miR-486 inhibited osteosarcoma cells invasion and epithelial-mesenchymal transition by targeting PIM1 [0.03%]
微RNA-486通过靶向PIM1抑制骨肉瘤细胞侵袭和上皮间质转化
Yuhan Liu,Juan Zhang,Cuihong Xing et al.
Yuhan Liu et al.
Objective: Osteosarcoma is the most common malignant tumor of bone with high recurrent rate. miR-486 was downregulated and acted as a tumor suppressor in plenty of tumors. The purpose of this study was to explore how miR-...
Taurine, glutamic acid and ethylmalonic acid as important metabolites for detecting human breast cancer based on the targeted metabolomics [0.03%]
基于目标代谢组学的三甲胺-N-氧化物、谷氨酰胺和乙基丙二酸作为检测人类乳腺癌的重要代谢物
Xinyang Wang,Xinshu Zhao,Jing Chou et al.
Xinyang Wang et al.
Background: This study investigated the use of serum amino acids and organic acids profiles as the novel metabolites for screening breast cancer (BC) patients. ...
Diagnostic value of serum PIVKA-II levels for BCLC early hepatocellular carcinoma and correlation with HBV DNA [0.03%]
PIVKA-II检测诊断乙型肝炎相关早期肝癌的诊断价值及其与HBV DNA的相关性研究
Jiali Wu,Zheyi Xiang,Le Bai et al.
Jiali Wu et al.
Background: It is reported that prothrombin induced by vitamin K absence-II (PIVKA-II) has a better performance of diagnosis for HCC, and has also been known to be an independent risk factor for vascular invasion. Few stu...
Wei Ni,Lin Luo,Ping Zuo et al.
Wei Ni et al.
Long noncoding RNAs (lncRNAs) are emerging as new modulators in cancer origination and progression. The previous study found lncRNA gastric carcinoma highly expressed transcript 1 (GHET1) was significantly up-regulation in the gastric cance...
Long non-coding RNA TP73-AS1 sponges miR-194 to promote colorectal cancer cell proliferation, migration and invasion via up-regulating TGFα [0.03%]
长链非编码RNA TP73-AS1通过海绵作用miR-194来上调TGFα从而促进结直肠癌细胞增殖、迁移和侵袭的功能研究
Yu Cai,Pu Yan,Ge Zhang et al.
Yu Cai et al.
Objective: Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Recently, long non-coding RNAs (lncRNAs) were found to be critical modulators in the CRC progression. The aim of this study is to investigate the...
Integrin α6 as an invasiveness marker for hepatitis B viral X-driven hepatocellular carcinoma [0.03%]
乙型肝炎病毒X蛋白驱动的肝癌浸润标记物整合素α6的研究进展
Yi Rang Kim,Mi Ran Byun,Jin Woo Choi
Yi Rang Kim
Background: Hepatitis B virus (HBV) accounts for more than 60% of hepatocellular carcinoma (HCC) cases. However, there is limited information about the features of HBV-driven HCC that differentiate it from other types of ...
Targeting signal-transducer-and-activator-of-transcription 3 sensitizes human cutaneous melanoma cells to BRAF inhibitor [0.03%]
靶向信号转导及转录激活因子3可使人类黑色素瘤细胞对BRAF抑制剂敏感化
Xiaohui Wang,Huajun Qu,Yinghe Dong et al.
Xiaohui Wang et al.
Melanoma treatment with the BRAF V600E inhibitor vemurafenib provides therapeutic benefits but the common emergence of drug resistance remains a challenge. To define molecular mechanisms of vemurafenib resistance, we generated A375-R, WM35-...
Correlations of TNM staging and lymph node metastasis of gastric cancer with MRI features and VEGF expression [0.03%]
胃癌的TNM分期及淋巴结转移与MRI表现和VEGF表达的关系
Lan Pang,Jing Wang,Yong Fan et al.
Lan Pang et al.
Objective: To investigate the correlations of expression of vascular endothelial growth factor (VEGF) in gastric cancer tissues of patients and magnetic resonance imaging (MRI) features with clinical tumor-node-metastasis...
Correlations of MRI manifestations with survivin gene expression in primary hepatic carcinoma [0.03%]
原发性肝癌MRI征象与 survivin 基因表达相关性研究
Jian Li,Rui Ma,Zhenbin Cao et al.
Jian Li et al.
Objective: To investigate the correlations of magnetic resonance imaging (MRI) manifestations with survivin gene expression in primary hepatocellular carcinoma (HCC). ...
Annexin A5 overexpression might suppress proliferation and metastasis of human uterine cervical carcinoma cells [0.03%]
annexin a5过表达可能通过影响wnt/β-catenin信号通路抑制子宫颈癌细胞的增殖和转移
Xin Li,Wenyi Ma,Xiaojie Wang et al.
Xin Li et al.
Background: Annexin A5 (ANXA5) is a kind of Ca2+-dependent phospholipid binding protein which is involved in cell membrane dynamics and organization. Recent data showed that ANXA5 might involve in tumorigenesis. ...