The predictive potential of Neuronatin for neoadjuvant chemotherapy of breast cancer [0.03%]
神经肽N预测乳腺癌新辅助化疗的潜力
Willi Pieper,Atanas Ignatov,Thomas Kalinski et al.
Willi Pieper et al.
Background: Neuronatin (NNAT) determined by immunohistochemistry is a negative prognostic biomarker for breast cancer, independent of the major clinicopathological markers. ...
High FAS expression correlates with a better prognosis and efficacy of taxanes and target regents in breast cancer [0.03%]
FAS高表达与乳腺癌预后较好和紫衫类及靶向药物疗效好的临床相关性研究
Yi Zhang,Xuan Shao,Chenyi Gao et al.
Yi Zhang et al.
Background: FAS can serve as both an oncogene and a suppresser in different malignancies, and the prognostic value of FAS remains controversial. Methods: ...
Profile of sphingolipid-related genes and its association with prognosis highlights sphingolipid metabolism in oral cancer [0.03%]
与预后相关的鞘脂相关基因谱型强调了口腔癌中的鞘脂代谢作用
Gabriel da Silva,Leandro Luongo de Matos,Luiz Paulo Kowalski et al.
Gabriel da Silva et al.
Background: Sphingolipids are bioactive lipids that play a role in cancer development. However, the clinical role of sphingolipid (SPL)-related genes in oral cancer (OC) remains not fully understood. ...
Quantitative analysis of KLF4 and SOX2 expression in oral carcinomas reveals independent association with oral tongue subsite location and histological grade [0.03%]
KLF4和SOX2在口腔鳞癌中的定量分析及其与解剖位置和组织学分级的独立相关性研究
María Luisa Paparella,Dario Martin Ferri,Krissya María Villegas et al.
María Luisa Paparella et al.
Background: Stemness factors associated with tumorigenesis in different types of cancers have not been specifically studied in oral tongue SCC (OTSSC). Here, we aimed to quantify expression levels and distribution of KLF4...
Diagnostic value of oncofetal miRNAs in cancers: A comprehensive analysis of circulating miRNAs in pan-cancers and UCB [0.03%]
外泌体来源的癌胚miRNA作为癌症诊断标志物的泛癌分析及尿液中膀胱癌诊断标志物筛选研究
Xin Zhou,Cheng Liu,Yin Yin et al.
Xin Zhou et al.
Background: Circulating miRNAs are promising biomarkers for detection of various cancers. As a "developmental" disorder, cancer showed great similarities with embryos. ...
Prognostic and predictive significance of the tumor microenvironment in hepatocellular carcinoma [0.03%]
肝细胞癌肿瘤微环境的预后和预测意义
Jibing Liu,Shuwen Kuang,Yiling Zheng et al.
Jibing Liu et al.
Background: Identification of molecular markers that reflect the characteristics of the tumor microenvironment (TME) may be beneficial to predict the prognosis of post-operative hepatocellular carcinoma (HCC) patients. ...
Circulating microRNA-762 upregulation in colorectal cancer may be accompanied by Wnt-1/β-catenin signaling [0.03%]
循环microRNA-762在结直肠癌中升高可能伴随Wnt-1/β-catenin信号通路活化
Peng-Sheng Lai,Wei-Min Chang,Ying-Yin Chen et al.
Peng-Sheng Lai et al.
Colorectal cancer (CRC) has become the third most common cause of cancer-related deaths. CRC occurs because of abnormal growth of cells that can invade other tissues and cause distant metastases. Researchers have suggested that aberrant mic...
The expression and diagnostic value of serum levels of EphA2 and VEGF-A in patients with colorectal cancer [0.03%]
EphA2和VEGF-A的血清表达及诊断价值的研究
Ganbiao Wang,Yigao Wang,Xiaodong Yang et al.
Ganbiao Wang et al.
Background: Several molecules are highly expressed in the serum of cancer patients, and can be used as serological markers. This approach has become one of the important auxiliary diagnostic methods for cancer. ...
Genetic polymorphisms of Cathepsin B are associated with gastric cancer risk and prognosis in a Chinese population [0.03%]
中国人溶酶体组织蛋白酶B基因多态性与胃癌易感性和预后的关系研究
Xiang Ma,Younan Wang,Hao Fan et al.
Xiang Ma et al.
Background: Genetic polymorphisms are believed to represent a key aspect of predisposition to gastric cancer (GC). Therefore, considering the important role of Cathepsin B (CTSB) in promoting cancer onset and development,...
Observational Study
Cancer biomarkers : section A of Disease markers. 2021;32(2):189-198. DOI:10.3233/CBM-203208 2021
Impact of detecting plasma EGFR mutations with ultrasensitive liquid biopsy in outcomes of NSCLC patients treated with first- or second-generation EGFR-TKIs [0.03%]
超敏感液体活检检测血浆EGFR突变对第一代和第二代表皮生长因子受体酪氨酸激酶抑制剂治疗非小细胞肺癌患者预后的影响分析
Oscar Arrieta,Juan-Manuel Hernandez-Martinez,Edgar Montes-Servín et al.
Oscar Arrieta et al.
Background: Few trials have evaluated the utility of liquid biopsies to detect epidermal growth factor receptor mutations (EGFRm) at the time of response evaluation and its association with the clinical characteristics an...
Observational Study
Cancer biomarkers : section A of Disease markers. 2021;32(2):123-135. DOI:10.3233/CBM-203164 2021