Circ_0000376 enhances the proliferation, metastasis, and chemoresistance of NSCLC cells via repressing miR-384 [0.03%]
circ_0000376通过抑制miR-384促进非小细胞肺癌细胞增殖、转移和耐药性
Hui Sun,Yi Chen,Yue-Yu Fang et al.
Hui Sun et al.
Background: Non-small cell lung cancer (NSCLC) is the most common cancer worldwide. Circular RNAs (circRNAs) are recently identified as important gene regulators with critical roles in cancer biology. In this study, we fo...
Serum Matrix metalloproteinase-9 (MMP-9) can help identify patients with papillary thyroid cancer at high risk of persistent disease: Value and limitations of a potential marker of neoplasia [0.03%]
血清基质金属蛋白酶-9(MMP-9)可帮助识别患分化型乳头状甲状腺癌高危患者：潜在肿瘤标志物的价值及局限性
Ruxandra Dobrescu,Catalina Picu,Andra Caragheorgheopol et al.
Ruxandra Dobrescu et al.
Background: Matrix metalloproteinase-9 (MMP-9) is an important mediator of invasion and metastasis in neoplasia. In thyroid cancer expression levels correlate with aggressiveness but data on peripheral MMP-9 levels are le...
Observational Study
Cancer biomarkers : section A of Disease markers. 2020;29(3):337-346. DOI:10.3233/CBM-190609 2020
MiR-196a promoted cell migration, invasion and the epithelial-mesenchymal transition by targeting HOXA5 in osteosarcoma [0.03%]
微RNA-196a通过靶向HOXA5促进成骨肉瘤细胞迁移、侵袭和上皮间充质转化
Xiaoli Wang,Lili Zhang,Xingfeng Zhang et al.
Xiaoli Wang et al.
Introduction: Osteosarcoma (OS), aggressive neoplasms of the bone, is the most common primary bone cancer in children. MiR-196a usually low expressed in several tumors and its functions in osteosarcoma still unclear. ...
Sun Il Kim,Ja Seung Koo
Sun Il Kim
Background: Phyllodes tumor (PT) is a rare tumor showing various malignant potential. The histological grade of PT is related to clinical outcome, but its relationship between gaining of malignant potential and underlying...
Mammalian SIRT4 is a tumor suppressor of clear cell renal cell carcinoma by inhibiting cancer proliferation, migration and invasion [0.03%]
哺乳动物SIRT4通过抑制癌细胞增殖、迁移和侵袭发挥透明细胞肾细胞癌的肿瘤抑制作用
Changming Wang,Chiyuan Piao,Junlong Liu et al.
Changming Wang et al.
Objective: Sirtuins family are defined as class III histone deacetylases (HDACs). Recently, mammalian silent information regulator two 4 (SIRT4) has been reported to be a tumor suppressor gene in multiple cancers. The obj...
Carboxypeptidase E down-regulation regulates transcriptional and epigenetic profiles in pancreatic cancer cell line: A network analysis [0.03%]
羧肽酶E下调通过网络分析调节胰腺癌细胞系的转录和表观遗传特征
Zhile Bai,Mengyu Feng,Yang Du et al.
Zhile Bai et al.
Background: Pancreatic cancer is a malignant tumor and its incidence has increased in recent years. Carboxypeptidase E (CPE) is a prohormone/proneuropeptide processing enzyme that has been shown to be associated with tumo...
lncRNA GAS8-AS1 genetic alterations in papillary thyroid carcinoma and their clinical significance [0.03%]
GAS8-AS1基因变异在乳头状甲状腺癌中的临床意义研究
Da-Lei Zhou,Qing Liu,Bo-Heng Xu et al.
Da-Lei Zhou et al.
The long non-coding RNA (lncRNA) GAS8-AS1 is the second-most frequently altered gene, following the BRAF gene, in papillary thyroid carcinoma (PTC). We aimed to study the specificity and significance of genetic alterations in GAS8-AS1 in PT...
Observational Study
Cancer biomarkers : section A of Disease markers. 2020;29(2):255-264. DOI:10.3233/CBM-191071 2020
LncRNA NEAT1 accelerates breast cancer progression through regulating miR-410-3p/ CCND1 axis [0.03%]
长链非编码RNA NEAT1通过调节miR-410-3P/CCND1轴促进乳腺癌进展
Xuan Liu,Weirong Yao,Haiwei Xiong et al.
Xuan Liu et al.
Background: Breast cancer is the most common malignant tumor and usually occurs in women. Studies have shown that lncRNA nuclear enriched abundant transcript 1 (NEAT1) contributes to breast cancer progression. This study ...
LRP4 promotes migration and invasion of gastric cancer under the regulation of microRNA-140-5p [0.03%]
microRNA-140-5p通过靶向LRP4促进胃癌迁移和侵袭
Zhijun Mao,Zhen Wang,Shiping Zhang et al.
Zhijun Mao et al.
Background: Low-density lipoprotein receptor-related protein 4 (LRP4) has been reported to be implicated in multiple types of cancers. However, the significance of LRP4 in gastric cancer (GC) remains poorly elucidated. Th...
Nomogram based on pre-treatment inflammatory biomarkers predicting survival in patients with head and neck soft tissue sarcoma [0.03%]
基于术前炎症生物标志物的头颈部软组织肉瘤患者预后生存 nomogram预测模型
Linyan Chen,Hao Zeng,Ze Du et al.
Linyan Chen et al.
Background: Systemic inflammatory biomarkers reflect level of inflammatory response, which have been suggested as prognostic factors in cancer patients. O...