Keqiang Li,Aravind Raveendran,Guoqing Xie et al.
Keqiang Li et al.
Non-muscle invasive bladder cancer (NMIBC) has a high recurrence rate, which places a significant burden on both patients and the healthcare system. Hence, it holds significant importance to predict the recurrence risk following treatment f...
lncRNA ARAP1-AS1 enhances proliferation and impairs apoptosis of lymphoma cells by sponging miR-6867-5p [0.03%]
长链非编码RNA ARAP1-AS1通过海绵作用吸附miR-6867-5p促进淋巴瘤细胞增殖并抑制其凋亡
Bo Pang,Yanfang Gan,Jing Wang et al.
Bo Pang et al.
Background: Numerous evidence have suggested the vital role of lncRNAs in human tumorigenesis. And lncRNA APAP1-AS1 has been proved to act as an oncogene. ...
Identification of novel potential genes in testicular germ cell tumors: A transcriptome analysis [0.03%]
睾丸生殖细胞肿瘤新型潜在基因的鉴定：转录组分析
Shaokai Zheng,Ting Li,Lianglin Qiu
Shaokai Zheng
Objective: Testicular germ cell tumors (TGCTs), containing pure seminoma and non-seminoma, occupy the most majority of testicular cancers in adolescents and young men, which has increased dramatically in recent decades. T...
Chaofeng Wang,Dezhi Song,Qian Huang et al.
Chaofeng Wang et al.
Cancer has become a leading cause of morbidity and mortality in recent years. Its high prevalence has had a severe impact on society. Researchers have achieved fruitful results in the causative factors, pathogenesis, treatment strategies, a...
Pyrimidinergic receptor P2Y6 expression is elevated in lung adenocarcinoma and is associated with poor prognosis [0.03%]
嘧啶受体P2Y6在肺腺癌中表达升高并与预后不良相关
Xiuli Wang,Baoshan Zhao,Dan Ren et al.
Xiuli Wang et al.
Backgroud: Previous in vitro studies have indicated that pyrimidinergic receptor P2Y6 (P2RY6, P2Y6 receptor) may function as a cancer-promoting factor in lung adenocarcinoma (LUAD). However, the prognostic significance of...
Machine learning methods revealed the roles of immune-metabolism related genes in immune infiltration, stemness, and prognosis of neuroblastoma [0.03%]
机器学习方法揭示了免疫代谢相关基因在神经母细胞瘤免疫浸润、干细胞特性及预后中的作用
Jianhua Mu,Jianan Gong,Peng Lin et al.
Jianhua Mu et al.
Background: Immunometabolism plays an important role in neuroblastoma (NB). However, the mechanism of immune-metabolism related genes (IMRGs) in NB remains unclear. This study aimed to explore the effects of IMRGs on the ...
Immunological function and prognostic value of lymphoid-specific helicase in liver hepatocellular carcinoma [0.03%]
淋巴特异性解旋酶在肝细胞肝癌中的免疫功能及预后价值
Yuan Fang,Weiqiang Tang,Dan Zhao et al.
Yuan Fang et al.
Background: Lymphoid-specific helicase (HELLS), a SNF2-like chromatin-remodeling enzyme, plays a key role in tumor progression via its DNA methylation function. However, the effects of HELLS on immune infiltration and pro...
Association of single nucleotide polymorphism miRNA-146a (rs2910164) with increased predisposition to oral squamous cell carcinoma in central India population [0.03%]
miRNA-146a（rs2910164）单核苷酸多态性与中央印度人群口腔鳞状细胞癌易感性的关联研究
Shikha Tiwari,Ritu Pandey,Vinay Kumar et al.
Shikha Tiwari et al.
Background: miRNAs play a crucial role in the genesis of cancer, either as tumor suppressor genes or as oncogenes. Single Nucleotide Polymorphisms (SNPs) in the seed region of microRNAs (miRNAs) can dysregulate their leve...
TRB CDR3-cancer testis antigen chemical complementarity scoring for identifying productive immune responses in renal cell carcinoma [0.03%]
基于TRB CDR3-癌睾抗原化学互补性评分的肾细胞癌免疫识别反应的鉴定
Tabitha R Hudock,Vayda R Barker,Brandon J Manley et al.
Tabitha R Hudock et al.
Background: Immunogenomics approaches to the characterization of renal cell carcinoma (RCC) have helped to better our understanding of the features of RCC immune dysfunction. However, much is still unknown with regard to ...
Granzymes expression patterns predict immunotherapy response and identify the heterogeneity of CD8+ T cell subsets [0.03%]
粒酶表达模式预测免疫治疗的疗效并揭示CD8+t细胞亚群的异质性
Jing Li,Huibo Zhang,Jie Wu et al.
Jing Li et al.
Background: Recent studies illustrated the effects of granzymes (GZMs) gene alterations on immunotherapy response of cancer patients. Thus, we aimed to systematically analyze the expression and prognostic value of GZMs fo...