Lactate dehydrogenase and serum tumor markers for predicting metastatic status in geriatric patients with lung adenocarcinoma [0.03%]
老年肺腺癌患者中乳酸脱氢酶和血清肿瘤标志物对转移状态的预测价值
Xiaolu Ren,Yixun Zhang,Yi Lyu et al.
Xiaolu Ren et al.
Background: No tumor biomarker (TM) is available for de novo metastatic lung adenocarcinoma. Objective: To examine the serum levels of ...
Interleukin-1beta and Caspase-3 expression serve as independent prognostic markers for metastasis and survival in oral squamous cell carcinoma [0.03%]
白介素-1β和半胱天冬酶-3的表达可作为独立预后标志物预测口腔鳞状细胞癌的转移和生存率
Preeti Singh,Dominic Augustine,Roopa S Rao et al.
Preeti Singh et al.
Background: The Indian subcontinent has the highest incidence and prevalence of oral squamous cell carcinoma (OSCC). Inflammation and apoptosis are two emerging hall marks of cancer that might play a significant role in t...
Role of Smac, survivin, XIAP, and Omi/HtrA2 proteins in determining the chemotherapeutic response of patients with cervical cancer treated with neoadjuvant chemotherapy [0.03%]
Smac、survivin、XIAP和Omi/HtrA2蛋白在宫颈癌新辅助化疗中作用及意义研究
Tianyi Ye,Hongwen Yao,Yang Xu et al.
Tianyi Ye et al.
Neoadjuvant chemotherapy (NACT) followed by radical surgical hysterectomy and pelvic lymph node dissection is considered an effective method to treat patients with bulky stage IB-IIA cervical cancer, but not all patients benefit from NACT. ...
Serum thrombomodulin as a metastatic and prognostic marker in soft tissue sarcomas [0.03%]
血浆蛋白thrombomodulin作为软组织肉瘤转移和预后标志物的作用研究
Kunihiro Asanuma,Tomoki Nakamura,Yumiko Asanuma et al.
Kunihiro Asanuma et al.
Background: Thrombomodulin (TM) has multiple biological functions and modulates not only anti-coagulation, but also cell proliferation, adhesion, and anti-inflammation activities. The main function of TM is to activate th...
MicroRNA-429 inhibits cancer cell proliferation and migration by targeting the AKT1 in melanoma [0.03%]
microRNA-429通过靶向AKT1抑制黑色素瘤细胞增殖和迁移
Deshun Huang,Fuxi Wang,Wenzhong Wu et al.
Deshun Huang et al.
MicroRNAs (miRNAs; miR) have been proven to act as both oncogenes and tumor suppressors. However, the mechanism of action of miR429 in melanoma cells remains to be elusive. The present study aims to explain the functional role and mechanism...
Overexpression of miR-939-3p predicts poor prognosis and promotes progression in lung cancer [0.03%]
miR-939-3p过表达与肺癌不良预后及进展有关
Xia Han,Chunjuan Du,Yinghai Chen et al.
Xia Han et al.
Background: Lung cancer is the main cancer-related deaths worldwide. In this study, we explored the clinical prognostic significance and functional role of miR-939-3p in lung cancer. ...
Screening key lncRNAs for human lung adenocarcinoma based on machine learning and weighted gene co-expression network analysis [0.03%]
基于机器学习和加权基因共表达网络分析的人类肺腺癌关键lncRNA筛查研究
Yu Wang,Junfeng Fu,Ze Wang et al.
Yu Wang et al.
Background: Lung adenocarcinoma (LUAD) accounts for a significant proportion of lung cancer and there have been few diagnostic and therapeutic targets for LUAD due to the lack of specific biomarker. The aim of this study ...
Bivalent property of intra-platelet VWF in liver regeneration and HCC recurrence: A prospective multicenter study [0.03%]
血小板内VWF在肝再生和HCC复发的双重作用:一项前瞻性多中心研究
Bibek Aryal,Munekazu Yamakuchi,Toshiaki Shimizu et al.
Bibek Aryal et al.
Background and aims: A striking difference has been observed in structure and functional properties between plasma and platelet von Willebrand factor (VWF). While the existing evidence has revealed a clinical relevance of...
Multicenter Study
Cancer biomarkers : section A of Disease markers. 2019;26(1):51-61. DOI:10.3233/CBM-190168 2019
Spinal versus intracranial meningioma: Expression of E-cadherin and Fascin with relation to clinicopathological features [0.03%]
脊柱与颅内脑膜瘤的E-钙黏着蛋白和Fascin表达及其临床病理特征的关系研究
Abd AlRahman Mohammad Foda,Mariya Syed Alam,Nadeem Ikram et al.
Abd AlRahman Mohammad Foda et al.
Background: E-cadherin and Fascin are adhesive proteins that are expressed in many tumors. It was supposed that loss of expression of these proteins is associated with increased aggressiveness of the tumor. Whether spinal...
Long non-coding RNA LINC00641 suppresses non-small-cell lung cancer by sponging miR-424-5p to upregulate PLSCR4 [0.03%]
长链非编码RNA LINC00641通过海绵吸附miR-424-5p来上调PLSCR4以抑制非小细胞肺癌
Yi Li,Lily Zhao,Pei Zhao et al.
Yi Li et al.
Non-small cell lung cancer (NSCLC) , as the most prevalent type of lung carcinoma with high severity, is of urgent necessity to be investigated for novel therapeutic strategies. Long non-coding RNAs (lncRNAs) are notable for their participa...