Circulating tumor DNA sequencing for colorectal cancers: A comparative analysis of colon cancer and rectal cancer data [0.03%]
结直肠癌循环肿瘤DNA测序：基于结肠和直肠癌症数据的比较分析
Kaibin Huang,Hongyue Qu,Xiaoni Zhang et al.
Kaibin Huang et al.
Background: Circulating tumor DNA (ctDNA) has been recognized as a promising biomarker for colorectal cancer (CRC) early diagnosis and postoperative monitoring. However, we hypothesize that the clinical value of ctDNA seq...
Comparative Study
Cancer biomarkers : section A of Disease markers. 2019;26(3):313-322. DOI:10.3233/CBM-190257 2019
MiR-511 mimic transfection inhibits the proliferation, invasion of osteosarcoma cells and reduces metastatic osteosarcoma tumor burden in nude mice via targeting MAPK1 [0.03%]
miR-511靶向MAPK1抑制成骨细胞增殖、侵袭及裸鼠肺转移瘤负荷
Junxue Wu,Chao Zhang,Lu Chen
Junxue Wu
Osteosarcoma, a highly aggressive cancer, can rapidly metastasize to distant organs such as lung, liver, brain. Despite much progress in the therapeutic regime has been made, the prognosis of osteosarcoma remains poor. In present study, mic...
MiR-652 serves as a prognostic biomarker in gastric cancer and promotes tumor proliferation, migration, and invasion via targeting RORA [0.03%]
MiR-652在胃癌中的预后作用及其通过靶向RORA促进肿瘤增殖、迁移和侵袭的作用机制
Juncheng Li,Xiaoming Zou
Juncheng Li
Purpose: MicroRNAs (miRNAs) have been reported to be involved in tumorigenesis. The aim of this study was to investigate the functional role and prognostic value of miR-652 in gastric cancer (GC). ...
A chemokine/chemokine receptor signature potentially predicts clinical outcome in colorectal cancer patients [0.03%]
有望预测结直肠癌患者临床预后的细胞因子/细胞因子受体特征标志
Andrew Mitchell,Sarrah L Hasanali,Daley S Morera et al.
Andrew Mitchell et al.
Background: Differential expression of chemokines/chemokine receptors in colorectal cancer (CRC) may enable molecular characterization of patients' tumors for predicting clinical outcome. ...
MicroRNA-935 acts as a prognostic marker and promotes cell proliferation, migration, and invasion in colorectal cancer [0.03%]
microRNA-935可作为结直肠癌预后标志物并促进肿瘤细胞增殖、迁移和侵袭
Ying Huang,Wenfeng Xiao,Xiuli Jiang et al.
Ying Huang et al.
Colorectal cancer (CRC) is a common cause of cancer-related deaths worldwide. MicroRNA-935 (miR-935) has been reported to be involved in several cancers. In the present study, we aimed to investigate the role of miR-935 in the progression o...
Increased expression of miR-181d is associated with poor prognosis and tumor progression of gastric cancer [0.03%]
miR-181d过度表达与胃癌不良预后及肿瘤进展有关
Zhichun Li,Qingbo Guo,Yugang Lu et al.
Zhichun Li et al.
Aberrant expression of miR-181d has been noted in multiple human cancers, but its role in gastric cancer (GC) remains unclear. The aim of this study was to investigate the expression, clinical significance and functional role of miR-181d in...
A nine-long non-coding RNA signature for prognosis prediction of patients with lung squamous cell carcinoma [0.03%]
一种用于肺癌鳞状细胞癌患者预后预测的九种长链非编码RNA标志物签名
Ge Huang,Qing Huang,Zilu Xie et al.
Ge Huang et al.
Background: Lung squamous cell carcinoma (LUSC) is malignant disease with poor therapeutic response and unfavourable prognosis. Objective: ...
Evaluation of the liquid biopsy for the detection of BRAFV600E mutation in metastatic melanoma patients [0.03%]
评估液态活检在转移性黑色素瘤患者中检测BRAF V600E突变的效果
Francesca Salvianti,Daniela Massi,Vincenzo De Giorgi et al.
Francesca Salvianti et al.
Background: Circulating tumor cells (CTCs) and circulating cell free DNA (ccfDNA) represent a liquid biopsy of a tumor allowing real time disease monitoring especially in advanced stages of cancer, but their analysis is t...
PCDH20 acts as a tumour-suppressor gene through the Wnt/β-catenin signalling pathway in hypopharyngeal squamous cell carcinoma [0.03%]
PCDH20通过Wnt/β-catenin信号通路在低咽鳞癌中发挥抑癌基因的作用
Zhitao Gong,Guohua Hu
Zhitao Gong
Background: Downregulation of PCDH20 is frequently involved in tumorigenesis of many cancers, but the role of PCDH20 protein in hypopharyngeal squamous cell carcinoma (HSCC) is still unknown. ...
Chhavi Gupta,Jian Su,Min Zhan et al.
Chhavi Gupta et al.
Background: Analysis of molecular changes in sputum may help diagnose lung cancer. Long non-coding RNAs (lncRNAs) play vital roles in various biological processes, and their dysregulations contribute to the development an...