Downregulation of serum exosomal miR-216b predicts unfavorable prognosis in patients with non-small cell lung cancer [0.03%]
血清外泌体miR-216b下调预测非小细胞肺癌患者预后不良
Wenqi Liu,Jing Liu,Qiangqiang Zhang et al.
Wenqi Liu et al.
Background: Increasing evidence have shown that miRNAs play an important role in the development and progression of non-small cell lung cancer (NSCLC). Ob...
Overexpression of miR-425-5p is associated with poor prognosis and tumor progression in non-small cell lung cancer [0.03%]
miR-425-5p过表达与非小细胞肺癌预后不良和肿瘤进展相关性研究
Yongxing Fu,Yuanyuan Li,Xiaoyan Wang et al.
Yongxing Fu et al.
Background: MicroRNA-425-5p (miR-425-5p) has been investigated in some human cancers, but the understanding of its clinical and functional roles in non-small cell lung cancer (NSCLC) remains poor. ...
MARCKS protein overexpression is associated with poor prognosis in male breast cancer [0.03%]
MARCKS蛋白过表达与男性乳腺癌预后不良相关
Maroua Manai,Syrine Abdeljaoued,Aïda Goucha et al.
Maroua Manai et al.
Background: Male breast cancer (MBC) is a rare and aggressive disease. Thus, identification of new therapeutic targets is crucial. Objective: ...
MiR-155 targeting FoxO3a regulates oral cancer cell proliferation, apoptosis, and DDP resistance through targeting FoxO3a [0.03%]
MiR-155通过靶向FoxO3a调节口腔癌细胞增殖、凋亡及顺铂耐药性
Xiaoting Li,Kun Liu,Wei Zhou et al.
Xiaoting Li et al.
FoxO3a is a well-defined tumor suppressor gene in the forkhead transcription factor O subfamily (FoxO), and its reduction is related to the occurrence of various tumors. It was found that the expression of miR-155 is abnormally elevated in ...
Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma [0.03%]
Apo10和TKTL1生物标志物：单核细胞抗原检出（EDIM）作为肝内胆管癌、胰腺癌及结直肠癌的新诊断方法
S Saman,M J Stagno,S W Warmann et al.
S Saman et al.
Objective: The EDIM (Epitope detection in monocytes) blood test is based on two biomarkers Apo10 and TKTL1. Apo10 is responsible for cell proliferation and resistance to apoptosis. TKTL1 plays a major role in anaerobic gl...
Emerging role of secreted miR-210-3p as potential biomarker for clear cell Renal Cell Carcinoma metastasis [0.03%]
分泌miR-210-3p作为透明细胞肾细胞癌转移潜在生物标志物的作用越来越重要
Vincenzo Petrozza,Manuela Costantini,Claudia Tito et al.
Vincenzo Petrozza et al.
Background: MicroRNAs (miRNAs) are emerging as promising molecules in the diagnosis, prognosis and treatment of urological tumours. Recently, our group performed two independent studies highlighting that miR-210-3p may be...
Circulating natural antibodies against 3'-sialyllactose complement the diagnostic performance of CA19-9 for the early detection of pancreatic ductal adenocarcinoma [0.03%]
循环中的抗3'-神经节苷脂抗体可补充CA19-9用于早期检测胰腺导管腺癌的诊断性能
Keita Yamada,Kiyoshi Higashi,Hirohisa Nagahori et al.
Keita Yamada et al.
Background: Pancreatic ductal adenocarcinoma is a devastating malignancy with an extremely poor prognosis. Although the most widely used biomarker for pancreatic cancer is carbohydrate antigen CA19-9, it is elevated mainl...
FHIT and C-MYC expression in cervical histology and cytology as biomarkers for detecting high-grade intraepithelial neoplasia in human papillomavirus-positive women [0.03%]
FHIT和C-MYC在人乳头瘤病毒阳性女性宫颈细胞学及组织病理中的表达：作为检测高级别上皮内瘤变生物标志物的研究
Fan Yang,Zifeng Cui,Yuandong Liao et al.
Fan Yang et al.
Background: The current cervical cancer screening strategies based on Papanicolaou (Pap) and Human papillomavirus (HPV) tests receive great achievement but still exhibit many limitations in clinical practice. Exploring ne...
Integrative analysis of gene alterations and immunoexpression profiles of cell cycle checkpoints in oral squamous cell carcinoma [0.03%]
整合基因改变和细胞周期检点免疫表达谱分析在口腔鳞状细胞癌中的应用
Mario Pérez-Sayáns,Cintia M Chamorro-Petronacci,Alejandro I Lorenzo-Pouso et al.
Mario Pérez-Sayáns et al.
Background: Oral squamous cell carcinoma (OSCC) represents 95% of all cancers of the head and neck region. The five-year survival rate of OSCC patients is about 60% and has not gone throw significant improvements despite ...
Long noncoding RNA HAND2-AS1 restrains proliferation and metastasis of breast cancer cells through sponging miR-1275 and promoting SOX7 [0.03%]
长链非编码RNA HAND2-AS1通过吸附miR-1275和促进SOX7来抑制乳腺癌细胞的增殖和转移
Yumei Wang,Xinglong Cai
Yumei Wang
Background: Breast cancer has become a major threat to women's physical and mental health. Many long noncoding RNAs (lncRNAs) have been reported to exert effect in the progression of breast cancer. However, the regulatory...