The Mediator complex subunit MED15, a promoter of tumour progression and metastatic spread in renal cell carcinoma [0.03%]
肾细胞癌中促进肿瘤进展和转移的中介复合物亚基MED15
Richard Weiten,Tim Müller,Doris Schmidt et al.
Richard Weiten et al.
Background/objective: MED15 is a part of the multiprotein Mediator complex which is involved in the transcription of polymerase (Pol) II-dependent genes. Several studies in this field have reported altered expressions of ...
Plasma exosomes as novel biomarker for the early diagnosis of gastric cancer [0.03%]
血浆外泌体作为胃癌早期诊断新生物标志物的研究
Jianjun Wang,Yuanyuan Liu,Wangwei Sun et al.
Jianjun Wang et al.
Exosomes are lipid bilayer vesicles of endocytic origin ranging from 30 to 100 nm in size, and contain various nucleic acid molecules such as DNA, mRNA, miRNA, lncRNA and multiple proteins, which could be transferred into target cells. Rece...
Synergistic role of Caspase-8 and Caspase-3 expressions: Prognostic and predictive biomarkers in colorectal cancer [0.03%]
Caspase-8和Caspase-3表达的协同作用：结直肠癌中的预后及预测生物标志物
Qiang Yao,Weimin Wang,Jun Jin et al.
Qiang Yao et al.
Background: Expressions of Caspase-8 and Caspase-3 have been identified as important markers in many malignant tumors, but their roles in colorectal cancer (CRC) have not been confirmed. The purpose of this study was to i...
miR-34 increases in vitro PANC-1 cell sensitivity to gemcitabine via targeting Slug/PUMA [0.03%]
微RNA-34通过靶向Slug/PUMA增加PANC-1细胞系对吉西他滨的敏感性
Qing-An Zhang,Xu-Hai Yang,Dong Chen et al.
Qing-An Zhang et al.
miR-34 was deregulated in tumor tissues compared with corresponding noncancerous tissue samples. Furthermore, miR-34 may contribute to cancer-stromal interaction associated with cancer progression. However, whether miR-34 could decrease che...
Expression of CD105 cancer stem cell marker in three subtypes of renal cell carcinoma [0.03%]
三种类型的肾细胞癌中癌症干细胞标志物CD105的表达
Leili Saeednejad Zanjani,Zahra Madjd,Maryam Abolhasani et al.
Leili Saeednejad Zanjani et al.
Background: CD105 is recently described as a cancer stem cell (CSC) marker. Objective: The present study was aimed to investigate the e...
Shuang Fu,Li Liu,Xin Zhang et al.
Shuang Fu et al.
Background: Laryngeal cancer is one of the most common malignancies in the head and neck. Activated platelets play a critical role in cancer development and progression. Altered mean platelet volume (MPV) and platelet dis...
lncRNA-HEIH in serum and exosomes as a potential biomarker in the HCV-related hepatocellular carcinoma [0.03%]
血液和外泌体中的长链非编码RNA-HIGH作为HCV相关肝细胞癌潜在生物标志物的作用研究
Chun Zhang,Xi Yang,Quan Qi et al.
Chun Zhang et al.
Background: Chronic hepatitis C (CHC) is a contagious liver disease that results from infection with the hepatitis C virus (HCV). The most serious consequence of CHC is HCV-related hepatocellular carcinoma (HCC). ...
Tumor-infiltrating lymphocytes are associated with β-catenin overexpression in breast cancer [0.03%]
肿瘤浸润淋巴细胞与乳腺癌中β-连环蛋白过度表达相关
Xingcong Ma,Xiaoyao Zhao,Wanjun Yan et al.
Xingcong Ma et al.
Background: Inhibition of lymphocytes infiltration and activity may impair antitumor immune response and limit treatment responsiveness. Wnt/β-catenin pathway has been suggested to contribute to immune evasion in tumor b...
Resveratrol enhances the effects of ALA-PDT on skin squamous cells A431 through p38/ MAPK signaling pathway [0.03%]
白藜芦醇通过p38/MAPK信号途径增强阿魏酸光动力疗法对皮肤鳞状细胞的影响
Xin Zhang,Xia Liu,Shuxia Kang et al.
Xin Zhang et al.
Aims and background: Squamous cell carcinoma (SCC) is one of the most common skin cancers. Photodynamic therapy (PDT) is a non-invasive treatment for SCC, but it is usually effective only on tumors just under the skin. Re...
Knockdown of lncRNA GHET1 suppresses cell proliferation, invasion and LATS1/YAP pathway in non small cell lung cancer [0.03%]
长链非编码RNA GHET1敲低通过抑制LATS1/YAP信号通路来抑制非小细胞肺癌的增殖和侵袭能力
Zhen-Biao Guan,Yu-Shu Cao,Yi Li et al.
Zhen-Biao Guan et al.
Background: The aim in this study was to explore the role of long non-coding RNA GHET1 in development of non small cell lung cancer (NSCLC). Methods: ...