Transcription factor KLF13 inhibits AKT activation and suppresses the growth of prostate carcinoma cells [0.03%]
转录因子KLF13通过抑制AKT活化而抑制前列腺癌细胞的生长
Qiang Wang,Ruixian Peng,Boshi Wang et al.
Qiang Wang et al.
Background: Krüppel-like factor 13 (KLF13), a member of the KLF family, is involved in the development of immunological diseases and tumor progression. However, the expression patterns and potential functions of KLF13 in...
The correlation between mammographic densities and molecular pathology in breast cancer [0.03%]
乳腺癌患者乳房X线摄影密度与分子病理的相关性研究
Yu Ji,Zhenzhen Shao,Junjun Liu et al.
Yu Ji et al.
This study aimed to analyze the correlation between mammographic density obtained by density analysis software (DAS)/radiologists visual (RV) classification with molecular subtype, and the expression levels of estrogen receptor (ER), proges...
Screening and function analysis of hub genes and pathways in hepatocellular carcinoma via bioinformatics approaches [0.03%]
生物信息学方法筛选并功能分析肝癌中的枢纽基因及通路
Liang Zhang,Yi Huang,Junjun Ling et al.
Liang Zhang et al.
Background: Liver carcinoma is a major cause of cancer-related death worldwide. Up to date, the mechanisms of liver cancerigenesis and development have not been fully understood. Multi-genes and pathways were involved in ...
Clinical potential of miR-940 as a diagnostic and prognostic biomarker in breast cancer patients [0.03%]
miR-940作为乳腺癌诊断和预后生物标志物的临床潜力
Wenjun Liu,Yongmei Xu,Hongliang Guan et al.
Wenjun Liu et al.
Background: Breast cancer remains the most invasive female malignancy worldwide. Functional role of microRNA-940 (miR-940) have been investigated in various cancer. The purpose of this study was to assess the serum miR-94...
Quantum dot-based immunofluorescent imaging and quantitative detection of DNER and prognostic value in prostate cancer [0.03%]
量子点免疫荧光成像技术在前列腺癌组织中检测DNER的表达及预后价值
Lijun Wang,Qi Wu,Shan Zhu et al.
Lijun Wang et al.
DNER, Delta/Notch-like epidermal growth factor (EGF)-related receptor, is a neuron-specific transmembrane protein carrying extracellular EGF-like repeats. The prognostic value of DNER in prostate cancer has not been evaluated. Here we showe...
Significance of preoperative ischemia- modified albumin in operable and advanced gastric cancer [0.03%]
术前缺血修饰白蛋白在可手术和进展期胃癌中的意义分析
Qing-Xing Huang,Jun Ma,Yu-Sheng Wang
Qing-Xing Huang
Background: Oxidative stress plays an important role in promoting proliferation and metastases of cancer, which can be represented by ischemia-modified albumin (IMA). The purpose of this study was to evaluate serum IMA le...
Study on the methylation status of SPINT2 gene and its expression in cervical carcinoma [0.03%]
宫颈癌组织中SPINT2基因甲基化状态及其表达水平的研究
Ning Wang,Yanci Che,Fufen Yin et al.
Ning Wang et al.
Background: Cervical cancer is one of the malignant tumors which seriously threaten the women health worldwide. SPINT2 is an endogenous inhibitor of hepatocyte growth factor activator and down regulated or even silenced i...
Upregulated miR-221/222 promotes cell proliferation and invasion and is associated with invasive features in retinoblastoma [0.03%]
miR-221/222的上调促进细胞增殖和侵袭并与视网膜母细胞瘤的浸润性表型相关
Hongqian Liu,Bofeng Cao,Yuanyuan Zhao et al.
Hongqian Liu et al.
Background and objectives: MicroRNA (miR-221/222) is frequently overexpressed in many cancers and is associated with poor prognosis. However, the role of miR-221/222 in retinoblastoma (RB) remains unclear. This study aime...
High expression of TACC2 in hepatocellular carcinoma is associated with poor prognosis [0.03%]
TACC2在肝癌中高表达并与不良预后相关
Manjul Shakya,Aijun Zhou,Danian Dai et al.
Manjul Shakya et al.
Background: Transforming acidic coiled-coil protein 2 (TACC2) is a member of TACC family proteins which is mainly involved in the stabilization of spindles and regulation of microtubule dynamics through interactions with ...
The potential predictive value of circulating immune cell ratio and tumor marker in atezolizumab treated advanced non-small cell lung cancer patients [0.03%]
外周血免疫细胞比例和肿瘤标志物预测阿特珠单抗治疗晚期非小细胞肺癌的临床价值探索性分析
Minglei Zhuo,Hanxiao Chen,Tianzhuo Zhang et al.
Minglei Zhuo et al.
Background: The PD-L1 antibody atezolizumab has shown promising efficacy in patients with advanced non-small cell lung cancer. But the predictive marker of clinical benefit has not been identified. ...