Congenital Cystic Lung Lesions: An Update on Clinical and Pathologic Correlates [0.03%]
先天性肺囊肿病变：临床和病理对照的最新研究进展
Nya D Nelson,Jennifer Pogoriler
Nya D Nelson
"Cystic" lung lesions that arise in utero or early postnatal life encompass congenital pulmonary airway malformations, sequestrations, pleuropulmonary blastoma, and bronchogenic cyst, but this category also includes noncystic lesions such a...
Pediatric Liver Transplant Pathology: An Update and Practical Consideration [0.03%]
儿科肝脏移植病理：更新与实用考量
Ameet I Thaker,Juan Putra
Ameet I Thaker
This review provides a summary of the diagnostic approach to pediatric liver transplantation (LT) pathology. It emphasizes the pathologic features of T-cell-mediated rejection, the most common finding on liver allograft biopsies, and discus...
Cancer Predisposition Syndromes Associated with Most Common Pediatric Solid Tumors [0.03%]
儿童常见实体瘤相关的癌症易感综合征
Jennifer C Scull,Dolores Lopez-Terrada
Jennifer C Scull
In the pediatric setting, cancer predisposition syndromes account for about 8% to 20% of all cancer diagnoses, and these numbers can be higher depending on the tumor type. In this study, we describe a selection of the most common cancer pre...
Pediatric Pathology: Emerging Entities, Current Trends, and Comprehensive Updates, "Histiocytosis" [0.03%]
儿科病理学：新兴实体、当前趋势和全面更新，“组织细胞增生症”
Maria Laura Galluzzo Mutti,Jennifer Picarsic
Maria Laura Galluzzo Mutti
Histiocytic lesions, now classified as a myeloid-derived neoplasia, consist of mutated monocyte-derived dendritic and macrophage cells infiltrating tissues. They are primarily driven by kinase-activating alterations in mitogen-activated pro...
Jason Jarzembowski
Jason Jarzembowski
Peripheral neuroblastic tumors consist of a variety of neoplasms ranging from benign to highly malignant, with significant intertumoral and intratumoral heterogeneity. The current gold standard in classification, the International Neuroblas...
Catherine K Gestrich,Alyaa Al-Ibraheemi
Catherine K Gestrich
Receptor tyrosine kinases (RTKs) are crucial cell surface receptors that activate intracellular signaling pathways in response to external stimuli, regulating cell proliferation and survival. Under normal conditions, RTK activity is tightly...
Ashlie E Rubrecht,Archana Shenoy
Ashlie E Rubrecht
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, representing approximately 40% of all pediatric soft tissue sarcomas and 3% of all pediatric cancers. RMSs are a heterogeneous group of neoplasms with variations in ...
Iván A González,Maria C Pacheco
Iván A González
The goal of this review is to provide a practical update on hepatic lesions affecting the pediatric population and is not meant to be an exhaustive summary of each entity. Hepatoblastoma is purposely not discussed as recent comprehensive re...
Emerging, Uncommon, and Aggressive Pediatric Kidney Tumors: An Update and Diagnostic Pitfalls [0.03%]
儿童肾脏肿瘤的新兴类型、罕见类型及侵袭性类型：更新与诊断陷阱
Lauren N Parsons,Amy L Treece
Lauren N Parsons
Although favorable histology Wilms tumors are the most prevalent pediatric renal tumor, the remainder includes a small but diverse and important group of malignant neoplasms. Among these are diffuse anaplastic Wilms tumor, blastemal Wilms t...
Primary Central Nervous System Mesenchymal Neoplasms in the Pediatric Population-An Update [0.03%]
儿童群体中主要的中枢神经系统间质性肿瘤最新研究动态
Sanda Alexandrescu
Sanda Alexandrescu
This article reviews the latest updates in the classification and understanding of pediatric primary central nervous system mesenchymal tumors. It highlights changes in the World Health Organization Classification, including new tumor entit...