Tumor immune microenvironment of colorectal cancer identifies novel prognostic signature and potential therapeutic drugs [0.03%]
结肠癌肿瘤免疫微环境识别新的预后特征和潜在治疗药物
Weijie Fu,Yunhan Gao,Zhenhai Chen et al.
Weijie Fu et al.
Background: The tumor microenvironment (TME) is increasingly recognized as a key player in colorectal cancer biology, however, its potential for improving diagnosis, prognosis, and treatment remains unclear. The major aim of this study is t...
Diagnostic utility of lipocalin 2 and metalloproteinase 9 levels in early-stage endometrial cancer [0.03%]
早期子宫内膜癌诊断中脂钙蛋白2和基质金属蛋白酶9水平的实用价值
Songül Ünüvar,Rauf Melekoğlu,Hande Yüce et al.
Songül Ünüvar et al.
Background: Endometrial cancer (EC) is the fourth most common gynecologic malignancy among women. Histopathologic examination is considered gold-standard for diagnosis of EC. However, these examinations sometimes not be u...
L1CAM is not prognostic factor in HPV-associated adenocarcinoma and adenosquamous cell carcinoma of the uterine cervix [0.03%]
L1CAM并不是与HPV相关的子宫颈腺癌和腺鳞状细胞癌的预后因素
Jaroslav Klát,Martina Romanová,Vladimír Židlík et al.
Jaroslav Klát et al.
Background: Cervical cancer (CC) is the fourth most common malignancy. The significant prognostic factors are tumor size and lympho-vascular space invasion. Considering that these are nonspecific factors, research has bee...
Identification of RNA-binding protein RBMS3 as a potential biomarker for immunotherapy in bladder cancer [0.03%]
膀胱癌免疫治疗潜在生物标志物RBMS3的鉴定
Tarimo Fredrick Praygod,Jinlong Li,Hongwei Li et al.
Tarimo Fredrick Praygod et al.
RNA-binding protein (RBP) plays pivotal roles in the malignant progression of cancer by regulating gene expression. In this paper, we aimed to develop RBP-based prognostic signature and identify critical hub RBPs in bladder cancer (BLCA). F...
KIF18A promotes cervical squamous cell carcinoma progression by activating the PI3K/AKT pathway through upregulation of CENPE [0.03%]
KIF18A通过上调CENPE激活PI3K/AKT途径促进宫颈鳞癌进展
Fengyi Sun,Tiantian Zhao
Fengyi Sun
Background: Cervical cancer is a prevalent malignancy that significantly contributes to morbidity and mortality rates among women in developing nations. Although the association of KIF18A with various cancers has been est...
Kentaro Daiki,Yoko Kanada,Aya Nagata et al.
Kentaro Daiki et al.
Background: Endocan was reported to affect breast cancer patients negatively and was able to be detected from patients' blood. Objective: ...
Uncovering the link between human endogenous retroviruses, inflammatory pathways, and gastric cancer development [0.03%]
探究人类内源性逆转录病毒与炎症通路及胃癌发生发展之间的联系
Zhengtai Li,Hongjiang Li,Kun Fang et al.
Zhengtai Li et al.
Background: Endogenous retroviruses, previously deemed "junk" DNA, have gained attention in recent scientific studies. These inherited genomic elements are now recognized for their potential roles in diseases, especially ...
Regulation of cagA-Helicobacter on gastric PIM2 expression in gastric cancer [0.03%]
cagA-Helicobacter调节胃癌中PIM2在胃中的表达
Wenjuan Liang,Haiyan Wang,Lijuan Hong et al.
Wenjuan Liang et al.
Background: The association between infection with cagA-positive H. pylori and an elevated susceptibility to gastric cancer has been firmly established. PIM2 is known to be overexpressed in various types of cancers; howev...
Prognostic impact of invariant natural killer T cells in solid and hematological tumors; systematic review and meta-analysis [0.03%]
不变自然杀伤T细胞在实体瘤和血液系统肿瘤中的预后价值：系统评价和荟萃分析
Renad M Alhamawi,Noof Aloufi,Abeer F Alamri et al.
Renad M Alhamawi et al.
Background: Invariant natural killer T (iNKT) cells are an immune subset that purportedly link the adaptive and the innate arms of the immune system. Importantly, iNKT cells contribute to anti-cancer immunity in different...
Vitamin D receptor polymorphisms associate with the efficacy and toxicity of radioiodine-131 therapy in patients with differentiated thyroid cancer [0.03%]
维生素D受体多态性与分化型甲状腺癌患者放射性碘疗效和毒性的关联研究
Yuanhong Deng,Ying Fu,Ganghua Feng et al.
Yuanhong Deng et al.
Background: Radioiodine-131 (I-131) therapy is the common postoperative adjuvant therapy for differentiated thyroid cancer (DTC) However, methods to evaluate the efficacy and toxicity of I-131 on DTC are still lacking. ...