A five-gene signature derived from m6A regulators to improve prognosis prediction of neuroblastoma [0.03%]
基于m垂直线6A调控因子的五基因谱型用于改善神经母细胞瘤预后预测
Zhichao Wang,Huiyan Cheng,Huali Xu et al.
Zhichao Wang et al.
Background and objective: N6-methyladenosine (m6a) is the most abundant form of methylated modification in eukaryotic mRNA. However, the role of m6A-related genes in neuroblastoma (NB), one of the most common paediatric m...
Plasma exosome-derived microRNA-532 as a novel predictor for acute myeloid leukemia [0.03%]
血浆外泌体衍生的微小核糖核酸-532作为急性髓系白血病的新预测标志物研究
Xia Lin,Qing Ling,Yunfei Lv et al.
Xia Lin et al.
Background: The interest in plasma biomarkers has increased recently. Plasma exosome-derived microRNA-532 is aberrantly expressed in a variety of human cancers and has the prognostic value in many solid tumors. However, t...
LGR4 overexpression is associated with clinical parameters and poor prognosis of serous ovarian cancer [0.03%]
LGR4过表达与浆液性卵巢癌的临床参数及不良预后相关
Zhaoyang Zeng,Na Ji,Juanjuan Yi et al.
Zhaoyang Zeng et al.
Objective: LGR4 expression in serous ovarian cancer paraffin-embedded tissues and fresh tissues were investigated, and its expression associated with clinicopathological parameters and prognosis in serous ovarian cancer w...
miR-654-3p predicts the prognosis of hepatocellular carcinoma and inhibits the proliferation, migration, and invasion of cancer cells [0.03%]
miR-654-3p预测肝癌预后并抑制肝癌细胞增殖、迁移和侵袭
Junsheng Yang,Zhen Zhang,Shaoping Chen et al.
Junsheng Yang et al.
Background: Increasing evidence reveals that aberrant microRNAs (miRNAs) expression play a crucial role in the tumorigenesis of cancers, including hepatocellular carcinoma (HCC), whereas the role of miR-654-3p in HCC rema...
Association analyses of a genetic variant in long non-coding RNA MEG3 with breast cancer susceptibility and serum MEG3 expression level in the Egyptian population [0.03%]
埃及人群中长链非编码RNA MEG3基因变异与乳腺癌易感性和血清MEG3表达量的关联分析
Marwa A Ali,Olfat G Shaker,Mohammed Alazrak et al.
Marwa A Ali et al.
Background: LncRNA MEG3 rs7158663 has been shown to confer cancer susceptibility, maybe through altering its gene expression level. Objective: ...
Circulating cell-free DNA variables as marker of ovarian cancer patients: A pilot study [0.03%]
循环细胞游离DNA变量可作为卵巢癌患者标志物的初步研究
Srdjan Stamenkovic,Jie Cheng,Harald Surowy et al.
Srdjan Stamenkovic et al.
Background: Minimal invasive blood-based molecular markers are evaluated as promising biomarkers in malignant diseases these days. Objective: ...
Observational Study
Cancer biomarkers : section A of Disease markers. 2020;28(2):159-167. DOI:10.3233/CBM-191018 2020
Elina Kaikkonen,Aliisa Takala,Juha-Pekka Pursiheimo et al.
Elina Kaikkonen et al.
Background: Elevated Anoctamin 7 (ANO7) expression is associated with poor survival in prostate cancer patients. Objective: The aim was...
LINC00467 knockdown repressed cell proliferation but stimulated cell apoptosis in glioblastoma via miR-339-3p/IP6K2 axis [0.03%]
LINC00467通过miR-339-3p/IP6K2轴在胶质母细胞瘤中抑制增殖并促进凋亡
Rui Liang,Youjia Tang
Rui Liang
Background: Glioma is considered to be one of the most common and lethal malignant brain tumors, accounting for 40% to 50% of brain tumors. Long non-coding RNAs (lncRNAs) have been widely proved to play an irreplaceable r...
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer [0.03%]
ARHGDIB在乳腺癌中作用的系统研究
Xiaonan Wang,Xiaomin Bi,Xing Huang et al.
Xiaonan Wang et al.
Background: ARHGDIB, a Rho GDP dissociation inhibitor protein, has been reported playing critical roles in regulation of multiple biological responses. However, whether ARHGDIB serves as a valuable biomarker in cancer is ...
Utility of urinary ctDNA to monitoring minimal residual disease in early breast cancer patients [0.03%]
尿液ctDNA用于早期乳腺癌患者最小残余病监测的价值
Gege Guan,Yuehua Wang,Qiushi Sun et al.
Gege Guan et al.
Background: Cancer recurrence for patients with early breast cancer is significant. Patients will benefit from more non-invasive modes of monitoring and we aim to study the feasibility of urinary circulating tumor DNA (ct...