James E Denney,Lee Bentley Syler,Emily F Mason
James E Denney
Hematologic malignancies are one of the more common neoplasms to occur in the sinonasal tract and include a wide range of entities, including mature and immature B cell and T cell neoplasms as well as plasma cell dyscrasias and histiocytic ...
Alex N Perez,Carlos N Prieto Granada
Alex N Perez
The spindle cell neoplasms include sinonasal tract angiofibroma (STA), glomangiopericytoma (GPC), and biphenotypic sinonasal sarcoma (BSNS). These entities share some clinical, histomorphologic, immunohistochemical, and even molecular chara...
Ruth K Foreman,Lyn M Duncan
Ruth K Foreman
Sinonasal mucosal melanoma (SNMM) is a rare aggressive tumor often diagnosed at advanced stage. SNMM is associated with a greater than 50% rate of recurrence and a disease-specific 5 year survival rate of less than 25%. Sinonasal anatomy ma...
Giorgia Arcovito,Alessandro Franchi
Giorgia Arcovito
Among sinonasal malignancies, adenocarcinomas account for the second most common entity after squamous cell carcinoma. They span a wide spectrum of neoplasms with heterogeneous features including intestinal-type adenocarcinoma (ITAC), non-i...
Michael W Mikula,Lisa M Rooper
Michael W Mikula
In the sinonasal tract, two tumor types are defined by neuroectodermal differentiation. Olfactory neuroblastoma (ONB), the traditional member of this category, is a keratin-negative neuroectodermal neoplasm that has lobulated architecture a...
Sinonasal Undifferentiated and Poorly Differentiated Carcinomas: An Update [0.03%]
鼻窦未分化及分化差的癌：最新研究进展
Arshi Tandon,Aanchal Kakkar
Arshi Tandon
Recent advances have increased our understanding of sinonasal undifferentiated and poorly differentiated carcinomas (UD/PDca). Several novel molecularly defined entities have emerged from within this group. Notably, they have histologic fea...
Human Papillomavirus in Sinonasal Tract Tumors-Another Head and Neck "Hot Spot" for Prognostically Favorable Viral Disease [0.03%]
人乳头瘤病毒在鼻窦肿瘤中的作用-另一种预后良好的病毒感染的头颈部“热点”区域
James S Lewis Jr
James S Lewis Jr
The sinonasal tract, while an uncommon site of SCC overall, is another "hot spot" for transcriptionally-active high-risk HPV-associated tumors. The accumulating data show that, across the world, the rate of HPV-associated SCC here is approx...
DEK::AFF2 Carcinoma of the Sinonasal Tract and Skull Base: A Comprehensive Review [0.03%]
鼻窦和颅底腺样囊性癌(DEK::AFF2)的综合述评
Jonathan P Rivera,Ying-Ju Kuo,Jen-Fan Hang
Jonathan P Rivera
DEK::AFF2 carcinoma is an emerging entity of the sinonasal tract and skull base, commonly exhibiting exophytic and endophytic papillary growth, complex anastomosing trabeculae, monotonous cytomorphology, acantholytic change, and tumor-infil...
Sinonasal Hamartomas [0.03%]
鼻窦黏液囊肿
Elan Hahn,Ilan Weinreb
Elan Hahn
A variety of hamartomatous lesions have been described in the sinonasal tract. These include respiratory epithelial adenomatoid hamartoma (REAH), seromucinous hamartoma (SH), and nasal chondromesenchymal hamartoma (NCMH). REAH and SH, demon...
William R Perry,Aaron M Udager
William R Perry
Sinonasal papillomas are a group of uncommon benign neoplasms that often represent a diagnostic challenge for surgical pathologists due to their diverse morphologic features. Our understanding of the molecular pathogenesis of these tumors h...