Estimated proportion of cancer deaths not addressed by current cancer screening efforts in the United States [0.03%]
估计出当前美国癌症筛查工作中未涉及的癌症死亡比例
Joshua J Ofman,William Dahut,Ahmedin Jemal et al.
Joshua J Ofman et al.
BackgroundIt is unclear what proportion of the population cancer burden is covered by current implementation of USPSTF A/B screening recommendations.ObjectiveWe estimated the proportion of all US cancer deaths caused by cancer types not cov...
Biomarkers in lung cancer diagnosis and bronchoscopy: Current landscape and future directions [0.03%]
肺癌诊断和支气管镜检查中的生物标志物：现状与未来方向
Nina A Thomas,Melissa L New
Nina A Thomas
Lung cancer is the leading cause of cancer death world-wide. Along the entire timeline of lung cancer identification, diagnosis and treatment, clinicians and patients face challenges in clinical decision-making that could be aided by useful...
A nomogram based on preoperative NLR predicts distant metastasis of urothelial carcinoma of the bladder [0.03%]
基于术前NLR的Nomogram预测膀胱尿路上皮癌远处转移
Xingxing Zhang,Bin Zhang,Yang He et al.
Xingxing Zhang et al.
BackgroundDistant metastasis (DM) remains the most commonly reported cause of death in patients with urothelial carcinoma of the bladder (UCB).ObjectiveWe aimed to develop a robust prognostic model to assess the risk of DM in patients with ...
Identification of the molecular subtype and prognostic characteristics of lung adenocarcinoma based on CD8+ T cell-related gene signature [0.03%]
基于CD8+T细胞相关基因特征识别肺腺癌的分子亚型和预后特性
Keke Tang,Ji Shen,Dan Liu et al.
Keke Tang et al.
BackgroundLung adenocarcinoma (LUAD) stands as a major respiratory malignancy with high mortality. With the advent of immunotherapy, new therapeutic avenues have emerged in cancer treatment.ObjectiveOur focus aimed at developing a CD8+ T ce...
A Glycolysis and gluconeogenesis-related model for breast cancer prognosis [0.03%]
与糖酵解和糖异生相关的乳腺癌预后模型
Penglu Yang,Xiong Jiao
Penglu Yang
BackgroundBreast cancer is a malignant tumor with high morbidity and mortality, which seriously endangers the health of women around the world. Biomarker-based exploration will be effective for better diagnosis, prediction and targeted ther...
Pan-cancer genetic profiles of mitotic DNA integrity checkpoint protein kinases [0.03%]
有丝分裂DNA完整检查点蛋白激酶的泛癌遗传特征
Ayana Meegol Rasteh,Hengrui Liu,Panpan Wang
Ayana Meegol Rasteh
Background: The mitotic DNA integrity checkpoint signaling pathway is potentially involved in cancers that regulate genomic stability where protein kinases play a pivotal role. 16 total protein kinase genes are involved in this pathway: ATM...
Predictive role of HPGD gene in carcinogenesis and immune environment monitoring in human cervical cancer [0.03%]
HPGD基因在人类宫颈癌的发生及免疫环境监测中的预测作用研究
Mingzhu Zhai,Weihua Yang,Chen Zou et al.
Mingzhu Zhai et al.
Background15-Hydroxyprostaglandin dehydrogenase (15-PGDH, gene symbol HPGD) is considered a tumor suppressor, and its expression is often proportional to the anticancer response. However, the clinical significance of HPGD/15-PGDH in predict...
High TCTA expression is an adverse prognostic biomarker in acute myeloid leukemia [0.03%]
高TCTA表达是急性髓系白血病的不良预后生物标志物
Yunli Shao,Tong Qin
Yunli Shao
BackgroundAcute myeloid leukemia (AML) prognosis varies greatly, underscoring the need for novel biomarkers to improve patient stratification. T-cell leukemia translocation-associated gene (TCTA) has emerged as a potential player in hematol...
A fatty acid metabolism-related genes model for predicting the prognosis and immunotherapy effect of lung adenocarcinoma [0.03%]
用于预测肺腺癌预后和免疫治疗效果的脂肪酸代谢相关基因模型
Lingxue Tang,Tong Wang
Lingxue Tang
ObjectiveLung adenocarcinoma (LUAD) is a common and highly heterogeneous malignancy cancer with increasing morbidity and mortality. Dysregulation of fatty acid metabolism (FAM) has been identified as a key regulator of LUAD progression. Our...
Hsa_circ_0002346 inhibits proliferation, invasion, and migration of breast cancer cells and promotes apoptosis: A novel potential biomarker for breast cancer [0.03%]
Hsa_circ_0002346抑制乳腺癌细胞的增殖，侵袭和迁移并促进凋亡：乳腺癌的一种新型潜在生物标志物
Yixin Zhou,Linyi Wang,Wangjin Xu et al.
Yixin Zhou et al.
BackgroundCircular RNA hsa_circ_0002346 has been implicated in the progression of various tumors, yet the functional role in breast cancer remains poorly understood. This study aimed to investigate the significance of hsa_circ_0002346 in br...