Response to comment on "Association of atrial fibrillation with lamotrigine: An observational cohort study" [0.03%]
拉莫三嗪与心房颤动关联的观察性队列研究——对评论的回复
Sodam Kim,Landon Welch,Bertha De Los Santos et al.
Sodam Kim et al.
Relationship of the revised anticholinergic drug scale with cultured cell-based serum anticholinergic activity and cognitive measures in older adults with mild cognitive impairment or remitted depression [0.03%]
抗胆碱药量表与培养细胞基线的血清抗胆碱活性和认知测量在轻度认知障碍或抑郁缓解期老年人中的关系
Ryan M Carnahan,Susmita Chandramouleeshwaran,Naba Ahsan et al.
Ryan M Carnahan et al.
Objective: The Anticholinergic Drug Scale (ADS) is a commonly used measure of anticholinergic exposure. This study describes an expanded and revised version of the ADS (rADS) and its relationship with cultured cell-based ...
Fluoroquinolones and the risk of aortic aneurysm or dissection: A population-based propensity score-matched German cohort study [0.03%]
氟喹诺酮类药物与主动脉瘤或夹层风险的关系：基于德国人群的倾向性评分匹配队列研究
Julia Wicherski,Jonas Peltner,Cornelia Becker et al.
Julia Wicherski et al.
Objective: To investigate the risk of aortic aneurysm or dissection associated with fluoroquinolone (FQ) prescription compared to macrolides in German routine health care data in order to replicate the recent study (Pharm...
David E Nix,Fekade Sime,Jason A Roberts
David E Nix
Background: Posaconazole is an example of a highly protein-bound drug (>98%) in which therapeutic drug monitoring (TDM) is commonplace. Total drug concentration is typically measured, and in the setting of hypoalbuminemia...
Efficacy of adjuvant use of midodrine in patients with septic shock: An open label randomized controlled trial [0.03%]
关于去甲肾上腺素抵抗性脓毒性休克患者使用米多君的疗效研究：一项开放标签随机对照试验
Nadine K El-Nagdy,Noha O Mansour,Adel Al-Hady Ahmed Diab et al.
Nadine K El-Nagdy et al.
Background: Midodrine has been primarily studied as an adjunctive oral therapy to reduce the need for vasopressors in intensive care units (ICU). Nonetheless, the available results evaluating midodrine as an adjuvant ther...
Response to comment on "Use of proton pump inhibitors and risk of severe COVID-19: A case-control study in United States Medicare beneficiaries" [0.03%]
关于“质子泵抑制剂的使用和严重新冠肺炎风险：一项美国老年医疗保险受益人的病例对照研究”的评论回复
Andrew D Mosholder,Michael Wernecke,David J Graham
Andrew D Mosholder
Pharmacokinetics of continuous infusion ceftolozane/tazobactam in two patients with extensive total body surface area burns [0.03%]
大面积烧伤患者连续输注西司他丁/ ceftolozane的药代动力学研究
Jay D Olivet,Megan Amerson-Brown,Juan J Calix et al.
Jay D Olivet et al.
Introduction: Treatment of infections in patients with burn injuries is challenging due to altered antimicrobial pharmacokinetics. Continuous infusion β-lactam therapy may be a useful antimicrobial stewardship strategy t...
Case Reports
Pharmacotherapy. 2025 Apr 15. DOI:10.1002/phar.70019 2025
Risk of acute kidney injury in dapagliflozin users with type 2 diabetes: A nationwide propensity score-matched cohort study in Korea [0.03%]
韩国2型糖尿病达格列净使用者急性肾损伤风险：一项全国性倾向评分匹配队列研究
Hee-Jin Kim,Heehyun Won,Suvin Park et al.
Hee-Jin Kim et al.
Background: Several previous studies have identified a potential risk of acute kidney injury (AKI) associated with sodium-glucose cotransporter-2 (SGLT-2) inhibitors, based on adverse event reports. However, recent Europe...
Comment on "Association of atrial fibrillation with lamotrigine: An observational cohort study" [0.03%]
关于“拉莫三嗪与心房颤动关联”的观察性队列研究报告的评论
Kui Dang,Youbin Luo
Kui Dang
Amina Ammar,Stephanie B Edwin,Rachel Whitney et al.
Amina Ammar et al.
Chronic kidney disease (CKD) is a significant global health challenge that impacts both patients and the health care system. This systematic review aims to evaluate the efficacy and safety of emerging therapeutic strategies for CKD manageme...