Frameshift mutation of candidate tumor suppressor genes QK1 and TMEFF2 in gastric and colorectal cancers [0.03%]
胃癌和结直肠癌候选抑癌基因QK1和TMEFF2的无义突变
Ha Yoon Mo,Yun Sol Jo,Nam Jin Yoo et al.
Ha Yoon Mo et al.
Background: Both QKI and TMEFF2 genes are considered putative tumor suppressor genes (TSGs). In gastric (GC) and colorectal (CRC) cancers, downregulation of their expressions is known to be frequent. However, QKI and TMEF...
miR-378 serves as a prognostic biomarker in cholangiocarcinoma and promotes tumor proliferation, migration, and invasion [0.03%]
MiR-378在肝内胆管癌中发挥预后标记物作用并促进肿瘤增殖、迁移和侵袭
Zhijian Zhou,Jing Ma
Zhijian Zhou
MicroRNAs (miRNAs) have been demonstrated that play a critical role in tumorigenesis. The aim of this study is to identify the functional role of miR-378 in cholangiocarcinoma (CCA). Quantitative real-time polymerase chain reaction (qRT-PCR...
ADP-ribosylation factor-like 4C predicts worse prognosis in endometriosis-associated ovarian cancers [0.03%]
ADP核糖基化因子样蛋白4C预测子宫内膜异位相关卵巢癌预后较差
Shiro Wakinoue,Tokuhiro Chano,Tsukuru Amano et al.
Shiro Wakinoue et al.
Background: Endometrioid ovarian carcinoma and clear cell ovarian carcinoma are both classified as endometriosis-associated ovarian cancer (EAOC). Despite the high rates of recurrence and mortality of EAOC, no prognostic ...
The altered expression levels of miR-186, miR-494 and miR-3651 in OSCC tissue vary from those of the whole blood of OSCC patients [0.03%]
与口腔鳞癌外周血相比，miR-186、miR-494和miR-3651在OSCC组织中的表达水平不同
Jutta Ries,Christoph Baran,Falk Wehrhan et al.
Jutta Ries et al.
Background: Altered expressions of miR-186, miR-494 and miR-3651 in whole blood of OSCC patients have already been demonstrated. However, nothing is known about their expression in tumor tissues. This study aimed at evalu...
Predictive significance of serum dipeptidyl peptidase-IV in papillary thyroid carcinoma [0.03%]
血清二肽基肽酶-IV在乳头状甲状腺癌的预测意义
Nan Zhang,Xiaoqiang Cong,Dan Zhou et al.
Nan Zhang et al.
Background: The significance of serum dipeptidyl peptidase-IV (DPP-IV) in papillary thyroid carcinoma (PTC) has not been elucidated. Objective: ...
Metabolo-volumetric parameters of 18F-FDG-PET can predict expression of EGFR and HIF 1alpha in uterine cervical cancer [0.03%]
氟脱氧葡萄糖正电子发射断层扫描代谢容积参数可预测宫颈癌表皮生长因子受体及缺氧诱导因子1α表达
Alexey Surov,Hans Jonas Meyer,Anne-Kathrin Höhn et al.
Alexey Surov et al.
Background: The aim of our study was to investigate possible relationships between 18F-FDG-PET parameters and clinically relevant histopathological findings in patients with cervical cancer (CC). ...
MicroRNA-539 inhibits the progression of Wilms' Tumor through downregulation of JAG1 and Notch1/3 [0.03%]
microRNA-539通过下调JAG1及Notch1/3抑制Wilm's肿瘤的发展
Hailong Su,Xuebo Wang,Jingjing Song et al.
Hailong Su et al.
Background: Previous studies demonstrated that miR-539 play an important role in the carcinogenesis of some cancers. The aim of the present study was to determine the role of miR-539 in the pathogenesis of Wilms' Tumor (W...
Serum miR-100 is a potential biomarker for detection and outcome prediction of glioblastoma patients [0.03%]
血清miR-100可作为胶质母细胞瘤患者检测和预后预测的潜在生物标志物
Huiping Zhang,Jianfeng Wang,Zhanying Wang et al.
Huiping Zhang et al.
Background: It is well known that some circulating microRNAs (miRNAs) are highly stable and might serve as promising biomarkers for many types of human cancer including glioblastoma (GBM). However, the potential clinical ...
Association between genetic polymorphisms in long non-coding RNAs and pancreatic cancer risk [0.03%]
长链非编码RNA基因多态性与胰腺癌发病风险的相关性研究
D Moschovis,E Vasilaki,M Tzouvala et al.
D Moschovis et al.
Background: Long non-coding RNAs (lncRNAs) are emerging as candidate biomarkers of cancer, having regulatory functions in both oncogenic and tumor-suppressive pathways. Concerning pancreatic cancer (PC), deregulation of l...
Targeted regulation by ROCK2 on bladder carcinoma via Wnt signaling under hypoxia [0.03%]
缺氧条件下ROCK2通过Wnt信号通路调控膀胱癌细胞侵袭转移的机制研究
Junfeng Luo,Zhengda Lou,Junzheng Zheng
Junfeng Luo
Bladder cancer is frequently occurred in urinary system and has complicated pathogenesis factors including both genetics and environmental factors that have not been fully illustrated. Hypoxia can further induce tumor progression. ROCK2 has...