Prognostic and predictive value of long non-coding RNA GAS5 and mircoRNA-221 in colorectal cancer and their effects on colorectal cancer cell proliferation, migration and invasion [0.03%]
长链非编码RNA GAS5和微小核糖核酸-221在结直肠癌预后及预测价值及其对结直肠癌细胞增殖、迁移和侵袭的影响
Lin Liu,Tao Meng,Xin-Hui Yang et al.
Lin Liu et al.
Background: LncRNA and microRNA play an important role in the development of human cancers; they can act as a tumor suppressor gene or an oncogene. LncRNA GAS5, originating from the separation from tumor suppressor gene c...
Phytochemical and anti-inflammatory activities of aqueous leaf extract of Indian borage (oregano) on rats induced with inflammation [0.03%]
印度薄荷(牛至)叶提取物的植物化学和抗炎活性研究
David Bolaji Akinbo,Augustine A Onyeaghala,Jennifer Ochuko Emomidue et al.
David Bolaji Akinbo et al.
Background: The Indian borage (Plectranthus amboinicus) also called Oregano contains many effective antioxidants, which includes caffeic acid, rosmarinic acid and flavonoids. It has been employed in traditional medicine f...
Prognostic value of baseline carcinoembryonic antigen and cytokeratin 19 fragment levels in advanced non-small cell lung cancer [0.03%]
基线癌胚抗原和细胞角蛋白19片段水平对晚期非小细胞肺癌的预后价值
Ae Rin Baek,Hyun Jung Seo,June Hyuk Lee et al.
Ae Rin Baek et al.
Background: Serum carcinoembryonic antigen (CEA) and cytokeratin 19 fragment (CYFRA 21-1) levels are prognostic predictors in non-small cell lung cancer (NSCLC). However, even in patients with the same stage of cancer, th...
Circulating HOTAIR expression predicts the clinical response to neoadjuvant chemotherapy in patients with breast cancer [0.03%]
循环表达的HOTAIR预测乳腺癌患者新辅助化疗的临床疗效
Rongzhao Lu,Jie Zhang,Wei Zhang et al.
Rongzhao Lu et al.
Background: Long noncoding RNA HOTAIR has been detected in the serum of patients with various malignances and may be served as novel biomarker for diagnosis and prognosis prediction of breast cancer. However, the value of...
LncRNA SNHG12 promotes the proliferation and metastasis of papillary thyroid carcinoma cells through regulating wnt/β-catenin signaling pathway [0.03%]
长链非编码RNA SNHG12通过调控Wnt/β-catenin信号通路促进乳头状甲状腺癌细胞的增殖和转移
Shimei Ding,Wei Qu,Yang Jiao et al.
Shimei Ding et al.
Objective: To investigate the expression and role of long non-coding RNA (lncRNA) small nucleolar RNA host gene 12 (SNHG12) in papillary thyroid carcinoma (PTC). ...
Inhibition of E-cadherin expression by lnc-RNA H19 to facilitate bladder cancer metastasis [0.03%]
lnc-RNA H19通过抑制E-钙黏着蛋白的表达促进膀胱癌转移
Zunwei Zhu,Lieyu Xu,Yong Wan et al.
Zunwei Zhu et al.
Bladder cancer is derived from bladder mucosa and is the most common malignant tumor in urinary system. Long non-coding RNA (lnc-RNA) has high tissue specificity and can participate in cell proliferation and differentiation at various level...
Baicalein suppresses non small cell lung cancer cell proliferation, invasion and Notch signaling pathway [0.03%]
黄芩素通过抑制 notch 信号通路来抑制非小细胞肺癌的增殖和侵袭
Guangfeng Su,Hao Chen,Xinhua Sun
Guangfeng Su
Background: Baicalein is an important Chinese herbal medicine and has multiple pharmacological activities. However, the biological mechanisms of the anti-tumor effects of Baicalein on non small cell lung cancer (NSCLC) st...
Lower serum CA125 level, negative vascular invasion, and wild BRAF were strongly associated with better 2-year disease-free survival in patients with stage III colorectal cancer who received adjuvant chemotherapy [0.03%]
血清CA125水平较低、无血管侵袭和BRAF野生型与III期结直肠癌患者接受辅助化疗后2年无病生存率较好显著相关
Shu-Jian Chang,Xiao-Song Ge,Zhen-Yu Xu et al.
Shu-Jian Chang et al.
Background: Adjuvant chemotherapy plays important role in the comprehensive treatment of patients with stage III colorectal cancer. However, there is few molecular markers for predicting the therapeutic effect. ...
Is serum survivin expression a predictive biomarker in locally advanced gastric cancer patients treated with neoadjuvant chemotherapy? [0.03%]
血清Survivin表达能否作为局部进展期胃癌术前化疗的预测性生物标志物?
Yakup Bozkaya,Nuriye Yıldırım Özdemir,Sevilay Sezer et al.
Yakup Bozkaya et al.
Background: The potential prognostic value of survivin is variably reported depending on the gastric cancer. Objective: Evaluation of t...
Down-regulated serum miR-126 is associated with aggressive progression and poor prognosis of gastric cancer [0.03%]
胃癌进展及预后相关的血清miR-126下调表达研究
Runhua Feng,Maneesh K Beeharry,Sheng Lu et al.
Runhua Feng et al.
Background: miR-126 functions as a tumor suppressor in gastric cancer (GC), however, the clinical significance of serum miR-126 in GC remains unclear. Obj...