Empirical Vancomycin Dosing in Pediatric Patients with Congenital Heart Disease and the Impact of Cardiopulmonary Bypass on Trough Concentrations [0.03%]
先天性心脏病患儿万古霉素的临床用药及体外循环对谷浓度的影响
Christopher A Thomas,Amy Picone,Sharad Menon et al.
Christopher A Thomas et al.
Objectives: To determine the optimal vancomycin dosing regimen to achieve empirical goal trough concentrations in pediatric patients with congenital heart disease and to examine the impact of cardiopulmonary bypass on van...
Evaluation of Progesterone Utilization and Birth Outcomes in a State Medicaid Plan [0.03%]
评估州级医疗补助计划中的黄体酮使用情况及分娩结果
Tasmina Hydery,Mylissa K Price,Bonnie C Greenwood et al.
Tasmina Hydery et al.
Objectives: Progesterone (hydroxyprogesterone caproate injection and vaginal progesterone) has been shown to reduce preterm birth (PTB) rates by a third among pregnant women at high risk. The purpose of this analysis is t...
Prothrombin Complex Concentrate Reduces Blood Product Utilization in Heart Transplantation [0.03%]
prothrombin复合物浓缩剂可减少心脏移植中的血液制品使用
Daniel H Enter,Anthony L Zaki,Megan Marsh et al.
Daniel H Enter et al.
Background: Current practices for the reversal of warfarin before cardiac surgery include the use of vitamin K and fresh frozen plasma (FFP) to reduce the risk of bleeding. Although the 2010 International Society of Heart...
Assessment of an Extended Interval Fondaparinux Dosing Regimen for Venous Thromboembolism Prophylaxis in Critically Ill Patients with Severe Renal Dysfunction Using Antifactor Xa Levels [0.03%]
采用抗因子Xa水平评估延长间隔给药的 fondaparinux方案用于严重肾功能不全重症患者静脉血栓预防的效果
Krista A Wahby,Lauren K Riley,Steven D Tennenberg
Krista A Wahby
Objective: Pharmacologic options for venous thromboembolism (VTE) prophylaxis are often limited in critically ill patients due to thrombocytopenia and multisystem organ dysfunction. Fondaparinux offers potential advantage...
Multicenter Study
Pharmacotherapy. 2017 Oct;37(10):1241-1248. DOI:10.1002/phar.2014 2017
Repurposing Valproate, Enteral Clonidine, and Phenobarbital for Comfort in Adult ICU Patients: A Literature Review with Practical Considerations [0.03%]
再利用 valproate、肠内氯硝西泮和苯巴比妥用于成人ICU患者的舒适护理：带有实际考虑的文献综述
David J Gagnon,Gabriel V Fontaine,Richard R Riker et al.
David J Gagnon et al.
Provision of adequate sedation is a fundamental part of caring for critically ill patients. Propofol, dexmedetomidine, and benzodiazepines are the most commonly administered sedative medications for adult patients in the intensive care unit...
Contemporary Time Trends in Use of Antiplatelet Agents Among Patients with Acute Coronary Syndrome and Comorbid Diabetes Mellitus or Chronic Kidney Disease [0.03%]
急性冠脉综合征合并糖尿病或慢性肾脏病患者的抗血小板药物应用趋势分析
Rishi J Desai,Julia Spoendlin,Helen Mogun et al.
Rishi J Desai et al.
Study objective: To describe contemporary trends of P2Y12 inhibitor use in patients with acute coronary syndrome (ACS) and comorbid diabetes mellitus (DM) and/or chronic kidney disease (CKD) who have a higher risk of recu...
Pharmacotherapeutic Management of Gastrointestinal Bleeding in Patients with Continuous-Flow Left Ventricular Assist Devices [0.03%]
左心室辅助装置植入患者的消化道出血的药物管理
Adam C Sieg,Jeremy D Moretz,Edward Horn et al.
Adam C Sieg et al.
Continuous-flow left ventricular assist devices (CF-LVADs) have become an integral component of the management in patients with advanced heart failure, serving as destination therapy or as a bridge to heart transplantation. Despite signific...
G Caleb Alexander,Jeromie Ballreich,Mariana P Socal et al.
G Caleb Alexander et al.
The high prices of specialty pharmaceuticals are causing some public programs to ration care and many private insurers, including Medicare drug plans, to place specialty drugs on high cost-sharing tiers. As a result, access to these drugs i...
The Emergence of Second-Generation Lethal Injection Protocols: A Brief History and Review [0.03%]
第二代致死注射用药方案的出现：简史及述评
Daniel R Malcom,Frank Romanelli
Daniel R Malcom
The history of capital punishment in the United States is long and controversial. In many cases, lethal injection has brought medical personnel, ethically and professionally charged with preserving life, into the arena of assisting the stat...
Factors in Variability of Serial Gabapentin Concentrations in Elderly Patients with Epilepsy [0.03%]
影响老年人癫痫患者加巴喷丁血药浓度波动的因素分析
Jeannine M Conway,Lynn E Eberly,Joseph F Collins et al.
Jeannine M Conway et al.
Objectives: To characterize and quantify the variability of serial gabapentin concentrations in elderly patients with epilepsy. Methods: ...