TGF-β downregulation overcomes gemcitabine resistance in oral squamous cell carcinoma [0.03%]
TGF-β下调可克服口腔鳞状细胞癌中的吉西他滨耐药性
Yun-Ze Xuan,Cheng-Ri Jin,Kang-Juan Yang
Yun-Ze Xuan
Objective: The aim of this study was to explore the mechanisms by which oral cancer acquires resistance to gemcitabine. Methods: Oral s...
Predictions of the dysregulated competing endogenous RNA signature involved in the progression of human lung adenocarcinoma [0.03%]
人类肺腺癌进展相关失调竞争性内源性RNA标志物的预测研究
Dan Yang,Yang He,Bo Wu et al.
Dan Yang et al.
Background: Lung adenocarcinoma (LUAD) is the most common histological subtype of lung cancer worldwide. Until now, the molecular mechanisms underlying LUAD progression have not been fully explained. This study aimed to c...
Distinct association of RUNX family expression with genetic alterations and clinical outcome in acute myeloid leukemia [0.03%]
RUNX家族在急性髓系白血病中的表达与遗传改变及临床预后的特异性关联研究
Yangli Zhao,Tingjuan Zhang,Yangjing Zhao et al.
Yangli Zhao et al.
Background: The runt-related transcription factor family (RUNXs) including RUNX1, RUNX2, and RUNX3 are key transcriptional regulators in normal hematopoiesis. RUNXs dysregulations caused by aberrant expression or mutation...
MicroRNA-629 promotes the tumorigenesis of non-small-cell lung cancer by targeting FOXO1 and activating PI3K/AKT pathway [0.03%]
microRNA-629通过靶向FOXO1和激活PI3K/AKT途径促进非小细胞肺癌的肿瘤发生
Lin Zhu,Yinan Chen,Jing Liu et al.
Lin Zhu et al.
Objective: MicroRNA-629 (miR-629) has been found to play an important role in the pathogenesis of human cancers. However, the function of miR-629 is still unknown in non-small-cell lung cancer (NSCLC). The purpose of this...
Observational Study
Cancer biomarkers : section A of Disease markers. 2020;29(3):347-357. DOI:10.3233/CBM-201685 2020
Isolation of extracellular vesicle with different precipitation-based methods exerts a tremendous impact on the biomarker analysis for clinical plasma samples [0.03%]
不同类型的沉淀法分离外泌体对临床血浆样本生物标志物分析影响巨大
Cheng Peng,Jizhuang Wang,Qiyuan Bao et al.
Cheng Peng et al.
Background: Extracellular vesicles(EVs) is an emerging approach of cancer liquid biopsy. Although the precipitation-based method with commercial kits has gained popularity as the second most commonly used technique, these...
Observational Study
Cancer biomarkers : section A of Disease markers. 2020;29(3):373-385. DOI:10.3233/CBM-201651 2020
TRIB3 promotes hepatocellular carcinoma growth and predicts poor prognosis [0.03%]
TRIB3促进肝癌细胞增殖并提示不良预后
Xiao-Jun Wang,Fei-Fei Li,Yi-Jing Zhang et al.
Xiao-Jun Wang et al.
Background: Tribbles pseudokinase 3 (TRIB3) is a member of the tribbles-related family, which is involved a lot of cellular processes and multiple cancers, such as breast cancer, colorectal cancer, renal cell carcinomas, ...
Observational Study
Cancer biomarkers : section A of Disease markers. 2020;29(3):307-315. DOI:10.3233/CBM-201577 2020
miR-199a-5p suppresses epithelial- mesenchymal-transition in anaplastic thyroid carcinoma cells via targeting Snail signals [0.03%]
微RNA-199a-5p通过靶向Snail信号抑制间变性甲状腺癌上皮间质转化效应
Fengyun Hao,Ya-Nan Bi,Lei Wang et al.
Fengyun Hao et al.
MicroRNAs (miRNAs) have been validated to play prominent roles in the occurrence and development of anaplastic thyroid carcinoma (ATC). miR-199a-5p was previously reported to act as a tumor suppressor or oncomiRNA in various types of cancer...
Observational Study
Cancer biomarkers : section A of Disease markers. 2020;29(3):317-326. DOI:10.3233/CBM-201518 2020
Identification of diagnostic and prognostic lncRNA biomarkers in oral squamous carcinoma by integrated analysis and machine learning [0.03%]
综合分析和机器学习在口腔鳞状细胞癌的诊断和预后长链非编码RNA生物标志物识别中的应用
Sen Yang,Yingshu Wang,Jun Ren et al.
Sen Yang et al.
Background: Patients with oral squamous carcinoma (OSCC) present difficulty in precise diagnosis and poor prognosis. Objective: We aime...
Pre-surgical level of von Willebrand factor as an evident indicator of breast cancer recurrence [0.03%]
术前血管性血友病因子作为乳腺癌复发的明显指标
Piotr Rhone,Elżbieta Zarychta,Kornel Bielawski et al.
Piotr Rhone et al.
Background: Endothelial and platelet activation as well as a disruption of haemostatic balance are crucial in cancer-dependent venous thromboembolism development. ...
Observational Study
Cancer biomarkers : section A of Disease markers. 2020;29(3):359-372. DOI:10.3233/CBM-191096 2020
Prognostic value of post-radiation serum squamous cell carcinoma antigen and primary tumor regression for cervical squamous cell carcinoma [0.03%]
放射治疗后鳞状细胞癌抗原与宫颈鳞癌主要肿瘤消退的预后价值
Quan Wan,Wangxiang Yan,Yonghong Liu et al.
Quan Wan et al.
Objective: In this study, we determined the prognostic values of magnetic resonance imaging (MRI)-based primary tumor regression and serum squamous cell carcinoma antigen (SSCC-Ag) levels 4 weeks after definitive radiothe...
Observational Study
Cancer biomarkers : section A of Disease markers. 2020;29(3):327-335. DOI:10.3233/CBM-190934 2020