ESR1 and PIK3CA mutational status in serum and plasma from metastatic breast cancer patients: A comparative study [0.03%]
来自转移性乳腺癌患者的血清和血浆中ESR1和PIK3CA的突变状态：一项比较研究
Takashi Takeshita,Yutaka Yamamoto,Mutsuko Yamamoto-Ibusuki et al.
Takashi Takeshita et al.
Purpose: Plasma and serum cell-free DNA (cfDNA) are useful sources of tumor DNA, but comparative investigations of the tumor mutational status between them are rare. ...
Nicholas P Hughes,Lingyun Xu,Carsten H Nielsen et al.
Nicholas P Hughes et al.
Background and objective: To monitor therapies targeted to epidermal growth factor receptors (EGFR) in non-small cell lung cancer (NSCLC), we investigated Peroxiredoxin 6 (PRDX6) as a biomarker of response to anti-EGFR ag...
Expression of adiponectin and leptin receptors in adrenal incidentaloma patients with subclinical hormone secretion [0.03%]
具有亚临床激素分泌的肾上腺偶发瘤患者中脂联素及瘦素受体表达差异分析
Anna Babińska,Rafał Pȩksa,Renata Świa Tkowska-Stodulska et al.
Anna Babińska et al.
Background: The role of adopokines in adrenal tumors' hormonal activity remains unclear. Obesity may induce arterial hypertension, disorders of carbohydrate metabolism, and is a risk factor of cardiovascular disease. In p...
MDR1 not CYP3A4 gene expression is the predominant mechanism of innate drug resistance in pediatric soft tissue sarcoma patients [0.03%]
儿科软组织肉瘤患者中由于多药耐药基因表达引起的先天性药物抵抗为主要机制而非细胞色素P450 3A4基因表达
Dora Molina-Ortiz,Carmen Torres-Zárate,Rocío Cárdenas-Cardós et al.
Dora Molina-Ortiz et al.
Background: Intratumoral up-regulation of genes coding for drug transporters and metabolizing enzymes, such as MDR1 and CYP3A4, after chemotherapy are linked to cancer drug resistance. However their expression in primary ...
Serological TK1 predict pre-cancer in routine health screenings of 56,178 people [0.03%]
基于56178例常规体检的血清TK1肿瘤标志物筛查癌前病变价值研究
Yu Wang,Xiaorong Jiang,Shasha Wang et al.
Yu Wang et al.
Background: People with biomarkers above cut-off values normally have higher risk to develop pre-malignancies and malignancies. Objective: ...
Low miR-192 expression predicts poor prognosis in pediatric acute myeloid leukemia [0.03%]
低miR-192表达预测儿童急性髓系白血病预后不良
Chunmei Tian,Lin Zhang,Xiaohua Li et al.
Chunmei Tian et al.
Background: Abnormal expression of miR-192 has been observed in a variety of human cancers, but the expression pattern of miR-192 and its prognostic value in pediatric acute myeloid leukemia (AML) is poorly known. ...
Whole blood miRNA expression analysis reveals miR-3613-3p as a potential biomarker for dedifferentiated liposarcoma [0.03%]
全血miRNA表达分析鉴定出miR-3613-3p可能是去分化脂肪肉瘤的潜在生物标志物
A Fricke,A F V Cimniak,P V Ullrich et al.
A Fricke et al.
Background: Liposarcoma constitute about 13% of all soft tissue sarcoma and are associated with a high risk of metastases. As the preoperative differentiation between benign and malign lipomatous tumors is restricted to m...
Clinical biomarkers for cancer recognition and prevention: A novel approach with optical measurements [0.03%]
癌症识别和预防的临床生物标志物：一种基于光学测量的新方法
Giuseppe Latini,Claudio De Felice,Alessandro Barducci et al.
Giuseppe Latini et al.
Cancer is the most important cause of death worldwide, and early cancer detection is the most fundamental factor for efficacy of treatment, prognosis, and increasing survival rate. Over the years great effort has been devoted to discovering...
No evidence of pancreatic ductal adenocarcinoma specific autoantibodies to Ezrin in a liquid phase LIPS immunoassay [0.03%]
一种液相LIPS免疫测定法未能检测出针对Ezrin的胰腺导管腺癌特异性自身抗体
Daniela Liberati,Ilaria Marzinotto,Cristina Brigatti et al.
Daniela Liberati et al.
Background: Sensitive and specific biomarkers of Pancreatic Ductal Adenocarcinoma (PDAC) are desperately needed to allow early diagnosis and improve patient's survival. Ezrin autoantibodies were recently described as pres...
Decreased BRMS1L expression is correlated with glioma grade and predicts poor survival in glioblastoma via an invasive phenotype [0.03%]
BRMS1L表达降低与胶质瘤分级相关，并通过侵袭表型在胶质母细胞瘤中预示不良生存结果
Jia Lv,Huyin Yang,Xiaodong Wang et al.
Jia Lv et al.
Aims: To evaluate the prognostic and clinicopathological features of glioma with BRMS1L expression. Methods: Total 120 glioma samples w...