Circ0001429 regulates progression of bladder cancer through binding miR-205-5p and promoting VEGFA expression [0.03%]
Circular RNA Circ0001429通过结合miR-205-5p促进VEGFA表达从而促进膀胱癌进展
Wenfeng Cao,Youguang Zhao,Liang Wang et al.
Wenfeng Cao et al.
Objective: This study investigates expressions of circ0001429, miR-205-5p and vascular endothelial growth factor (VEGFA) in bladder cancer tissues and their effects on the proliferation, migration and apoptosis. ...
Clinical significance of the expression of long non-coding RNA PVT1 in glioma [0.03%]
长非编码RNA PVT1在胶质瘤中的表达及临床意义研究
Jiyang Fang,Jianyue Huang
Jiyang Fang
Background: Glioma is the most common primary malignant tumor in the nervous system. Objective: To investigate the expression of long n...
Schizandrin A inhibits proliferation, migration and invasion of thyroid cancer cell line TPC-1 by down regulation of microRNA-429 [0.03%]
五味子素A通过下调microRNA-429抑制甲状腺癌细胞系TPC-1的增殖、迁移和侵袭能力
Qiuli Ding,Xiaoyan Li,Yongcun Sun et al.
Qiuli Ding et al.
Objective: Schizandrin A (SchA) exerts anticancer potential. However, the effects of SchA on thyroid cancer (TC) have not been clear illuminated. Therefore, we investigated the effects of SchA on TC cell line TPC-1 and th...
Clinical significance of serum miR-25 as a diagnostic and prognostic biomarker in human gastric cancer [0.03%]
血清miR-25作为胃癌诊断和预后生物标志物的临床意义
Ying Kong,Liang Ning,Fei Qiu et al.
Ying Kong et al.
Background and objective: MicroRNAs (miRNAs) are under investigation as novel diagnostic and prognostic biomarkers in several malignancies, including gastric cancer (GC). miR-25 was overexpressed in GC tissues, and higher...
SIRT5 downregulation is associated with poor prognosis in glioblastoma [0.03%]
SIRT5低表达与胶质母细胞瘤预后不良相关
Xi Chen,Zhijie Xu,Shuangshuang Zeng et al.
Xi Chen et al.
Objective: Sirtuins (SIRT) are NAD+-dependent protein deacetylases that are involved in the regulation of cancer-associated pathways. However, the biological role of these deacetylases remains elusive in glioblastoma (GBM...
Downregulation of long noncoding RNA LINC00460 expression suppresses tumor growth in vitro and in vivo in gastric cancer [0.03%]
长非编码RNA LINC00460表达下调通过体内和体外实验抑制胃癌生长
Shuhua Zhang,Jianqun Xu,Hongjuan Wang et al.
Shuhua Zhang et al.
Background: Long noncoding RNA have been indicated to be involved in tumor development. However, the role of LINC00460 in gastric cancer (GC) still remains large unknown. The current study is designed aiming at determinin...
Upregulation of lncRNA AB073614 functions as a predictor of epithelial ovarian cancer prognosis and promotes tumor growth in vitro and in vivo [0.03%]
长链非编码RNA AB073614的上调作为预测卵巢癌预后和促进体内体外肿瘤生长的指标的功能研究
Saitian Zeng,Shikai Liu,Jing Feng et al.
Saitian Zeng et al.
Backgrounds: Upregulation of lncRNA AB073614 is found in some cancer types and involved in tumor development and progression including ovarian cancer. However, the clinical value and functional role of lncRNA AB073614 in ...
Ginsenoside impedes proliferation and induces apoptosis of human osteosarcoma cells by down-regulating β-catenin [0.03%]
人参皂苷通过下调β-连环素抑制人骨肉瘤细胞增殖并诱导其凋亡
Xue-Feng Li,Guo-Qing Zhao,Long-Yun Li
Xue-Feng Li
Background: Osteosarcoma (OS) is the most commonly occurred primary bone malignancy with high incident rates among children and adolescents. In pharmacologic treatment, the drug ginsenoside has been shown to exert antican...
CCDC6, a gene product in fusion with different protoncogenes, as a potential chemotherapeutic target [0.03%]
与多种致癌基因融合的基因产物CCDC6作为潜在化疗靶点
Aishwarya Laxmi,Pawan Gupta,Jeena Gupta
Aishwarya Laxmi
Cancer, a deadly disease is characterized by abnormal cell growth with the potential to invade to other parts of the body. Most cancers start due to changes at gene level that happen over a person's lifetime when DNA repair system becomes f...
Long non-coding RNA MAGI2-AS3 inhibits breast cancer cell migration and invasion via sponging microRNA-374a [0.03%]
长链非编码RNA MAGI2-AS3通过竞争性内源RNA网络海绵作用于微小核糖核酸-374a抑制乳腺癌细胞迁移和侵袭功能机制研究
Shanmei Du,Wei Hu,Yi Zhao et al.
Shanmei Du et al.
Long non-coding RNAs (lncRNAs) are non-protein-coding transcripts that play important roles in tumorigenesis and tumor progression. Our study aimed to explore the role of lncRNA MAGI2-AS3 in breast cancer metastatic progression. In the pres...