LINC00174 is a favorable prognostic biomarker in glioblastoma via promoting proliferative phenotype [0.03%]
长链非编码RNA LINC00174通过促进增殖表型成为胶质母细胞瘤的有利预后生物标志物
Zheng Wang,Qiangwei Wang,Zhaoshi Bao et al.
Zheng Wang et al.
Objective: To investigate the expression pattern, prognostic value and biological functional of LINC00174 in glioma. Methods: In total,...
Immunosuppressive receptor LILRB1 acts as a potential regulator in hepatocellular carcinoma by integrating with SHP1 [0.03%]
免疫抑制受体LILRB1通过与SHP1整合在肝癌中发挥潜在调控作用
Jianghong Cheng,Jing Luan,Peng Chen et al.
Jianghong Cheng et al.
Background: Immunosuppressive receptor LILRB1 regulates tumors progression by transducing immune inhibitory signals via intracellular immunoreceptor tyrosine-based inhibitory motifs. However, its role in Hepatocellular Ca...
Alterations of regulatory factors and DNA methylation pattern in thyroid cancer [0.03%]
甲状腺癌中调控因子和DNA甲基化模式的改变
Iulia V Iancu,Anca Botezatu,Adriana Plesa et al.
Iulia V Iancu et al.
Purpose: DNA methylation plays an important role in thyroid oncogenesis. The aim of this study was to investigate the connection between global and local DNA methylation status and to establish the levels of important DNA...
5-aminolevulinic-acid-mediated sonodynamic therapy improves the prognosis of melanoma by inhibiting survivin expression [0.03%]
基于血红素前体5-氨基乙酰丙酸的声动力疗法通过抑制存活蛋白提高黑色素瘤治疗效果
Haixia Fan,Zheng Hu,Shan Wang et al.
Haixia Fan et al.
Background: This study aimed to evaluate the relationship between survivin expression and melanoma after 5-aminolevulinic acid (5-ALA)-mediated sonodynamic therapy. ...
Circular RNA circ_0000337 contributes to osteosarcoma via the miR-4458/BACH1 pathway [0.03%]
环状RNA circ_0000337通过miR-4458/BACH1途径促进骨肉瘤发展
Yuan Fang,Fang Long
Yuan Fang
Background: As the most prevalent primary bone malignancy in children and adolescents, osteosarcoma (OS) has attracted increasing attention. The role of circRNAs in OS has been elucidated in some reports, but many circRNA...
Huifeng Cao,Liang Cheng,Junjuan Yu et al.
Huifeng Cao et al.
Objective: To identify the mRNAs associated with bladder cancer (BC) recurrence. Methods: The transcription profile of GSE31684 includi...
Expression of FOXM1 and Aurora-A predicts prognosis and sorafenib efficacy in patients with hepatocellular carcinoma [0.03%]
FOXM1和Aurora-A的表达预测肝细胞癌患者的预后及索拉非尼疗效
Wen-Lung Su,Shih-Chang Chuang,Yu-Chu Wang et al.
Wen-Lung Su et al.
Background: Effective prognostic biomarkers and powerful target-therapeutic drugs are needed for improving the treatment of Hepatocellular carcinoma (HCC). ...
CD133 expressionand clinicopathologic significance in benign and malignant breast lesions [0.03%]
CD133在乳腺良恶性疾病中的表达及临床病理意义分析
Ting Ting Liu,Xue Feng Li,Li Wang et al.
Ting Ting Liu et al.
Background/objective: CD133 is the molecular marker of normal stem cells and progenitor cells and also confirmed as a marker for cancer stem cells in various tumors. The aim of this study is to examine the expression of C...
Circulating cell-free DNA (cfDNA) levels in BRCA1 and BRCA2 mutation carriers: A preliminary study [0.03%]
BRCA1和BRCA2基因突变携带者循环细胞游离DNA（cfDNA）水平的初步研究
Amos Douvdevani,Rinat Bernstein-Molho,Keren Asraf et al.
Amos Douvdevani et al.
Background: Female carriers of BRCA1 or BRCA2 germline mutations are at a substantially increased risk for developing breast and ovarian cancer. The lack of effective early detection schemes for ovarian cancer, mandate su...
Arsenic trioxide-induced upregulation of miR-1294 suppresses tumor growth in hepatocellular carcinoma by targeting TEAD1 and PIM1 [0.03%]
砷酸盐通过上调miR-1294抑制肝癌细胞中TEAD1和PIM1的表达从而抑制肿瘤生长
Xiaoniao Cai,Leilei Yu,Zhen Chen et al.
Xiaoniao Cai et al.
Recently, Arsenic trioxide (ATO) has been reported as an efficient drug for suppression of cancer cell growth. Existing studies revealed the extensive involvement of microRNAs (miRNAs) in initiation and development of hepatocellular carcino...