What Is Old Is New Again: Delafloxacin, a Modern Fluoroquinolone [0.03%]
老药新用：(delafloxacin，现代氟喹诺酮类药物)
Jonathan C Cho,Matthew P Crotty,Bryan P White et al.
Jonathan C Cho et al.
Delafloxacin is a new fluoroquinolone antimicrobial approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) in adults using dosage regimens of 300 mg intravenously every 12 hours, 450 mg orally every 12 ho...
Observational Comparative Effectiveness of Pharmaceutical Treatments for Obesity within the Veterans Health Administration [0.03%]
退伍军人健康管理局内药物治疗肥胖的观察比较效果研究
Ted R Grabarczyk
Ted R Grabarczyk
Study objective: To compare the effectiveness of weight-management medications used to assist with weight loss in real-world clinical practice in the Veterans Health Administration (VHA). ...
Comparative Study
Pharmacotherapy. 2018 Jan;38(1):19-28. DOI:10.1002/phar.2048 2018
Fidaxomicin versus Vancomycin as a First-Line Treatment for Clostridium difficile-Associated Diarrhea in Specific Patient Populations: A Pharmacoeconomic Evaluation [0.03%]
fidaxomicin与万古霉素作为特定人群首次治疗难辨梭菌相关性腹泻的药物经济学评估
Kelly R Reveles,Jennifer L Backo,Frank A Corvino et al.
Kelly R Reveles et al.
Objectives: The reduction in recurrent Clostridium difficile-associated diarrhea (CDAD) with fidaxomicin therapy may reduce hospital readmissions and lead to lower overall CDAD costs. However, studies assessing the cost-e...
Comparative Study
Pharmacotherapy. 2017 Dec;37(12):1489-1497. DOI:10.1002/phar.2049 2017
Impact of Insulin Detemir Administration Time on Hypoglycemia Rates in Hospitalized Patients [0.03%]
住院患者注射胰岛素类似物来得时时间对低血糖发生率的影响
Jennifer L Grelle,Sydney N Kutter,Megan E Giruzzi et al.
Jennifer L Grelle et al.
Study objective: To determine if insulin detemir administration time affects the frequency of hypoglycemia (blood glucose level
Comparison of Treatment Persistence with Dabigatran or Rivaroxaban versus Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation Patients: A Competing Risk Analysis in the French National Health Care Databases [0.03%]
法国国家健康保健数据库中房颤患者接受达比加群或利伐沙班与维生素K拮抗剂口服抗凝药治疗依从性的对比分析：竞争风险模型分析
Géric Maura,Cécile Billionnet,François Alla et al.
Géric Maura et al.
Background: Direct oral anticoagulants (DOACs) have been proposed as a more convenient alternative to vitamin K antagonists (VKAs), which are commonly associated with poor treatment persistence in non-valvular atrial fibr...
Comparative Study
Pharmacotherapy. 2018 Jan;38(1):6-18. DOI:10.1002/phar.2046 2018
Comparison of Weight-Based Dosing Strategies for Intravenous Immunoglobulin in Patients with Hematologic Malignancies [0.03%]
血液系统恶性肿瘤患者静脉注射免疫球蛋白的体重为基础的给药策略比较研究
Sarah E Stump,Allison J Schepers,Alexis R Jones et al.
Sarah E Stump et al.
Study objective: Intravenous immunoglobulin (IVIG) is a weight-based therapy used to treat and prevent infections in patients with hematologic malignancies. IVIG doses were calculated traditionally using actual body weigh...
Comparative Study
Pharmacotherapy. 2017 Dec;37(12):1530-1536. DOI:10.1002/phar.2047 2017
A Pharmacist-Led Program to Evaluate and Reduce Polypharmacy and Potentially Inappropriate Prescribing in Older HIV-Positive Patients [0.03%]
老年HIV阳性患者的药师主导的用药评估及减药和潜在不适宜处方干预项目
Ian R McNicholl,Monica Gandhi,C Bradley Hare et al.
Ian R McNicholl et al.
Objective: The goal of this pharmacist-led study was to utilize two validated instruments, Beers Criteria and Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP), to assess potentially inappro...
Randomized Controlled Trial
Pharmacotherapy. 2017 Dec;37(12):1498-1506. DOI:10.1002/phar.2043 2017
Evaluation and Treatment of Acute and Subacute Hearing Loss: A Review of Pharmacotherapy [0.03%]
急性及亚急性听力损失的药理治疗评估与治疗综述
Maryam T Fazel,Patrick M Jedlowski,Robert B Cravens Jr et al.
Maryam T Fazel et al.
Among various forms of hearing loss, there are acute (within 72 hrs) or subacute (weeks to months) presentations that may be reversible with early pharmacological intervention. The workup of a patient presenting with hypoacusia includes the...
Impact of Ketamine Use on Adjunctive Analgesic and Sedative Medications in Critically Ill Trauma Patients [0.03%]
氯胺酮使用对重症创伤患者辅助镇痛和镇静药物的影响
Kaitlin A Pruskowski,Kelly Harbourt,Mehrnaz Pajoumand et al.
Kaitlin A Pruskowski et al.
Background: Ketamine may be used to manage pain and agitation that is refractory to what are usually considered traditional agents such as fentanyl, propofol, benzodiazepines, and dexmedetomidine; however, literature desc...
Contemporary Use of Oral Antithrombotic Agents: Focus on Dual and Triple Therapeutic Approaches [0.03%]
口服抗凝药的当代应用：双联和三联治疗策略:focus
Antoine T Jenkins,Alexander Kantorovich,Luba Burman
Antoine T Jenkins
Atherosclerotic cardiovascular disease (ASCVD) represents a long-standing health care burden in most industrialized countries. Management of ASCVD is multifaceted, and utilization of antithrombotic agents is a key component of care to reduc...