Pharmaceutical Considerations for Oncology Risk, Screening, and Drug Dosing in the Transgender Population [0.03%]
Amy Broadwater,Kevin N Astle
Amy Broadwater
Transgender individuals make up a significant portion of the United States population, yet little data are available regarding oncologic considerations for this population. Transgender individuals may utilize gender-affirming hormone therap...
Outcomes of CDK4/6 Inhibitor-Based Therapy in Premenopausal HR+/HER2- Metastatic Breast Cancer: Real World Data From A Multicenter Study [0.03%]
Hatice Odabaş,Omar Alomari,Seval Orman et al.
Hatice Odabaş et al.
Background: Breast cancer is the leading cause of cancer-related death in women worldwide. Hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) metastatic breast cancer (MBC) represents ...
Comparative Study
Pharmacotherapy. 2026 Apr;46(4):e70134. DOI:10.1002/phar.70134 2026
A Systematic Review of Clinically Significant Drug-Drug Interactions With Phenobarbital and Primidone [0.03%]
苯巴比妥和普瑞巴林临床显著的药物相互作用系统评价研究
Kyrellos Ghattas,Ji Tong Liu,Pansy Elsamadisi et al.
Kyrellos Ghattas et al.
Phenobarbital (PB) is historically used for management of seizure disorders but more recently has emerged as a prominent option for the management of alcohol withdrawal syndrome given data suggesting its benefit over benzodiazepines. An imp...
Cameron J McKinzie,Charissa W Kam,Paul M Beringer et al.
Cameron J McKinzie et al.
The advent of cystic fibrosis transmembrane conductance regulator (CFTR) modulators has dramatically changed the landscape of the clinical care of people with cystic fibrosis (PwCF). In particular, highly effective modulator therapy (HEMT) ...
DILIConsult: A Multi-Agent Large Language Model Framework for Evaluating Drug-Induced Liver Injury in ICU Settings [0.03%]
DILIConsult：一种用于评估重症监护环境中药物性肝损伤的多智能体大型语言模型框架
Alfred Zheng Ting Ho,Jeren Zheng Feng Law,Aiwen Wang et al.
Alfred Zheng Ting Ho et al.
Background: Large language models (LLMs) can support clinical decision-making by parsing databases and extracting relevant information. However, evaluating drug-induced liver injury (DILI) often requires processing length...
Comprehensive Review of Candidozyma (Candida) auris Management: Insights From the Society of Infectious Diseases Pharmacists [0.03%]
来自药物研究感染病学会的综合评论：管理 candidozyma (candida)auris 的见解
Caleb E Rux,Melissa D Johnson,Victoria C Grant et al.
Caleb E Rux et al.
Candidozyma (Candida) auris has emerged over the past two decades as a formidable global health threat due to its multidrug resistance, persistence in healthcare environments, and rapid nosocomial spread. Recently reclassified into the genu...
Response to "Comment on C-Reactive Protein and Neutrophil-to-Lymphocyte Ratio: Can They Be Used Interchangeably in Tracking Clozapine-Related Inflammation?" [0.03%]
C-反应蛋白与中性粒细胞/淋巴细胞比值：能否互换用于追踪氯氮平相关炎症？——回复评论文章
Nicoline Bihelek,Chad A Bousman,William G Honer et al.
Nicoline Bihelek et al.
Real-World Cardiovascular Outcomes of GLP-1 Receptor Agonists in Women With Type 2 Diabetes and Breast Cancer [0.03%]
GLP-1受体激动剂治疗2型糖尿病伴乳腺癌女性患者的真实世界心血管结局
Cyrille K Cornelio,Kevin Cowart,Janelle Perkins et al.
Cyrille K Cornelio et al.
Introduction: The cardiovascular (CV) benefits of glucagon-like-peptide-1 receptor agonist (GLP-1 RA) therapies are not well-established in women with breast cancer and type 2 diabetes (T2D). ...
Models Integrating Disease Heterogeneity and MPA Exposure Predict Systemic and Renal Efficacy of Mycophenolate in Pediatric Lupus Nephritis [0.03%]
整合疾病异质性和MPA暴露的模型预测了麦考酚酸酯在儿童狼疮性肾炎中的全身和肾脏疗效
Baojing Liu,Lizhi Chen,Jingxuan Lin et al.
Baojing Liu et al.
Objectives: This study aimed to develop and validate integrated prediction models for pediatric lupus nephritis (LN) treated with a mycophenolate mofetil (MMF)-based induction regimen (combined with glucocorticoids and hy...
Effectiveness of Stimulant Treatment in Preventing Fractures and Head Injuries in Patients With Narcolepsy: A Self-Controlled Case Series Study [0.03%]
多睡症患者使用刺激药物预防骨折和头部损伤的疗效：病例系列研究
Yunlong Zheng,Toshiki Fukasawa,Soichiro Masuda et al.
Yunlong Zheng et al.
Background: Previous cohort studies have investigated whether stimulants reduce injury risk in narcolepsy, but they faced potential biases such as confounding by indication and immortal time bias. We conducted a self-cont...