Golgi phosphoprotein 3 (GOLPH3) promotes endometrial carcinoma cell invasion and migration by regulating the epithelial-mesenchymal transition [0.03%]
高尔基体磷蛋白3（GOLPH3）通过调节上皮间质转化促进子宫内膜癌细胞侵袭和迁移
Yu Wen,Xiaoqing Tan,Xia Wu et al.
Yu Wen et al.
Background: Golgi phosphoprotein 3 (GOLPH3) is a novel oncogene overexpressed in several human cancers, but specific contributions to endometrial carcinoma (EC) have not been examined. The aims of this study were to evalu...
Glutamate dehydrogenase inhibits tumor growth in gastric cancer through the Notch signaling pathway [0.03%]
谷氨酸脱氢酶通过诺特定理信号途径抑制胃癌肿瘤生长
You-Jun Wu,Zi-Long Hu,Shi-Dong Hu et al.
You-Jun Wu et al.
Glutamate dehydrogenase (GDH) is a key enzyme in glutaminolysis and can regulate allosteric functions. Immunohistochemical study found that GDH expressed in gastric cancer cell cytoplasm and membrane, and a few located in the nucleus, rangi...
Screening of key genes and prediction of therapeutic agents in Arsenic-induced lung carcinoma [0.03%]
砷致肺癌关键基因筛选及治疗药物预测
Liang Zhang,Yu Huang,Junjun Ling et al.
Liang Zhang et al.
Background: Evidence indicates that inorganic arsenic (iAs) can directly damage cells and result in malignant transformation with unclear complicated mechanisms. In the present study, we aimed to explore the possible mole...
PELP1 is a novel oncogene in gastric tumorigenesis and negatively regulated by miR-15 family microRNAs [0.03%]
胃肿瘤发生的新癌基因PELP1及其负调控因子miR-15家族微小核糖核酸
Chuanyu Ma,Chuanna Miao,Chenghong Wang et al.
Chuanyu Ma et al.
Backgroud: Gastric cancer (GC) is one of the leading causes of cancer-related death in East Asia and some South American countries, but its mechanism has not been clarified clearly. Proline-, glutamic acid-, and leucine-r...
Prognostic impact of circulating monocyte subsets in pediatric solid tumors [0.03%]
儿童实体瘤中循环单核细胞亚群的预后价值
Asmaa M Zahran,Amal Rayan,Heba Abdel Razik Sayed et al.
Asmaa M Zahran et al.
Background and aim: We aimed to quantify monocyte subsets in newly diagnosed pediatric patients with solid tumors at South Egypt Cancer Institute (SECI) and Assiut University Hospital (AUH), and investigate their roles in...
Eukaryotic translation initiation factor 3B is overexpressed and correlates with deteriorated tumor features and unfavorable survival profiles in cervical cancer patients [0.03%]
宫颈癌患者中欧氏翻译起始因子3B高表达并与肿瘤不良特征和预后不良有关
Pengfeng Zhu,Qingqing Tan,Wen Jiang et al.
Pengfeng Zhu et al.
Objective: This study aimed to detect the expression of eukaryotic translation initiation factor 3B (EIF3B) and investigate its correlation with tumor features and survival in cervical cancer patients. ...
Expression of PIWIL2 in oral cancer and leukoplakia: Prognostic implications and insights from tumors [0.03%]
PIWIL2在口腔癌和白斑中的表达：预后意义及肿瘤的启示
Shan Wang,Fang Li,Haixia Fan et al.
Shan Wang et al.
PIWIL2 is a human Argonaute protein, which is guided by small RNAs to its targets, plays a role in germ cell maintenance and has been proposed to be expressed in precancerous stem cells and tumor stem cells. However, the significance of PIW...
Fucosyltransferase 8 deficiency suppresses breast cancer cell migration by interference of the FAK/integrin pathway [0.03%]
α1,3岩藻糖转移酶8缺陷通过干扰FAK/整合素信号通路抑制乳腺癌细胞迁移
Deshui Liu,Zhiying Gao,Liling Yue
Deshui Liu
Background and objective: Fucosyltranferase 8 (FUT8), which catalyzes core fucosylation of glycopeptides, plays important roles in cancer development. In this study, we aimed to explore the influence of FUT8 expression on...
Downregulation of serum exosomal miR-150-5p is associated with poor prognosis in patients with colorectal cancer [0.03%]
血清外泌体miR-150-5p下调与结直肠癌患者预后不良相关
Shui-Lan Zou,Yue-Li Chen,Zhen-Zhen Ge et al.
Shui-Lan Zou et al.
Growing evidence have revealed the serum exosomal miRNAs emerged as biomarkers for various cancer types, including colorectal cancer (CRC). Here, we sought to explore the potential clinical significance of serum exosomal miR-150-5p in CRC. ...
Overexpression of connective tissue growth factor is associated with tumor progression and unfavorable prognosis in endometrial cancer [0.03%]
结缔组织生长因子在子宫内膜癌过表达及其与肿瘤进展和预后不良的关系研究
Xue-Ting Li,Jia-Yu Li,Guang-Chun Zeng et al.
Xue-Ting Li et al.
Objectives: This study was to explore the prognostic value of connective tissue growth factor (CTGF) expression in endometrial cancer (EC). Methods: ...