterogeneity. Advances in molecular testing have improved our understanding of the molecular biology of urothelial carcinoma, including recurrent genomic alteration...
Deciphering Complexity: The Molecular Landscape of Castration-Resistant Prostate Cancer [0.03%]
破解复杂性:去势抵抗性前列腺癌的分子景观
Giuseppe Nicolò Fanelli,Pier Vitale Nuzzo,Filippo Pederzoli et al.
Giuseppe Nicolò Fanelli et al.
Despite improvements in diagnosis and treatment approaches, prostate cancer (PC) remains a leading cause of cancer-related death in men. PC progresses through various stages, mostly driven by androgen receptor signaling. However, after andr...
Mesenchymal Neoplasms of the Bladder and Male Genital Tract, including the Perineum and Scrotum [0.03%]
包括会阴和阴囊的膀胱和男性生殖道间叶源性肿瘤
David J Papke Jr
David J Papke Jr
Mesenchymal neoplasms of the bladder and male genital tract are uncommonly encountered in routine diagnostic practice and present diagnostic challenges. Here, I systematically survey mesenchymal tumors at each body site, including the sperm...
David J Papke Jr
David J Papke Jr
Mesenchymal neoplasms of the kidney present challenges because they are uncommon, and because perinephric soft tissue biopsies are sometimes submitted as "kidney" masses, causing diagnostic confusion. Here, the author thoroughly reviews mes...