Integrative analysis of histone acetyltransferase KAT2A in human cancer [0.03%]
人类癌症中组蛋白乙酰转移酶KAT2A的集成分析
Hua Li,Chun Li,Lu-Zong Yang et al.
Hua Li et al.
The high incidence of mutations and the crucial roles of KAT2A in cancer development have received increased attention. Nevertheless, a systematic comparison of the heterogeneity and dynamics across different cancer types has not been condu...
STEAP3 is a prognostic biomarker that promotes glioma progression by regulating immune microenvironment and PI3K-AKT pathway [0.03%]
STEAP3通过调节免疫微环境和PI3K-AKT途径促进胶质瘤进展的预后生物标志物
Zihan Song,Zijun Zhao,Siyu Zhu et al.
Zihan Song et al.
Background: STEAP3 is a metal reductase located on the plasma membrane close to the nucleus and vesicles. Despite numerous studies indicating the involvement of STEAP3 in tumor advancement, the prognostic value of STEAP3 ...
Subgroup identification of targeted therapy effects on biomarker for time to event data [0.03%]
基于生物标志物的靶向治疗亚组识别在生存数据分析中的应用
Gajendra K Vishwakarma,Atanu Bhattacharjee,Fatih Tank et al.
Gajendra K Vishwakarma et al.
Background: The initiation biomarker-driven trials have revolutionized oncology drug development by challenging the traditional phased approach and introducing basket studies. Notable successes in non-small cell lung canc...
The clinical value of a nomogram constructed from CEA, CA199, PT, FIB, tumor differentiation and TNM stage in colorectal cancer [0.03%]
基于CEA、CA199、PT、FIB、肿瘤分化及TNM分期的结直肠癌临床预后列线图模型的研究价值分析
Kang Wang,Lulu Ma,Liying Chen et al.
Kang Wang et al.
Background: The accurate Tumor-Node-Metastasis (TNM) staging of colorectal cancer (CRC) is of great guiding significance for the judgment of tumor progression and prognosis, and the formulation of treatment strategies. ...
Comprehensive analysis of thirteen-gene panel with prognosis value in Multiple Myeloma [0.03%]
含预后价值的多发性骨髓瘤十三基因Panel检测全面分析
Tingting Zheng,Panpan Chen,Yuanlin Xu et al.
Tingting Zheng et al.
Background: Although there are many treatments for Multiple myeloma (MM), patients with MM still unable to escape the recurrence and aggravation of the disease. ...
Albumin-bilirubin score predicts trastuzumab resistance in HER2-positive breast cancer [0.03%]
白蛋白-胆红素评分可预测HER2阳性乳腺癌曲妥珠单抗耐药性
Wen-Juan Huang,Jia-Rui Yuan,Lei Zhang et al.
Wen-Juan Huang et al.
The albumin-bilirubin (ALBI) score is a novel indicator of liver function. Some studies showed that the ALBI score was a predictive marker for the prognosis and efficacy of drug therapy in malignancies. We aimed to assess the predicted role...
Urinary VOCs as biomarkers of early stage lung tumour development in mice [0.03%]
小鼠肺肿瘤早期发展的尿液挥发性标记物的鉴定
Flora Gouzerh,Gwenaëlle Vigo,Laurent Dormont et al.
Flora Gouzerh et al.
Background: Lung cancer is the primary cause of cancer-induced death. In addition to prevention and improved treatment, it has increasingly been established that early detection is critical to successful remission. ...
HPV genotype-specific distribution and attributable risk in cervical intraepithelial neoplasia in a referral population with a history of LSIL [0.03%]
人乳头状瘤病毒基因型分布及在宫颈上皮内瘤变中的归因风险：一项针对低级别鳞状上皮内病变病史人群的研究
Sam Ratnam,Dan Jang,Reza Alaghehbandan et al.
Sam Ratnam et al.
Background and objective: CINtec PLUS and cobas HPV tests (Roche) were previously ascertained for triaging an LSIL referral population [1]. As part of this study, genotype-specific distribution and attributable risk of hi...
Long-chain noncoding RNA LINC01569 upregulates filamin A-interacting protein 1-like to prevent metastasis of triple-negative breast cancer via sponging miR-300 [0.03%]
长链非编码RNA LINC01569通过海绵吸附miR-300上调肌动蛋白交联蛋白1类似物以防止三阴性乳腺癌的转移
Xinyu Jiang,Juli Lin,Zhanlin Zhu
Xinyu Jiang
Background: Long-chain noncoding RNA (lncRNA), LINC01569, is important for regulating the extracellular matrix, which affects cell migration. However, its involvement in the occurrence and development of triple-negative b...
DNALI1 is a prognosis-related biomarker and correlates with immune infiltrates in low grade glioma [0.03%]
DNALI1是一种预后相关的生物标志物并与低级别胶质瘤中的免疫浸润相关
Yapeng Lu,Panpan Chang,Jiangpei Bian et al.
Yapeng Lu et al.
Background: Dynein axonemal light intermediate chain 1 (DNALI1) is a component of axonemal dyneins and its role in cancer progression is not known. Object...