Inhibition of E-cadherin expression by lnc-RNA H19 to facilitate bladder cancer metastasis [0.03%]
lnc-RNA H19通过抑制E-钙黏着蛋白的表达促进膀胱癌转移
Zunwei Zhu,Lieyu Xu,Yong Wan et al.
Zunwei Zhu et al.
Bladder cancer is derived from bladder mucosa and is the most common malignant tumor in urinary system. Long non-coding RNA (lnc-RNA) has high tissue specificity and can participate in cell proliferation and differentiation at various level...
Baicalein suppresses non small cell lung cancer cell proliferation, invasion and Notch signaling pathway [0.03%]
黄芩素通过抑制 notch 信号通路来抑制非小细胞肺癌的增殖和侵袭
Guangfeng Su,Hao Chen,Xinhua Sun
Guangfeng Su
Background: Baicalein is an important Chinese herbal medicine and has multiple pharmacological activities. However, the biological mechanisms of the anti-tumor effects of Baicalein on non small cell lung cancer (NSCLC) st...
Lower serum CA125 level, negative vascular invasion, and wild BRAF were strongly associated with better 2-year disease-free survival in patients with stage III colorectal cancer who received adjuvant chemotherapy [0.03%]
血清CA125水平较低、无血管侵袭和BRAF野生型与III期结直肠癌患者接受辅助化疗后2年无病生存率较好显著相关
Shu-Jian Chang,Xiao-Song Ge,Zhen-Yu Xu et al.
Shu-Jian Chang et al.
Background: Adjuvant chemotherapy plays important role in the comprehensive treatment of patients with stage III colorectal cancer. However, there is few molecular markers for predicting the therapeutic effect. ...
Is serum survivin expression a predictive biomarker in locally advanced gastric cancer patients treated with neoadjuvant chemotherapy? [0.03%]
血清Survivin表达能否作为局部进展期胃癌术前化疗的预测性生物标志物？
Yakup Bozkaya,Nuriye Yıldırım Özdemir,Sevilay Sezer et al.
Yakup Bozkaya et al.
Background: The potential prognostic value of survivin is variably reported depending on the gastric cancer. Objective: Evaluation of t...
Down-regulated serum miR-126 is associated with aggressive progression and poor prognosis of gastric cancer [0.03%]
胃癌进展及预后相关的血清miR-126下调表达研究
Runhua Feng,Maneesh K Beeharry,Sheng Lu et al.
Runhua Feng et al.
Background: miR-126 functions as a tumor suppressor in gastric cancer (GC), however, the clinical significance of serum miR-126 in GC remains unclear. Obj...
Potential biomarkers for the early diagnosis of colorectal adenocarcinoma - transcriptomic analysis of four clinical stages [0.03%]
用于结直肠腺癌早期诊断的潜在生物标志物-四个临床分期的转录组分析
Grażyna Janikowska,Tomasz Janikowski,Alina Pyka-Pająk et al.
Grażyna Janikowska et al.
Backgrounds: Colorectal cancer is the third most common cancer in economically developed countries. Molecular studies and, in particular, gene expression have contributed to advances in the diagnosis and treatment of many...
MicroRNA-136 functions as a tumor suppressor in osteosarcoma via regulating metadherin [0.03%]
微小核糖核酸-136通过调控间皮细胞黏附分子在骨肉瘤中发挥抑癌作用
Tao Guo,Guobiao Pan
Tao Guo
Background: Accumulating studies have reported the abnormal expression of microRNA-136 (miR-136) in numerous types of human cancer, and its involvement in cancer initiation and progression. However, there are no investiga...
Evaluation of neutrophil-to-lymphocyte ratio in newly diagnosed patients receiving borte- zomib-based therapy for multiple myeloma [0.03%]
评估中西医结合治疗新生代患者的粒细胞与淋巴细胞比率
Xin Zhou,Jing Wang,Jun Xia et al.
Xin Zhou et al.
Background: The neutrophil-to-lymphocyte ratio (NLR) at diagnosis has been identified as an independent prognostic marker in several malignancies. Recently, a few studies have reported that an elevated pretreatment NLR is...
Predictive gene signatures of nodal metastasis in papillary thyroid carcinoma [0.03%]
乳头状甲状腺癌淋巴结转移的预测性基因标志物
Kyu Young Choi,Jin Hwan Kim,Il Seok Park et al.
Kyu Young Choi et al.
Background: Cervical lymph node metastases (LNM) in papillary thyroid carcinomas (PTCs) are common and develop in approximately 30-80% of PTCs. The presence of cervical LNM significantly increases the rate of locoregional...
The study of sclareol in inhibiting proliferation of osteosarcoma cells by apoptotic induction and loss of mitochondrial membrane potential [0.03%]
石竹内酯通过诱导凋亡和线粒体膜电位丧失抑制骨肉瘤细胞增殖的作用机制研究
Guoqing Duan,Su Hou,Jianjun Ji et al.
Guoqing Duan et al.
Sclareol (sclarcol) is an organic compound extracted from sage clary plants. Recent study has showed its anti-tumor effects against breast cancer, gastric carcinoma, osteosarcoma and colorectal cancer. However, its exact mechanisms in inhib...