LncRNA BCAR4 expression predicts the clinical response to neoadjuvant chemotherapy in patients with locally advanced breast cancer [0.03%]
BCAR4长链非编码RNA表达预测局部晚期乳腺癌新辅助化疗的疗效
Feng-Jiao Gan,Yi Li,Meng-Xi Xu et al.
Feng-Jiao Gan et al.
Background: Neoadjuvant chemotherapy (NAC) is an important treatment for locally advanced breast cancer (LABC). However, there are no effective biomarkers to predict the efficacy. Therefore, there is an urgent need for ne...
HPV-associated penile cancer: Impact of copy number alterations in miRNA/mRNA interactions and potential druggable targets [0.03%]
人乳头瘤病毒相关阴茎癌：miRNA/mRNA相互作用的拷贝数改变的影响及潜在治疗靶点
Jenilson da Silva,Leudivan Nogueira,Ronald Coelho et al.
Jenilson da Silva et al.
Background: Penile cancer (PeCa) is a rare disease, but its incidence has increased worldwide, mostly in HPV+ patients. Nevertheless, there is still no targeted treatment for this carcinoma. ...
Observational Study
Cancer biomarkers : section A of Disease markers. 2021;32(2):147-160. DOI:10.3233/CBM-210035 2021
POM121 promotes proliferation and metastasis in non-small-cell lung cancer through TGF-β/SMAD and PI3K/AKT pathways [0.03%]
POM121通过TGF-β / SMAD和PI3K / AKT途径促进非小细胞肺癌的增殖和转移
Lirong Guan,Lingli Zhang,Tengqi Wang et al.
Lirong Guan et al.
Background: Nuclear pore membrane protein 121 (POM121) is a novel biomarker involved in tumorigenesis and metastasis. However, little is known about the role of POM121 in non-small-cell lung cancer (NSCLC). ...
Screening of cervical cancer-related hub genes based on comprehensive bioinformatics analysis [0.03%]
基于综合生物信息学分析的宫颈癌相关关键基因筛查
Simei Tu,Hao Zhang,Xiaocheng Yang et al.
Simei Tu et al.
Background: Since the molecular mechanisms of cervical cancer (CC) have not been completely discovered, it is of great significance to identify the hub genes and pathways of this disease to reveal the molecular mechanisms...
Aquaporin-8 is a novel marker for progression of human cervical cancer cells [0.03%]
人宫颈癌细胞增殖的新标志物AQP-8
Weibo Li,Yizuo Song,Chunyu Pan et al.
Weibo Li et al.
Background: Role of aquaporin-8 (AQP8) in cervical cancer has not been fully elucidated. Objective: We aim to explore the impacts of AQ...
Identification of immune cell infiltration pattern and related critical genes in metastatic castration-resistant prostate cancer by bioinformatics analysis [0.03%]
基于生物信息学分析鉴定转移性去势抵抗性前列腺癌的免疫细胞浸润模式及关键基因
Caibin Fan,Wei Lu,Kai Li et al.
Caibin Fan et al.
Background: Metastatic castration-resistant prostate cancer (mCRPC) is the lethal stage of prostate cancer and the main cause of morbidity and mortality, which is also a potential target for immunotherapy. ...
Influence of Arg399Gln, Arg280His and Arg194Trp XRCC1 gene polymorphisms of Base Excision Repair pathway on the level of 8-oxo-guanine and risk of head and neck cancer in the Polish population [0.03%]
多项修正的碱基切除修复通路中的XRCC1基因多态性对波兰人群头颈部肿瘤DNA损伤及发病风险的影响研究
Jacek Kabzinski,Monika Maczynska,Dariusz Kaczmarczyk et al.
Jacek Kabzinski et al.
Background: Reduced efficiency of DNA repair systems has long been a suspected factor in increasing the risk of cancer. Objective: In t...
Alterations of epigenetic regulators and P53 mutations in murine mesenchymal stem cell cultures: A possible mechanism of spontaneous transformation [0.03%]
小鼠间充质干细胞培养中表观遗传调控因子的改变和P53突变：自发转化的一种可能机制
Ayman Mohamed Metwally,Hanchen Li,JeanMarie Houghton
Ayman Mohamed Metwally
Background: Recent studies demonstrated the involvement of mesenchymal stem/stromal cells (MSCs) in carcinogenesis, but the molecular mechanism behind this transformation is still obscured. ...
O-GlcNAcylation in early stages of chronic lymphocytic leukemia: Protocol development for flow cytometry [0.03%]
慢性淋巴细胞性白血病早期阶段的O-GlcNAc酰化：流式细胞术协议开发
Viktória Temesfői,Kinga Molnár,Péter Kaltenecker et al.
Viktória Temesfői et al.
Background: Recent studies proved that metabolic changes in malignant disorders have an impact on protein glycosylation, however, only a few attempts have been made so far to use O-GlcNAc analysis as a prognostic tool. Gl...
AS1 expression in prostate cancer and its effects on proliferation and invasion of prostate cancer cells [0.03%]
雄激素受体反式激活域相互作用蛋白1在前列腺癌中的表达及其对前列腺癌细胞增殖和侵袭的影响研究
Yuxin Li,Xiaohong Zhuang,Li Zhuang et al.
Yuxin Li et al.
This paper aimed at investigating AS1 expression in prostate cancer (PCa) and its effects on the proliferation and invasion of prostate cancer cells (PCCs). The prostate tissues and the matched adjacent normal prostate tissues excised and p...