Coiled-coil domain-containing protein-124 (Ccdc124) is a novel RNA binding factor up-regulated in endometrial, ovarian, and urinary bladder cancers [0.03%]
卷曲螺旋结构域含蛋白质124（CCDC124）是一种新型RNA结合因子并在子宫内膜癌、卵巢癌及膀胱癌中高表达
Özge Arslan,Neşe Karadağ Soylu,Pelin Telkoparan Akillilar et al.
Özge Arslan et al.
Background: Coiled-coil domain containing protein-124 (Ccdc124) is a putative mRNA-binding factor associated with cell division, and ribosome biology. Previous reports mentioned an up-regulation of CCDC124 gene in cancer,...
Implementation of clinical sequencing for molecular profiling in patients with advanced cancer [0.03%]
晚期癌症患者临床测序的实施及其分子分型作用
Tomoya Fukui,Kazuko Sakai,Jiichiro Sasaki et al.
Tomoya Fukui et al.
Background: The advancement of cancer genomics has allowed for multiplex gene assays using next-generation sequencing (NGS) to be practically implemented, however, a clinical practice system remains to be established. ...
Observational Study
Cancer biomarkers : section A of Disease markers. 2021;31(2):119-126. DOI:10.3233/CBM-200781 2021
Prognostic significance of preoperative systemic immune-inflammation index in combined hepatocellular-cholangiocarcinoma [0.03%]
术前系统免疫炎症指数对肝细胞癌合并胆管细胞癌的预后价值
Feng Zhang,Ke-Shu Hu,Shen-Xin Lu et al.
Feng Zhang et al.
Background: Inflammation-based prognostic scores have been increasingly used for prognosis prediction in malignant tumors. However, no existing study has comprehensively evaluated these scores in combined hepatocellular-c...
Homeobox-A13 acts as a functional prognostic and diagnostic biomarker via regulating P53 and Wnt signaling pathways in lung cancer [0.03%]
HOXA13通过调节P53和Wnt信号通路在肺癌中发挥功能性的预后和诊断生物标志物作用
Yang Wang,Bo He,Yan Dong et al.
Yang Wang et al.
Background: The prognosis of lung cancer patients is poor without useful prognostic and diagnostic biomarker. To search for novel prognostic and diagnostic markers, we previously found homeobox-A13 (HOXA13) as a promising...
RUNX2 promotes malignant progression in gastric cancer by regulating COL1A1 [0.03%]
RUNX2通过调控COL1A1促进胃癌恶性进展
Yanlei Li,Ran Sun,Xiulan Zhao et al.
Yanlei Li et al.
Background: Runt-related transcription factor 2 (RUNX2) is an important gene that has been implicated in the progression of human cancer. Aberrant expression of RUNX2 predicts gastric cancer (GC) metastasis. However, the ...
TRIB3 promotes proliferation, migration, and invasion of retinoblastoma cells by activating the AKT/mTOR signaling pathway [0.03%]
TRIB3通过激活AKT/mTOR信号通路促进视网膜母细胞瘤细胞的增殖、迁移和侵袭
Xian-Yi Bao,Ming Sun,Ting-Ting Peng et al.
Xian-Yi Bao et al.
Background: Tribbles pseudokinase 3 (TRIB3) is a member of the tribbles-related family, which has been determined in various cancers, including renal cell carcinoma, acute promyelocytic leukemia, colorectal cancer, endome...
SPARC regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma [0.03%]
SPARC通过调节索拉非尼诱导的铁死亡抑制肝癌细胞进展
Hong-Wei Hua,Hao-Sheng Jiang,Ling Jia et al.
Hong-Wei Hua et al.
Background: Secreted protein acidic and rich in cysteine (SPARC) is implicated in cancer progression, but its role and associated molecular mechanism in the sorafenib sensitivity of hepatocellular carcinoma cells (HCC) re...
High expression of CPNE5 and CPNE9 predicts positive prognosis in multiple myeloma [0.03%]
CPNE5和CPNE9高表达预示多发性骨髓瘤的良好预后
Pei Zhu,Tingting Qian,Chaozeng Si et al.
Pei Zhu et al.
Background: CPNEs are significant biomarkers which can affect the progression and prognosis of various tumor diseases. However, the prognosis role of CPNEs in multiple myeloma (MM) is still unclear. ...
Molecular mechanisms, immune cell infiltration, and potential drugs for prostate cancer [0.03%]
前列腺癌的分子机制、免疫细胞浸润及潜在药物研究
Yunkun Yan,Xingning Mao,Qingyun Zhang et al.
Yunkun Yan et al.
Background: The molecular mechanisms involved in the prostate cancer and their relationship with immune cell infiltration are not fully understood. The prostate cancer patients undergoing standard androgen deprivation the...
Overexpression of BAMBI and SMAD7 impacts prognosis of acute myeloid leukemia patients: A potential TERT non-canonical role [0.03%]
BAMBI和SMAD7过表达影响急性髓系白血病患者的预后：TERT非经典作用的潜在可能性
Miral Magdy Shehata,Al-Aliaa Mohamed Sallam,Mary Gamal Naguib et al.
Miral Magdy Shehata et al.
Background: Bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and mothers against decapentaplegic homolog 7 (SMAD7) are important transforming growth factor-β (TGF-β) signaling antagonists, however...