Jeffrey M Cloutier,Darcy A Kerr
Jeffrey M Cloutier
GLI1-altered mesenchymal tumors comprise an emerging group of neoplasms characterized by fusions or amplifications involving GLI1, a gene that encodes a key regulator of the Hedgehog signaling pathway. In recent years, tumors with GLI1 alte...
Laura M Warmke,Wendong Yu,Jeanne M Meis
Laura M Warmke
Sclerosing epithelioid fibrosarcoma (SEF) is a distinctive sarcoma that may arise in nearly any soft tissue site or bone. While there has been past controversy as to whether it is related to low-grade fibromyxoid sarcoma (LGFMS), it has bee...
Phoebe M Hammer,Serena Y Tan
Phoebe M Hammer
Perivascular epithelioid cell tumors (PEComas) are a heterogenous group of mesenchymal neoplasms with a mixed myomelanocytic immunophenotype. PEComa-family tumors include angiomyolipoma, lymphangioleiomyomatosis, and a large category of rar...
Raul Perret,Isabelle Hostein
Raul Perret
Superficial CD34-positive fibroblastic tumor is a mesenchymal neoplasm of "intermediate malignancy" recently included in the fifth edition of the World Health Organization classification of soft tissue and bone tumors. In this review, we su...
What's Coming Down the Tube: Current and Emerging Topics in Gastrointestinal Pathology [0.03%]
胃肠病理学当前及发展前景：热点话题
Rondell P Graham
Rondell P Graham
Infectious Disease Pathology of the Gastrointestinal Tract: Diagnosing the Challenging Cases [0.03%]
胃肠病原病理学：诊断疑难病症
Laura W Lamps
Laura W Lamps
Infectious diseases of the GI tract mimic a variety of other GI diseases, including chronic idiopathic inflammatory bowel disease and ischemia. It can be challenging to identify pathogens in tissue sections as well, as many trainees are not...
A Practical Approach to Small Round Cell Tumors Involving the Gastrointestinal Tract and Abdomen [0.03%]
胃肠道和腹部小圆细胞肿瘤的诊断与鉴别诊断
Khin Thway,Cyril Fisher
Khin Thway
Small round cell neoplasms are diagnostically challenging owing to their clinical and pathologic overlap, necessitating use of large immunopanels and molecular analysis. Ewing sarcomas (ES) are the most common, but EWSR1 is translocated in ...
Nicole C Panarelli
Nicole C Panarelli
Pathologists are increasingly asked to evaluate mast cell infiltrates in the gastrointestinal tract when there is clinical concern for systemic mastocytosis or a variety of functional disorders, including irritable bowel syndrome and mast c...
Gastrointestinal Biopsies in the Patient Post-Stem Cell Transplant: An Approach to Diagnosis [0.03%]
移植后患者的胃肠道活检：诊断方法
Tao Zhang,Catherine E Hagen
Tao Zhang
Graft-versus-host disease (GVHD) is a major complication of hematopoietic stem cell transplantation (SCT), leading to a significant morbidity and mortality. Histologically, gastrointestinal GVHD is characterized by crypt apoptosis and dropo...
Alisha D Ware,Laura M Wake,Yuri Fedoriw
Alisha D Ware
Lymphoproliferative disorders are a heterogeneous group of neoplasms with varying clinical, morphologic, immunophenotypic, and genetic characteristics. A subset of lymphomas have a proclivity for the gastrointestinal tract, although this re...