Low OCEL1 expression is associated with poor prognosis in human non-small cell lung cancer [0.03%]
OCEL1低表达与人类非小细胞肺癌不良预后相关
Mingming Deng,Zhe Zhang,Bofang Liu et al.
Mingming Deng et al.
Background: Occludin/ELL domain containing 1 (OCEL1) is a novel discovered protein with its molecular functions remaining unknown and its role in lung cancer has not been directly explored. ...
Survival prediction for patients with lung adenocarcinoma: A prognostic risk model based on gene mutations [0.03%]
基于基因突变的肺腺癌患者生存预测模型及预后风险评估
Hua Geng,Shixiong Li,Yixian Guo et al.
Hua Geng et al.
Background: Lung adenocarcinoma is the most common type of lung cancer, and it is one of the most aggressive and rapidly fatal tumor types. Objective: ...
Evaluation of paraneoplastic antigens reveals TRIM21 autoantibodies as biomarker for early detection of ovarian cancer in combination with autoantibodies to NY-ESO-1 and TP53 [0.03%]
评估肿瘤相关抗原发现TRIM21自身抗体与NY-ESO-1和TP53自身抗体联合用于卵巢癌早期检测的生物标志物价值
Laura C Hurley,Nancy K Levin,Madhumita Chatterjee et al.
Laura C Hurley et al.
Background: The majority of ovarian cancer cases are diagnosed at an advanced stage with poor prognosis. This study evaluates autoantibodies against tumor antigens to identify candidate biomarkers for early detection of o...
Identification of a novel microRNA profile including miR-106b, miR-17, miR-20b, miR-18a and miR-93 in the metastasis of nasopharyngeal carcinoma [0.03%]
鼻咽癌转移的新型微小核糖核酸(miR-106b、miR-17、miR-20b、miR-18a和miR-93)谱系的鉴定
Wei Zhou,Aoshuang Chang,Houyu Zhao et al.
Wei Zhou et al.
Background: Metastasis often leads to poor prognosis in nasopharyngeal carcinoma (NPC) patients. Evidence has indicated the important roles of microRNA (miRNA) in cancer metastasis. The aim of this study was to identify a...
The role of vesicular overexpressed in cancer pro-survival protein 1 in hepatocellular carcinoma proliferation [0.03%]
肝癌细胞增殖中囊泡过表达的癌症促生存蛋白1的作用研究
Zheping Fang,Linjun Wu,Haojiang Dai et al.
Zheping Fang et al.
Background: Recently, hepatocellular carcinoma (HCC) has been ranked as the second leading cause of cancer-associated death. However, the underlying molecular mechanisms of HCC progression remain unclear. Vesicular overex...
S Melloul,J-F Mosnier,J Masliah-Planchon et al.
S Melloul et al.
SMARCB1 is a tumor suppressor gene, which is part of SWI/SNF complex involved in transcriptional regulation. Recently, loss of SMARCB1 expression has been reported in gastrointestinal carcinomas. Our purpose was to evaluate the incidence an...
Novel somatic alterations underlie Chinese papillary thyroid carcinoma [0.03%]
新颖的体细胞突变在中国乳头状甲状腺癌中占重要地位
Chuanjia Yang,Weixue Xu,Jian Gong et al.
Chuanjia Yang et al.
To characterize the somatic alterations of papillary thyroid carcinomas (PTC) in Chinese patients, we performed the next-generation-sequencing (NGS) study of the tumor-normal pairs of DNA and RNA samples extracted from 16 Chinese PTC patien...
Low serum exosomal miR-484 expression predicts unfavorable prognosis in ovarian cancer [0.03%]
血清外泌体miR-484表达降低预测卵巢癌预后不良
Weijia Zhang,Xiaoyan Su,Shuang Li et al.
Weijia Zhang et al.
Background: Ovarian cancer (OC) is one of the most common malignancy worldwide. Emerging evidences have demonstrated that microRNAs (miRNAs) play an important role in regulating the initiation and development of OC. ...
STAT3 signaling statuses determine the fate of resveratrol-treated anaplastic thyroid cancer cells [0.03%]
转录因子STAT3决定白藜芦醇对分化型与未分化甲状腺癌作用结局
Jiao Wu,Yi-Tian Li,Xiao-Ting Tian et al.
Jiao Wu et al.
Backgrounds: Anaplastic thyroid cancer/ATC is highly lethal malignancy without reliable chemotherapeutic drug. Resveratrol possesses anti-ATC activities but encounters resistance in some cases due to certain unknown reaso...
METCAM/MUC18 is a new early diagnostic biomarker for the malignant potential of prostate cancer: Validation with Western blot method, enzyme-linked immunosorbent assay and lateral flow immunoassay [0.03%]
METCAM/MUC18是新的早期前列腺癌恶性潜能诊断标志物：与Western Blot、ELISA和胶体金试纸条法验证研究
Yuan-Hung Pong,Yann-Rong Su,Hsing-Wen Lo et al.
Yuan-Hung Pong et al.
Background: METCAM/MUC18 expression was increased with the malignant progression of prostate cancer and also a bona fide metastatic gene, capable of initiating and driving the metastasis of a non-metastatic human prostate...