Correlation of BRCA2 gene mutation and prognosis as well as variant genes in invasive urothelial carcinoma of the bladder [0.03%]
BRCA2基因突变与侵袭性膀胱尿路上皮癌预后及变异基因的相关性研究
Shihang Kuang,Huafu Li,Jianhua Feng et al.
Shihang Kuang et al.
Background: This study aimed to investigate the correlation of BRCA2 gene mutation and prognosis as well as variant genes in patients with invasive urothelial carcinoma of the bladder. It predicted and explored the possib...
Impact of AIB1 expression on the prognosis of upper tract urothelial carcinoma after radical nephroureterectomy [0.03%]
AIB1表达对根治性肾输尿管全长切除术后上尿路尿路上皮癌患者预后的影响
Yong Huang,Junjie Cen,Jinhuan Wei et al.
Yong Huang et al.
Background: Amplified in breast cancer 1 (AIB1) is a candidate oncogene in human breast cancer, which has been identified to be amplified and overexpressed in several types of other human cancers. Abnormalities of AIB1 an...
MiR-1236-3p serves as a new diagnostic and prognostic biomarker for gastric cancer [0.03%]
MiR-1236-3p可作为胃癌诊断和预后的新生物标志物
Jia-Xiang An,Zhao-Sheng Ma,Ming-Hui Ma et al.
Jia-Xiang An et al.
Background: The microRNA plays an important role in tumor progression. MiR-1236-3p acts as a tumor suppressor in various malignancies. Objective: ...
MicroRNA-98 targets HMGA2 to inhibit the development of retinoblastoma through mediating Wnt/β-catenin pathway [0.03%]
微小核糖核酸98通过介导Wnt/β-catenin信号通路抑制HMGA2基因表达从而抑制视网膜母细胞瘤发展
Wei Li,Junmei Wang,Dongqing Zhang et al.
Wei Li et al.
Background: Recently, the incidence and mortality of retinoblastoma (RB) have gradually increased. Many studies support the pivotal role of microRNAs (miRNAs) in the pathogenesis of RB. Alternation of microRNA-98 (miR-98)...
Nan Ma,Lizhe Zhu,Liu Yang et al.
Nan Ma et al.
S100 family is made up of at least 20 calcium-binding proteins which are involved in many cellular processes. The prognostic values of individual S100 member in ovarian cancer patients are still unknown. In this study, we performed a detail...
Shankargouda Patil,Niraj Babu,Tejaswini Subbannayya et al.
Shankargouda Patil et al.
Background: Shisha smoking has been associated with multiple diseases including oral cancer. However, a mechanistic study to investigate alteration of secreted proteins in oral cells due to shisha smoking is lacking. ...
Prognostic significance of LAPTM4B and p27kip1 expression in triple-negative breast cancer [0.03%]
LAPTM4B和p27kip1在三阴性乳腺癌中的预后价值
Xuelu Li,Chen Song,Kainan Wang et al.
Xuelu Li et al.
Backgroud: Triple-negative breast cancer (TNBC) is associated with an aggressive phenotype and poor prognosis, and the lack of druggable markers leads to the unavailability of targeted therapies. Thus, there is an urgent ...
MiR-342 regulates cell proliferation and apoptosis in hepatocellular carcinoma through Wnt/β-catenin signaling pathway [0.03%]
微RNA-342通过Wnt/β-连锁蛋白信号通路调节肝细胞癌的增殖和凋亡
Chang Lu,Shengnan Jia,Shutao Zhao et al.
Chang Lu et al.
Background: Hepatocellular carcinoma (HCC) is one of the most common malignancies, and its global morbidity and mortality are increasing. Previous studies confirmed that miR-342 was involved in the development and progres...
MicroRNA-146-5p promotes proliferation, migration and invasion in lung cancer cells by targeting claudin-12 [0.03%]
microRNA-146-5p通过靶向闭锁素-12促进肺癌细胞的增殖、迁移和侵袭
Xianghong Sun,Shichao Cui,Xiaofeng Fu et al.
Xianghong Sun et al.
MicroRNAs (miRNAs) have been regarded as important regulators in different pathological processes of cells. Abnormal expression of miRNAs is frequently associated with cell proliferation, metastasis and apoptosis in various cancers. This st...
Anca Botezatu,Iulia V Iancu,Adriana Plesa et al.
Anca Botezatu et al.
Background: Thyroid carcinoma is the most common endocrine malignancy worldwide. Changes in DNA methylation can cause silencing of normally active genes, especially tumour suppressor genes (TSG) or activation of normally ...