Evaluation of neutrophil-to-lymphocyte ratio in newly diagnosed patients receiving borte- zomib-based therapy for multiple myeloma [0.03%]
评估中西医结合治疗新生代患者的粒细胞与淋巴细胞比率
Xin Zhou,Jing Wang,Jun Xia et al.
Xin Zhou et al.
Background: The neutrophil-to-lymphocyte ratio (NLR) at diagnosis has been identified as an independent prognostic marker in several malignancies. Recently, a few studies have reported that an elevated pretreatment NLR is...
Predictive gene signatures of nodal metastasis in papillary thyroid carcinoma [0.03%]
乳头状甲状腺癌淋巴结转移的预测性基因标志物
Kyu Young Choi,Jin Hwan Kim,Il Seok Park et al.
Kyu Young Choi et al.
Background: Cervical lymph node metastases (LNM) in papillary thyroid carcinomas (PTCs) are common and develop in approximately 30-80% of PTCs. The presence of cervical LNM significantly increases the rate of locoregional...
The study of sclareol in inhibiting proliferation of osteosarcoma cells by apoptotic induction and loss of mitochondrial membrane potential [0.03%]
石竹内酯通过诱导凋亡和线粒体膜电位丧失抑制骨肉瘤细胞增殖的作用机制研究
Guoqing Duan,Su Hou,Jianjun Ji et al.
Guoqing Duan et al.
Sclareol (sclarcol) is an organic compound extracted from sage clary plants. Recent study has showed its anti-tumor effects against breast cancer, gastric carcinoma, osteosarcoma and colorectal cancer. However, its exact mechanisms in inhib...
Aberrant expression of miR-141 and nuclear receptor small heterodimer partner in clinical samples of prostate cancer [0.03%]
前列腺癌临床标本中miR-141和核受体小异二聚体伴侣蛋白表达异常检测
Maryam Khorasani,Ladan Teimoori-Toolabi,Taghi Naserpour Farivar et al.
Maryam Khorasani et al.
Background: Prostate cancer (PCa) is the second most common cancer in men worldwide. Currently, prostate-specific antigen (PSA) test and digital rectal exam are the main screening tests used for PCa diagnosis. However, du...
Combining ctnnb1 genetic variability with epidemiologic factors to predict lung cancer susceptibility [0.03%]
结合遗传和流行病学因素预测肺癌的发病风险
Xu Wang,Xiaochang Zhang,Lina Jin et al.
Xu Wang et al.
Objective: Early detection and diagnosis of lung cancer remain challenging but would improve patient prognosis. The goal of this study is to develop a model to estimate the risk of lung cancer for a given individual. ...
Smac combined with DDP can inhibit drug resistance of ovarian cancer through regulation of Survivin expression [0.03%]
Smac联合DDP通过调节Survivin表达抑制卵巢癌的耐药性
Qi Chen,Hong Zhang
Qi Chen
Ovarian cancer has the highest mortality rate among gynecological malignancies, presenting a major threat to women's life and health. It is essential to study the mechanisms of drug resistance to chemotherapy to identify ways to enhance dru...
LncRNA AB209630 inhibits gemcitabine resistance cell proliferation by regulating PI3K/AKT signaling in pancreatic ductal adenocarcinoma [0.03%]
长链非编码RNA AB209630通过调节胰腺导管腺癌的PI3K/AKT信号通路来抑制吉西他滨耐药细胞增殖
Libin Wang,Feng Wang,Li Na et al.
Libin Wang et al.
Background: Recent study revealed that abnormal long noncoding RNAs (lncRNAs) expression are association with chemotherapy resistance of pancreatic ductal adenocarcinoma (PDAC). ...
The expression of CCL18 in diffuse large B cell lymphoma and its mechanism research [0.03%]
DLBCL中CCL18的表达及其机制研究
Qianping Zhou,Lanshan Huang,Yongyao Gu et al.
Qianping Zhou et al.
Background: Molecular target therapy has become a hot spot in cancer treatment, finding effective targets for diffuse large B cell lymphoma (DLBCL) is an urgent problem. ...
Expressions of IGF-1, ERK, GLUT4, IRS-1 in metabolic syndrome complicated with colorectal cancer and their associations with the clinical characteristics of CRC [0.03%]
代谢综合征合并结直肠癌患者血清IGF-1、ERK、GLUT4、IRS-1表达及与CRC临床特征相关性分析
Jianxia Hu,Xiaoyi Liu,Jingwei Chi et al.
Jianxia Hu et al.
Background: Epidemiological data have revealed that colorectal cancer (CRC) risk is increased in patients with Metabolic syndrome. Objective: ...
Geriatric nutritional risk index is not an independent predictor in patients with diffuse large B-cell lymphoma [0.03%]
老年营养风险指数不是弥漫性大B细胞淋巴瘤患者的独立预测指标
Zhongqi Li,Qi Guo,Juying Wei et al.
Zhongqi Li et al.
Background: The prognostic value of geriatric nutritional risk index (GNRI) for diffuse large B-cell lymphoma (DLBCL) treated in the rituximab era was not clear. ...