Association of an Algorithm-Generated Medication Optimization Score With Clinical Outcomes in Ambulatory Patients With Heart Failure [0.03%]
基于算法的药物优化评分与心力衰竭门诊患者的临床结局相关性研究
Mohamed S Ali,Kaitlyn M Greer,Sabah Ganai et al.
Mohamed S Ali et al.
Aims: Guideline-directed medical therapy (GDMT) implementation in heart failure with reduced ejection fraction (HFrEF) remains suboptimal. A computable algorithm was developed to generate a medication optimization score (...
Pharmacotherapeutic Controversies During Temperature Control After Out-of-Hospital Cardiac Arrest: A Semi-Structured Literature Review [0.03%]
出院心脏骤停后控制体温的药物治疗争议：一种半结构化文献回顾
Christy Cecil Forehand,Scott Thomas Benken,Melanie Madorsky et al.
Christy Cecil Forehand et al.
Post-resuscitation cardiac arrest care begins at the time of hospital admission and focuses on preventing the sequelae of ischemia-reperfusion injury, including secondary brain damage and post-cardiac arrest syndrome. Clinical practice guid...
Medication Dosing by Advanced Technologies: Promise on the Horizon but Not Without Risk [0.03%]
先进科技在药物剂量中的应用：前景光明但风险犹存
William E Dager,Jeffery F Barletta,Brian L Erstad
William E Dager
Genotype Differences and Hydroxyurea Utilization Among Adults With Moderate to Severe Sickle Cell Disease [0.03%]
中重度镰状细胞病成人患者基因型差异及羟基脲利用情况研究
Siang-Hao Cheng,Enrico M Novelli,Hyeun Ah Kang et al.
Siang-Hao Cheng et al.
Backgrounds: Hydroxyurea (HU) remains underutilized in adults with sickle cell disease (SCD) despite proven benefits. Current HU guidelines primarily target sickle cell anemia (SCA), overlooking other genotypes. ...
Harnessing the Power of Artificial Intelligence to Enhance Drug Therapy Research [0.03%]
利用人工智能增强药物治疗研究的力量
William L Baker,Alexandre Chan
William L Baker
Editorial
Pharmacotherapy. 2026 Jan 13. DOI:10.1002/phar.70105 2026
AI in ID Pharmacotherapy-We Should Not Be Afraid to Put the Car Before the Horse [0.03%]
人工智能在个体化药物治疗中的应用——我们不应惧怕本末倒置
Marc H Scheetz
Marc H Scheetz
Editorial
Pharmacotherapy. 2026 Jan 12. DOI:10.1002/phar.70103 2026
Artificial Intelligence Large Language Model-Influenced Bias on Trainees and Patients in Pharmacotherapeutic Decision Making [0.03%]
人工智能大型语言模型在药理治疗决策中对受训者和患者的影响偏见
Andrew Chantha Hean,Youngil Chang
Andrew Chantha Hean
Editorial
Pharmacotherapy. 2026 Jan 12. DOI:10.1002/phar.70100 2026
Pharmacokinetic and Pharmacodynamic Principles and Concepts Remain Relevant in the Era of Artificial Intelligence and Machine Learning [0.03%]
在人工智能和机器学习时代 药物的动态平衡原理和概念仍然具有相关性
Keith A Rodvold
Keith A Rodvold
Editorial
Pharmacotherapy. 2026 Jan 11. DOI:10.1002/phar.70097 2026
Machine Learning-Based Prediction of Prolonged Duration of Mechanical Ventilation Using Medication Data [0.03%]
基于机器学习的长时间机械通气预测研究：一种用药数据的方法
Brian Murray,Bokai Zhao,Zhetao Chen et al.
Brian Murray et al.
Introduction: Prediction algorithms for prolonged mechanical ventilation (PMV) in the intensive care unit (ICU) have rarely incorporated detailed medication data, despite medications being important causal contributors to...
Effect of Testosterone Therapy on Cytochrome P450 3A and P-Glycoprotein Activities Using Midazolam and Digoxin as Probe Substrates Among Transgender Adults [0.03%]
睾酮治疗对 transgender 成人细胞色素P450 3A和P-糖蛋白活性（使用咪达唑仑和地高辛作为探针底物）的影响
Michiko Hunter,Rene Coig,Linda Risler et al.
Michiko Hunter et al.
Background: Gender-affirming testosterone therapy is one part of the standard of care for more than 1 million transgender adults in the United States. Testosterone therapy may influence the activities of drug-metabolizing...