ZHX2 inhibits proliferation and promotes apoptosis of human lung cancer cells through targeting p38MAPK pathway [0.03%]
ZHX2通过靶向p38MAPK通路抑制人肺癌细胞增殖并促进凋亡
Xudong Tian,Yadong Wang,Shuhai Li et al.
Xudong Tian et al.
Objective: To investigate the effect of ZHX2 on lung cancer cells proliferation and apoptosis. Materials and methods: The mRNA and prot...
Evaluating prognostic utility of preoperative Neutrophil to Lymphocyte Ratio and hsa-let-7g/c up-regulation in patients with urinary bladder cancer [0.03%]
评估预测膀胱癌患者预后的术前中性粒细胞与淋巴细胞比率和hsa-let-7g/c上调的效用
Nouha Setti Boubaker,Aymone Gurtner,Nesrine Trabelsi et al.
Nouha Setti Boubaker et al.
Background: Stratification and risk-evaluation of bladder cancer (BCa) patients are far-reached issues, especially for those with non muscle invasive disease. Thus, setting-up biomarkers, especially after resection of the...
Upregulation of ITGBL1 predicts poor prognosis and promotes chemoresistance in ovarian cancer [0.03%]
ITGBL1上调与卵巢癌化疗耐药及预后不良相关
Jiandong Song,Pengxia Yang,Jianjun Lu
Jiandong Song
Background: Ovarian cancer remains one of the most lethal malignancies in women and the unfavorable prognosis and frequent recurrence are mainly due to the chemoresistance. However, the main mechanism underlying chemoresi...
MicroRNA-125a-5p modulates radioresistance in LTEP-a2 non-small cell lung cancer cells by targeting SIRT7 [0.03%]
microRNA-125a-5p通过靶向SIRT7调节LTEP-a2非小细胞肺癌细胞的放射抵抗性
Chaonan Sun,Xue Zeng,Hong Guo et al.
Chaonan Sun et al.
Background: Micro(mi)RNAs are a series of 20-24 nt non-coding small-molecule single-stranded RNAs that are believed to be closely related to tumor occurrence, development and other biological processes. MicroRNA-125a modu...
Differences in cysteine peptidases-like activity in sera of patients with breast cancer [0.03%]
乳腺癌患者血清中半胱氨酸蛋白酶样活性的差异分析
Ewa Kilar,Maciej Siewiński,Lidia Hirnle et al.
Ewa Kilar et al.
Background: The key role in carcinogenesis with destruction of the extracellular matrix is played by proteases released by invasive cancer cells. Cysteine peptidases, such as cathepsin B and L, take an important role in c...
Diagnostic value of human epididymis protein 4 in malignant pleural effusion in lung cancer [0.03%]
人附睾蛋白4在肺癌恶性胸腔积液中的诊断价值
Min Lv,Fen Wang,Xiaoyan Wang et al.
Min Lv et al.
Objective: This study aimed to assess the diagnostic value of human epididymis protein 4 (HE4) in the pleural effusion of lung cancer patients. Methods: ...
TSHR rs2288496 associated with thyroid hormone and predict the occurrence of lymph node metastasis of papillary thyroid cancer [0.03%]
甲状腺激素受体基因多态性与甲状腺激素水平相关并可预测乳头状癌淋巴结转移的发生
Xuan Su,Li-Wen Lin,Jie-Ling Weng et al.
Xuan Su et al.
This study aimed to evaluate the association of potential functional tagging single nucleotide polymorphisms (tagSNPs) in BRAF and TSHR with papillary thyroid cancer (PTC). Two tagSNPs (rs6464149 and rs7810757) in BRAF and six tagSNPs (rs17...
Novel protein and immune response markers of human serous tubal intraepithelial carcinoma of the ovary [0.03%]
人类卵巢黏液性输卵管上皮内癌的新型蛋白和免疫反应标志物
Dmitriy W Gutkin,Michael R Shurin,Mounia Alaoui El Azher et al.
Dmitriy W Gutkin et al.
Ovarian cancer is the leading cause of death among gynecologic diseases in the USA and Europe. High-grade serous carcinoma (HGSC) of the ovary, the most aggressive type of ovarian cancer, is typically diagnosed at advanced stages when the 5...
Preoperative C-reactive protein-to-albumin ratio predicts anastomotic leak in elderly patients after curative colorectal surgery [0.03%]
术前C反应蛋白-白蛋白比值可预测老年人结直肠癌根治术后吻合口漏风险
Yongming Yu,Zhou Wu,Zhonglei Shen et al.
Yongming Yu et al.
Background: Anastomotic leak (AL), as one of the most devastating complications, is the leading cause of mortality in colorectal cancer (CRC) patients after resection. This study was aimed to investigate potential risk fa...
Deep learning-based model for predicting progression in patients with head and neck squamous cell carcinoma [0.03%]
基于深度学习的预测头颈鳞状细胞癌患者疾病发展的模型
Zhen Zhao,Yingli Li,Yuanqing Wu et al.
Zhen Zhao et al.
Purpose: This study endeavors to build a deep learning (DL)-based model for predicting disease progression in head and neck squamous cell carcinoma (HNSCC) patients by integrating multi-omics data. ...