Microbial biomarker development for detection and prognosis of early-stage non-small cell lung cancer [0.03%]
用于检测和预测早期非小细胞肺癌的微生物生物标志物的研究与发展
Fares Darawshy,Jun-Chieh J Tsay,Leopoldo N Segal et al.
Fares Darawshy et al.
Non-small cell lung cancer (NSCLC) remains the most common cause for cancer-related mortality despite advances in treatment. Early detection is crucial for improving patient outcomes, yet current diagnostic and prognostic molecular biomarke...
Exploring lipid metabolism-associated gene biomarkers and their regulatory mechanisms in nasopharyngeal carcinoma [0.03%]
鼻咽癌脂质代谢相关基因生物标志物及其调控机制的探究
Yiyi Liu,Yingying Xie,Yong Wang
Yiyi Liu
BackgroundNasopharyngeal carcinoma (NPC) is a neoplasm that arises from the mucosal lining of the nasopharynx. Recent investigations have underscored that reprogramming of lipid metabolism is a salient metabolic alteration in neoplastic cel...
Development and validation of a CT-based radiomics nomogram for predicting cervical lymph node metastasis in papillary thyroid carcinoma [0.03%]
基于CT的影像组学预测乳头状甲状腺癌中央区淋巴结转移的模型建立及验证
Fengyan Zhang,Jingjing Bai,Botao Liu et al.
Fengyan Zhang et al.
ObjectiveThis study aimed to develop and validate a radiomics nomogram based on 40 KeV images and iodine density maps derived from dual-layer spectral detector CT (DLSDCT) for predicting cervical lymph node (LN) metastasis in patients with ...
The relationship between serum levels of GRP78, GRP94, calnexin, and calreticulin and prognosis in patients with lung cancer [0.03%]
肺癌患者血清GRP78、GRP94、calnexin和calreticulin水平与预后的关系分析
Guntulu Ak,Selma Metintas,Hasan Veysi Gunes et al.
Guntulu Ak et al.
BackgroundTo determine the serum levels of endoplasmic reticulum (ER) chaperones, glucose-regulated protein 78 (GRP78), glucose-regulated protein 94 (GRP94), calnexin, and calreticulin in patients with lung cancer and in the control group a...
Prognosis of keratinizing squamous cell carcinoma of the female reproductive system: A retrospective study [0.03%]
女性生殖系统角化鳞状细胞癌的预后分析：一项回顾性研究
Ruiqing Chen,Hai Yu,Xinkai Zheng et al.
Ruiqing Chen et al.
Objective: The aim of this study was to compare the competing risk model with the Cox model to evaluate prognostic markers in females with keratinized squamous cell carcinoma of the reproductive system and to develop predictive models. Meth...
Evaluating the efficacy of PARP inhibitor in ARID1A-deficient colorectal cancer: A ex vivo study [0.03%]
ARID1A缺陷型结直肠癌中PARP抑制剂疗效的评估：一种体外研究方法
Rui Zong,Ping Zhou,Shaojie Qin et al.
Rui Zong et al.
ARID1A mutations are a common occurrence in colorectal cancer (CRC) cells, but clinical therapeutic options targeting this anomaly remain unavailable. The loss of ARID1A functionality compromises DNA damage repair processes, potentially cau...
Knockdown of HSF1 inhibits invasion, metastasis, and proliferation of endometrial carcinoma cells while promoting apoptosis [0.03%]
HSF1敲低抑制子宫内膜癌细胞侵袭、转移和增殖并促进其凋亡
Haixia Liu,Xiao Gu,Jinlai Meng et al.
Haixia Liu et al.
BackgroundHeat shock factor 1 (HSF1), the principal transcriptional regulator of cellular stress responses, has been exhibited to play a role in the progression of various human cancer types. However, the function of HSF1 in endometrial can...
CXCL1 and CXCL8: Reliable and feasible biomarkers differentiating intrapulmonary metastasis from multiple primary neoplasms in non-small cell lung cancers [0.03%]
CXC基序配体1和8鉴别非小细胞肺癌内肺转移与多原发肿瘤的可靠性和可行性的生物标志物研究
Ao Liu,Tianlin Sun,Tong Qiu et al.
Ao Liu et al.
ObjectiveIn NSCLC, the main approach to differentiate between intrapulmonary metastases (IPM) and multiple primary lung cancer (MPLC) is to integrate histopathological and genomic information. Here, we identified viable biomarkers that can ...
Serum Protein Profiling as theranostic biomarkers for Left- and Right-Sided Colon Cancer using Luminex® technology [0.03%]
采用Luminex技术研究血清蛋白作为左半结肠癌和右半结肠癌诊疗标志物的差异性
Amani Attia,Azza Habel,Weili Xu et al.
Amani Attia et al.
BackgroundGiven the differences between malignancies arising from different segments of the colon, specific theranostic biomarkers can be linked to either Right-sided (RCC) or Left-sided colon cancer (LCC).ObjectiveAnalysis of 65 serum prot...
Panax notoginseng improves the sensitivity of non-small cell lung cancer to cisplatin by inhibiting Akt signaling [0.03%]
三七通过抑制Akt信号通路增强非小细胞肺癌顺铂敏感性
Lizhen Pan,Dandan Zhang,Qiqi Shao et al.
Lizhen Pan et al.
BackgroundCisplatin (DDP) resistance is a major challenge in the management of non-small cell lung cancer (NSCLC). Panax notoginseng has anticancer effects on a variety of solid tumors, but data on NSCLC and DDP resistance are lacking.Objec...